ID G8EB08_9HYPO Unreviewed; 1858 AA.
AC G8EB08;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=LteA {ECO:0000313|EMBL:AEQ61507.1};
GN Name=lteA {ECO:0000313|EMBL:AEQ61507.1};
OS Epichloe brachyelytri.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Epichloe.
OX NCBI_TaxID=79589 {ECO:0000313|EMBL:AEQ61507.1};
RN [1] {ECO:0000313|EMBL:AEQ61507.1}
RP NUCLEOTIDE SEQUENCE.
RA Pan J., Schardl C.;
RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; JF800660; AEQ61507.1; -; Genomic_DNA.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd00155; RasGEF; 1.
DR CDD; cd06224; REM; 1.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR Gene3D; 1.20.870.10; Son of sevenless (SoS) protein Chain: S domain 1; 1.
DR InterPro; IPR008937; Ras-like_GEF.
DR InterPro; IPR000651; Ras-like_Gua-exchang_fac_N.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23113:SF364; GUANINE NUCLEOTIDE EXCHANGE FACTOR LTE1; 1.
DR Pfam; PF00617; RasGEF; 1.
DR Pfam; PF00618; RasGEF_N; 1.
DR SMART; SM00147; RasGEF; 1.
DR SMART; SM00229; RasGEFN; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
DR PROSITE; PS50212; RASGEF_NTER; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW ECO:0000256|PROSITE-ProRule:PRU00168}.
FT DOMAIN 409..536
FT /note="N-terminal Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50212"
FT DOMAIN 1611..1854
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50009"
FT REGION 1..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 178..249
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 627..647
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 705..745
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 887..910
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 989..1013
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1049..1097
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1293..1317
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1456..1522
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1543..1595
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 13..31
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 34..48
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 53..70
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 195..223
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 224..247
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 629..647
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 718..733
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1456..1472
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1473..1490
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1858 AA; 203055 MW; 4FE067A3F6EE16C1 CRC64;
MASADPLDVT RPSFPSLSAS ATPTGHRPRT QTSPKRVAAK DEKPRKVSPL LSRPFATKTS
ASAAKPTTTK WIPRTFARGT STASKPLVPL SERRSRERNR GMTGRIETDM DNAEVVPNGR
SAGREGRQFT VANVGNNGRI YLRPSVRPAH QRYPQPNFTF PITPPSTAIV DSWSQSNGAN
LADANTKERG EDEGSLQTTP WTPTTSATPL AGDRQLTSGA ETSSRPIRHR RAMSDSTVHE
ASANRDQDSH GFKVAISTAQ GRDEQRPRTM DDLNAIANGP MLNVNIPSWR LGTPRFTLRG
TPMLRGSSYA PTEDARSSTI SAGLNSSSLP PNSTVHGFSA RKRPKALAVP TSHTHFVAQR
GAPGVPSPRL LRPLRSTYMS THMVIEPAMF TDLTFKPSCD DGLIVRYSAA GAVTAATPPR
LVAEITSPSF LDYELISDFF LTFRSFLEPS DLLRMLVARL RWALDRDDEV GMIVRVRTFV
ALRHWILNYF VDDFLLEHSL RVTFCNLLND FVDELSQDFY SRRVQIRILA ELKKCWRRVC
AQYWDGDEFD DSLGPDIAVT PGGIAGSRDP HLDPTTAPET LPIEPDQHDA VAMPSPSPSL
LQAQHATLRN EIPNPIPVGD FVVLDNRPGT PECQTSGPRN PEQRPTSPYS LASMDIVSCS
FPGKNMKSFN QSTAHLLAAH PVPSTAVGNA TTGPIATTPK ALVGKRVRPT QAHKRNNSLS
DSLREHHSDR ASSTDQECLP APSSGGSLVR GNLLPPGQAF VDVQPLGRHG HANRQTTVFQ
PKSRDFTKDG MSGGATSGHG MRKLLRSVRK ALKNRGQGLY PTQQAFTDIQ FAGPRGATVN
RLPGTAVVPQ GTTIRQNGSR PPVRIDLLGA EVAEDFKKAI REEEEEAVTA AAGGGTHGQQ
FGGVSIQPPP KSAPLLSTFP ENSASRMDST TLEALTQHHR QRPFSDMAIT VGSKSIVIVD
DTVPFELPSV HGTHGVEIPS VDAFCDSLVR GGADPTPPNT PPSHSFDGGI PRRSSHLLNP
HVVGANMVED VLPPFIPDLA TLEGSHSLRT SEYHTQPSMS AIRPGGEGRL SSRGASRPHR
RARSWRSQQS LNSVLHRRDT SLGSVGIPPA LRSLDATTDS GGLYRDHFTQ VSIPEPLRVL
RRRPGGDLKA VINVGDLDRF ILRRSQSVGS LATYTESIRS SYMLSSRPNS AGEFVAGIES
SDQGRADVFS LGQLAERPKK RDLSLFSTHS SKPIMRPSFE AEAQKLAQIP DDDDDGIESA
LLKLEGKFLP KKPINLSIIG HNPRPVEDTA VEAEKNAEHP TITEQPTGAD PDKTPKLGNV
DGLSMRPALD EASPTFWGAT DGQARDAHLS PTELRSFLSE GSHDSYCSIP LLQRGLGDET
TEPVTHAWTE RSILRGSDDE ESLNEPGLEQ FQNISPGDQY SSFELVQKTA SMEMVEVGET
VFSMASVMED ASFLKDDSAD SSDLSSDLSD DDVHVDVVDD DDDDDDDDTV SQREGEIRVG
HVSHCGSPPH PLSDEPTVMR SRPSSPQITL VQALAMSPDG LVAPGKSDAR PKKPLPPTPV
LTPVVGCSET PRSTAEISRH GEPLSNAAQP NTNTATTPKH LVHLPFILAF DSDVLAQQFT
LIEKDALTEI DWRELTDMSW KHFACSNSRS WVDFLRNIDA QGVDVVIARF NIMVKWAISE
IVLTQQVEER ARCIIKLIHI AAHCRRYRNF ATLAQLTIAL SSNEVSRLSK TWELVPERDL
QTLHDLEILV TPSRNFHNIR EEMEVGTDRG CIPFVGIYTH DLLYNAQRPS EIAGSPTNAP
LVNFEKCRCG AAVVKTLLRL LEASTRYTFQ PIEGVTERCL WIGALSDNEI RRYSQNLE
//
