ID   G8BD20_CANPC            Unreviewed;       776 AA.
AC   G8BD20;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=Methyltransferase domain-containing protein {ECO:0000259|Pfam:PF13847};
GN   OrderedLocusNames=CPAR2_208080 {ECO:0000313|CGD:CAL0000152089,
GN   ECO:0000313|EMBL:CCE43165.1};
OS   Candida parapsilosis (strain CDC 317 / ATCC MYA-4646) (Yeast) (Monilia
OS   parapsilosis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=578454 {ECO:0000313|EMBL:CCE43165.1, ECO:0000313|Proteomes:UP000005221};
RN   [1] {ECO:0000313|Proteomes:UP000005221}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 317 / ATCC MYA-4646 {ECO:0000313|Proteomes:UP000005221};
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA   Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA   Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA   Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA   Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA   Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA   Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
RN   [2] {ECO:0000313|Proteomes:UP000005221}
RP   GENOME REANNOTATION.
RC   STRAIN=CDC 317 / ATCC MYA-4646 {ECO:0000313|Proteomes:UP000005221};
RX   PubMed=22192698; DOI=10.1186/1471-2164-12-628;
RA   Guida A., Lindstaedt C., Maguire S.L., Ding C., Higgins D.G., Corton N.J.,
RA   Berriman M., Butler G.;
RT   "Using RNA-seq to determine the transcriptional landscape and the hypoxic
RT   response of the pathogenic yeast Candida parapsilosis.";
RL   BMC Genomics 12:628-628(2011).
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DR   EMBL; HE605206; CCE43165.1; -; Genomic_DNA.
DR   AlphaFoldDB; G8BD20; -.
DR   STRING; 578454.G8BD20; -.
DR   EnsemblFungi; CPAR2_208080-T; CPAR2_208080-T-p1; CPAR2_208080.
DR   CGD; CAL0000152089; CPAR2_208080.
DR   VEuPathDB; FungiDB:CPAR2_208080; -.
DR   eggNOG; ENOG502QQCH; Eukaryota.
DR   Proteomes; UP000005221; Chromosome 2.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR021829; DUF3419.
DR   InterPro; IPR025714; Methyltranfer_dom.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR47473; BTA1P; 1.
DR   PANTHER; PTHR47473:SF1; METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF11899; DUF3419; 1.
DR   Pfam; PF13847; Methyltransf_31; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000005221}.
FT   DOMAIN          105..217
FT                   /note="Methyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF13847"
SQ   SEQUENCE   776 AA;  88234 MW;  7914B23611C98855 CRC64;
     MIDFDFITSD LSKMKVFTSV SLFCGIVYFV AKLNKTINSI LVFCWACFVK PLIQKKTGKT
     GVKNQQQNLE LFYKNQAHIY DTTRTVLLKG RKECLRLAIS HLQKKKDLVW IDIGGGTGSN
     IEFMNQVSNI SKNFKAVYLV DLSPSLCEVA RNRFAAHEWT NVHVLVADAC DFTIDYKSAD
     LITFSYSLSM IPTFNAAIDN AVSKLDKQGI IATVDFGIQS NDTSIGRVNT LGGLVNRNIP
     WILRNFWRIW FEADKVFLDS SRRNYLEYKF GTIKSVNQYN KTLGRIPYYI WIGCDKARSS
     QILTRLNCLA TESPYLAPSS SPRQVSESMP VSKGHEAAIA NLQKNLPFPS LYYQKEVWRV
     YYDEMNHLYE QFKNQYIYAF TWEDPREDHK ILNFTSDDTV LAITSAGDNI LSYATLPTAP
     KRIHAVDLNP CQNHLLELKL ASFRALTQDQ IWQMFGEGHI DNFTDLLIDK LAPHMSSNAF
     QYWMAKGPKA FTGKGLYDTG SSRWAIRFGR IIFKVCGISQ HVTALCKASR IEEQKQIWNE
     HIKPVLFNRI VGSFLVGNPI FLWKALGVPA NQAKMMGPSV IKYVVDTLDP IIERSLISED
     NYFYYLCLMG RYSRTNCPDY LTTKGYKRLT GQKSITGEVP IDNIRLHTDL LNDVFARLSN
     KSITIAIIMD HIDWFDPNGV DVINEITAIK QCLVKGGRVM LRSAATHPWY IKTFESLGFK
     CEAAAIRESG SSIDRVNMYA STWVCTNLDG KEDVVTVPSD ITKLDAGRRR MSSLKI
//