ID   G8J8U4_9HIV1            Unreviewed;       300 AA.
AC   G8J8U4;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   24-JAN-2024, entry version 43.
DE   SubName: Full=Envelope glycoprotein {ECO:0000313|EMBL:AET74103.1};
DE   Flags: Fragment;
GN   Name=env {ECO:0000313|EMBL:AET74103.1};
OS   Human immunodeficiency virus 1.
OC   Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC   Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus.
OX   NCBI_TaxID=11676 {ECO:0000313|EMBL:AET74103.1};
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1] {ECO:0000313|EMBL:AET74103.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=E6591 {ECO:0000313|EMBL:AET74103.1};
RX   PubMed=22072758; DOI=10.1128/JVI.06126-11;
RA   de Silva T.I., Aasa-Chapman M., Cotten M., Hue S., Robinson J.,
RA   Bibollet-Ruche F., Sarge-Njie R., Berry N., Jaye A., Aaby P., Whittle H.,
RA   Rowland-Jones S., Weiss R.;
RT   "Potent Autologous and Heterologous Neutralizing Antibody Responses Occur
RT   in HIV-2 Infection across a Broad Range of Infection Outcomes.";
RL   J. Virol. 86:930-946(2012).
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DR   EMBL; JN863747; AET74103.1; -; Genomic_RNA.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0019031; C:viral envelope; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.5.170; -; 1.
DR   Gene3D; 2.170.40.20; Human immunodeficiency virus 1, Gp160, envelope glycoprotein; 1.
DR   InterPro; IPR036377; Gp120_core_sf.
DR   InterPro; IPR000777; HIV1_Gp120.
DR   Pfam; PF00516; GP120; 1.
DR   SUPFAM; SSF56502; gp120 core; 1.
DR   SUPFAM; SSF58069; Virus ectodomain; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Viral envelope protein {ECO:0000313|EMBL:AET74103.1};
KW   Virion {ECO:0000313|EMBL:AET74103.1}.
FT   TRANSMEM        240..263
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          2..239
FT                   /note="Human immunodeficiency virus 1 envelope glycoprotein
FT                   Gp120"
FT                   /evidence="ECO:0000259|Pfam:PF00516"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AET74103.1"
FT   NON_TER         300
FT                   /evidence="ECO:0000313|EMBL:AET74103.1"
SQ   SEQUENCE   300 AA;  33350 MW;  1EA2EFD52A67C7D7 CRC64;
     IRSENISNNA KTIIVQLNEP VKINCTRPSN NTRKSWNIGP GQAFYATGDI IGDIRQAHCN
     VSRKEWNNTL YKVAAQLRKQ LNITGLTFAN HSGGDLEITT HSFNCRGEFF YCNTTKLFNS
     TWDDSTGDNN STDNNSTGDT ITLQCRIRQI VRMWQRVGQA MYAPPIQGEI RCESNITGLL
     LTRDGSANET FRNETFRPGG GDMKDNWRSE LYKYKVVKIE PLGVAPTHAK RRVVEREKRA
     VGLGAVFIGF LGAAGSTMGA ASITLTVQAR QLLSGIVQQQ SNLLKAIEAQ QHLLKLTVWG
//