ID G8FU62_TASV2 Unreviewed; 167 AA.
AC G8FU62;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 08-NOV-2023, entry version 36.
DE RecName: Full=Non-structural polyprotein 1AB {ECO:0000256|ARBA:ARBA00019743};
DE Flags: Fragment;
OS Turkey astrovirus 2 (TAstV-2).
OC Viruses; Riboviria; Orthornavirae; Pisuviricota; Stelpaviricetes;
OC Stellavirales; Astroviridae; Avastrovirus; Avastrovirus 3.
OX NCBI_TaxID=246343 {ECO:0000313|EMBL:AER45381.1};
OH NCBI_TaxID=9103; Meleagris gallopavo (Wild turkey).
RN [1] {ECO:0000313|EMBL:AER45381.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=291758_08 {ECO:0000313|EMBL:AER45381.1};
RX PubMed=22545544; DOI=10.1637/9831-061311-Reg.1;
RA Canelli E., Cordioli P., Barbieri I., Catella A., Pennelli D., Ceruti R.,
RA Moreno A., Lavazza A.;
RT "Astroviruses as causative agents of poultry enteritis: genetic
RT characterization and longitudinal studies on field conditions.";
RL Avian Dis. 56:173-182(2012).
CC -!- FUNCTION: Contains the viral protease participating in the cleavage of
CC the polyprotein into functional products. It contains also the
CC activities necessary for replication of genomic RNA, as well as
CC transcription of subgenomic mRNA. {ECO:0000256|ARBA:ARBA00029407}.
CC -!- SUBCELLULAR LOCATION: Host membrane {ECO:0000256|ARBA:ARBA00004301};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004301}.
CC -!- SIMILARITY: Belongs to the astroviridae polyprotein 1AB family.
CC {ECO:0000256|ARBA:ARBA00005873}.
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DR EMBL; JN048381; AER45381.1; -; Genomic_RNA.
DR GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR GO; GO:0039694; P:viral RNA genome replication; IEA:InterPro.
DR CDD; cd23172; ps-ssRNAv_Astroviridae_RdRp; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001205; RNA-dir_pol_C.
DR InterPro; IPR007094; RNA-dir_pol_PSvirus.
DR Pfam; PF00680; RdRP_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50507; RDRP_SSRNA_POS; 1.
PE 3: Inferred from homology;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Ribosomal frameshifting {ECO:0000256|ARBA:ARBA00022758};
KW RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Viral RNA replication {ECO:0000256|ARBA:ARBA00022953}.
FT DOMAIN 51..167
FT /note="RdRp catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50507"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AER45381.1"
FT NON_TER 167
FT /evidence="ECO:0000313|EMBL:AER45381.1"
SQ SEQUENCE 167 AA; 20031 MW; 6D6FA92475D0B303 CRC64;
PIFTRIGAMF EQDQNNRMKQ QTETRSAQVG WTPFFGGLDR RVRRLCGDGD RYFVEMDWTR
YDGTIPKPLF WRIRQIRFFF LHDSHKTQKM RRLYNWYVKN LLEKIILLPT GEVCQVKKGN
PSGQYSTTVD NNMINVWLTT FEISFLFFKQ RGRLPTEKEL QENCSMI
//
