ID G7YTS0_CLOSI Unreviewed; 1386 AA.
AC G7YTS0;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Tensin {ECO:0000313|EMBL:GAA56350.1};
GN ORFNames=CLF_110694 {ECO:0000313|EMBL:GAA56350.1};
OS Clonorchis sinensis (Chinese liver fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Clonorchis.
OX NCBI_TaxID=79923 {ECO:0000313|EMBL:GAA56350.1, ECO:0000313|Proteomes:UP000008909};
RN [1] {ECO:0000313|EMBL:GAA56350.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Henan {ECO:0000313|EMBL:GAA56350.1};
RX PubMed=22023798; DOI=10.1186/gb-2011-12-10-r107;
RA Wang X., Chen W., Huang Y., Sun J., Men J., Liu H., Luo F., Guo L., Lv X.,
RA Deng C., Zhou C., Fan Y., Li X., Huang L., Hu Y., Liang C., Hu X., Xu J.,
RA Yu X.;
RT "The draft genome of the carcinogenic human liver fluke Clonorchis
RT sinensis.";
RL Genome Biol. 12:R107-R107(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Henan;
RA Wang X., Huang Y., Chen W., Liu H., Guo L., Chen Y., Luo F., Zhou W.,
RA Sun J., Mao Q., Liang P., Zhou C., Tian Y., Men J., Lv X., Huang L.,
RA Zhou J., Hu Y., Li R., Zhang F., Lei H., Li X., Hu X., Liang C., Xu J.,
RA Wu Z., Yu X.;
RT "The genome and transcriptome sequence of Clonorchis sinensis provide
RT insights into the carcinogenic liver fluke.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; DF144229; GAA56350.1; -; Genomic_DNA.
DR Proteomes; UP000008909; Unassembled WGS sequence.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR45734:SF10; BLISTERY, ISOFORM A; 1.
DR PANTHER; PTHR45734; TENSIN; 1.
DR Pfam; PF00017; SH2; 1.
DR PRINTS; PR00401; SH2DOMAIN.
DR SMART; SM00252; SH2; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR PROSITE; PS50001; SH2; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008909};
KW SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191}.
FT DOMAIN 1133..1253
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT REGION 64..119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 309..422
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 806..834
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 64..82
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 102..119
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 354..372
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 374..392
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 394..422
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1386 AA; 152682 MW; BC9EB4269AC75BAC CRC64;
MPTQIDPNQP LFGQNKGLEN NRLIVSVSTN LAGIIIQCTA LTEMERKTSI STFNGRRHVN
LSDNEKYDSS ERETDDSVKI PIRHLSSKSS KVMKKTTESS ETPIRSRSGS SERTTSSIRK
QNCHDSHCSY CFPQGASRHF HGHQFFHRAD TPEDSEAVTS LSKNPSSPQA MAAVADHFTS
ISSRSTPHSE LFTQMEPLFP QYAELHEGPK PLKAVVDEVK SSGPGKNNGH SLEVHFAKPE
TIIKCETRPP GWGRRIVTAP TIEVTFAQPV HTSSNVTPGG TSGANGEEHM NGLQAAGIEN
VQLMKAEGQP NLPYVSPPEK RDVVRSEPSA ESRLSPSGIR HTGRPPTVGS GRPDDALHST
TTSASNQPGR SGYSAHRERL RQERERELLM RQQQKRQLAA SSTGLNEQLH QQNRQQQQYR
SLSAVNTPSV SEAVEEIETV VLQFIGRGVQ DVDSRVGSMT TLPRGRGGSM TDGISVYVDD
RFVIGLGRRT QSAFVQILFH RSRLICIPDE LAEKVELLQH VLRSDNSPDC LIVKRLRISD
EEAQVAVPKG SVYPDTFYTA QCALMYCHVA SQLIRFQISY NRDVHCWCAL MRRNLNSSLG
VEQLQQFSHT VTSAYFTYVY TCQSTATTDM SHACMPLSVN TNQMFLSETG LPGENNYISM
RSYFSVPLHQ SNMVGTEKPA PNGTLRTSDA DVSVSRLPVA KPLGQSPTSD SRVGQCRYSQ
NGVTPALCSL ARLTNPLEVD VSLTDTKPVA RSQMQKFIPR VMSRGDDTKV GREIAGVSPV
TVHSEQAAPL QEIEKHEDMK ALQLAPRSSL ESTENEDLGL QNVDSSQRGG LAKRGYSSTQ
GVQETSLITN WKILLVVACC DMDRSFKVSS LDGPVERTRT HELLRHAVRS RVTHVCKVPR
KLYQHWEHRS QPKFSSQTTE TAEVYHVFEE IYFILDAWMS VRGSIQHILS HDDSLLQTSK
YLQRAYVIDK LVNLNISLMD WSVSSKTSSI KQTSKRPLFK LCISGVLNEW HPYNVCQIVT
ENSRFLARNN SNSDLVKPMP MHQSQTMISP SPQPLQASRF NTSATLVNHS QATVLLNGSR
GHLSPTNSTA APTTTTPVIT NGWKVDGSFK QPFIDRGQDN GNLGIVQDTA PSWYRPKLSR
EAAINILRQQ PPGNFLIRDS TTFKGAYGLA VKVATLPPKV TQKSGFTKFV RSLLNDLQSE
LVRHYLIEVV NTPTRGVRLK GFASEPVFPS LAALIHQHTI DPLALPCRLI LPPVPTNLPS
SGSATLPPLV IGTVKHASAV EDGAMPDNVT VASSGSVRGA PSSEVGSLHT DGPVGPPHRM
DGIAQMPIQV HDNPVPSHNV PYVCVVREGS SPQRRSPLDI TGNQGLTSPF GVDTDRLGLF
IKIQYA
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