ID G8JQL7_ERECY Unreviewed; 683 AA.
AC G8JQL7;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=polynucleotide adenylyltransferase {ECO:0000256|ARBA:ARBA00012388};
DE EC=2.7.7.19 {ECO:0000256|ARBA:ARBA00012388};
GN OrderedLocusNames=Ecym_3523 {ECO:0000313|EMBL:AET39001.1};
OS Eremothecium cymbalariae (strain CBS 270.75 / DBVPG 7215 / KCTC 17166 /
OS NRRL Y-17582) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX NCBI_TaxID=931890 {ECO:0000313|EMBL:AET39001.1, ECO:0000313|Proteomes:UP000006790};
RN [1] {ECO:0000313|Proteomes:UP000006790}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 270.75 / DBVPG 7215 / KCTC 17166 / NRRL Y-17582
RC {ECO:0000313|Proteomes:UP000006790};
RX DOI=10.1534/g3.111.000745;
RA Leh Louis V., Despons L., Friedrich A., Martin T., Durrens P.,
RA Casaregola S., Neuveglise C., Fairhead C., Marck C., Cruz J.A.,
RA Straub M.L., Kugler V., Sacerdot C., Uzunov Z., Thierry A., Weiss S.,
RA Bleykasten C., De Montigny J., Jacques N., Jung P., Lemaire M., Mallet S.,
RA Morel G., Richard G.F., Sarkar A., Savel G., Schacherer J., Seret M.L.,
RA Talla E., Samson G., Jubin C., Poulain J., Vacherie B., Barbe V.,
RA Pelletier E., Sherman D.J., Westhof E., Weissenbach J., Baret P.V.,
RA Wincker P., Gaillardin C., Dujon B., Souciet J.L.;
RT "Pichia sorbitophila, an interspecies yeast hybrid reveals early steps of
RT genome resolution following polyploidization.";
RL G3 (Bethesda) 2:299-311(2012).
CC -!- SIMILARITY: Belongs to the DNA polymerase type-B-like family.
CC {ECO:0000256|ARBA:ARBA00008593}.
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DR EMBL; CP002499; AET39001.1; -; Genomic_DNA.
DR RefSeq; XP_003645818.1; XM_003645770.1.
DR AlphaFoldDB; G8JQL7; -.
DR STRING; 931890.G8JQL7; -.
DR GeneID; 11469097; -.
DR KEGG; erc:Ecym_3523; -.
DR eggNOG; KOG1906; Eukaryota.
DR HOGENOM; CLU_013572_5_0_1; -.
DR InParanoid; G8JQL7; -.
DR OMA; FGSCATD; -.
DR OrthoDB; 21395at2759; -.
DR Proteomes; UP000006790; Chromosome 3.
DR GO; GO:1990817; F:poly(A) RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0016070; P:RNA metabolic process; IEA:UniProt.
DR CDD; cd05402; NT_PAP_TUTase; 1.
DR Gene3D; 1.10.1410.10; -; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR002058; PAP_assoc.
DR InterPro; IPR002934; Polymerase_NTP_transf_dom.
DR InterPro; IPR045862; Trf4-like.
DR PANTHER; PTHR23092:SF15; INACTIVE NON-CANONICAL POLY(A) RNA POLYMERASE PROTEIN TRF4-2-RELATED; 1.
DR PANTHER; PTHR23092; POLY(A) RNA POLYMERASE; 1.
DR Pfam; PF01909; NTP_transf_2; 1.
DR Pfam; PF03828; PAP_assoc; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF81631; PAP/OAS1 substrate-binding domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006790}.
FT DOMAIN 213..309
FT /note="Polymerase nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF01909"
FT DOMAIN 380..440
FT /note="PAP-associated"
FT /evidence="ECO:0000259|Pfam:PF03828"
FT REGION 1..162
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 538..683
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 34..58
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 65..98
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 125..139
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 140..162
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 543..568
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 610..625
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 628..645
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 660..675
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 683 AA; 76680 MW; 810976670C4DDC80 CRC64;
MKQGASSNSK RFGSKANPSS KRGKVKKMRK SSLSRVQRNF SVFHNSSEHE NKYANLSVVN
SDGEEVILIE DDEVNDDESG VMQEIDLGED EDSNEEYDED GSSKSSYENA GKSSGNALDK
NDDFIGFSSS DEEHGANGEH QSSDTSSSYE EETTEQEVSA PKVMQLNNDY PWILNHDHSK
QKEIADWLTL EIKDFVSYIS PNREEIRKRN DAITKIRKAV KSFWPDSDLH CFGSYATDLY
LPGSDIDCVV NSKSGDKDNK NALYSFASYL RKNGLASQVS VIAKARVPII KFVEPVSQIH
IDVSFERTNG VDAAKIIRGW LGDTPGLREL VLTIKQFLYA RRLNDVHIGG LGGFSIICLT
YSFLKLHPRI ICQDVDPLQN LGVLLIDFFE LYGKNFGYDD VGIAVSADDA KYINKKDYPE
LTQNLRGSFN LVIQDPGDPC NNISRGTFNV RDIKKAFAGA FDLLANKCFE LDAATFKVRL
GKSILGNVIK YRGARRDFKD ERGLVVNKAI QENEEFHQKR GRIVLSRDDD EFINISDEED
MYDIEEPPKK KSKKNTSNVA KSKDRKARQP PVLPPYTVHT GQNIKYESSD DYDPTGNDLV
VIESRGADVN AHSSAKQNAS SRSEGQIDKL MGLDDTEDKD DYQPVLANNH SDGAQEDDDQ
EDYVPKVDKE TKRNYWLGKG QSM
//
