ID   G8JQR8_ERECY            Unreviewed;      1032 AA.
AC   G8JQR8;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   24-JAN-2024, entry version 52.
DE   RecName: Full=Mitochondrial presequence protease {ECO:0008006|Google:ProtNLM};
GN   OrderedLocusNames=Ecym_3585 {ECO:0000313|EMBL:AET39052.1};
OS   Eremothecium cymbalariae (strain CBS 270.75 / DBVPG 7215 / KCTC 17166 /
OS   NRRL Y-17582) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=931890 {ECO:0000313|EMBL:AET39052.1, ECO:0000313|Proteomes:UP000006790};
RN   [1] {ECO:0000313|Proteomes:UP000006790}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 270.75 / DBVPG 7215 / KCTC 17166 / NRRL Y-17582
RC   {ECO:0000313|Proteomes:UP000006790};
RX   DOI=10.1534/g3.111.000745;
RA   Leh Louis V., Despons L., Friedrich A., Martin T., Durrens P.,
RA   Casaregola S., Neuveglise C., Fairhead C., Marck C., Cruz J.A.,
RA   Straub M.L., Kugler V., Sacerdot C., Uzunov Z., Thierry A., Weiss S.,
RA   Bleykasten C., De Montigny J., Jacques N., Jung P., Lemaire M., Mallet S.,
RA   Morel G., Richard G.F., Sarkar A., Savel G., Schacherer J., Seret M.L.,
RA   Talla E., Samson G., Jubin C., Poulain J., Vacherie B., Barbe V.,
RA   Pelletier E., Sherman D.J., Westhof E., Weissenbach J., Baret P.V.,
RA   Wincker P., Gaillardin C., Dujon B., Souciet J.L.;
RT   "Pichia sorbitophila, an interspecies yeast hybrid reveals early steps of
RT   genome resolution following polyploidization.";
RL   G3 (Bethesda) 2:299-311(2012).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP002499; AET39052.1; -; Genomic_DNA.
DR   RefSeq; XP_003645869.1; XM_003645821.1.
DR   AlphaFoldDB; G8JQR8; -.
DR   STRING; 931890.G8JQR8; -.
DR   MEROPS; M16.A04; -.
DR   GeneID; 11469169; -.
DR   KEGG; erc:Ecym_3585; -.
DR   eggNOG; KOG0961; Eukaryota.
DR   HOGENOM; CLU_006065_0_0_1; -.
DR   InParanoid; G8JQR8; -.
DR   OMA; CVEGPFW; -.
DR   OrthoDB; 227593at2759; -.
DR   Proteomes; UP000006790; Chromosome 3.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 4.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   PANTHER; PTHR43016:SF16; METALLOPROTEASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G07610)-RELATED; 1.
DR   PANTHER; PTHR43016; PRESEQUENCE PROTEASE; 1.
DR   Pfam; PF00675; Peptidase_M16; 1.
DR   Pfam; PF05193; Peptidase_M16_C; 1.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 4.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000006790}.
FT   DOMAIN          54..136
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          193..368
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
SQ   SEQUENCE   1032 AA;  118317 MW;  DED3FDFA24E94558 CRC64;
     MVFKKLVSFQ LDYAPEYRLT KFVSSRTRLQ VVHIHSKSSP LVEGYFALGT DCVNDSGAPH
     TLEHLIFMGS KKYPWKGLLD ISGGITMSNT NAWTATDQTV YSLTSAGWVG FKKLLLVYLD
     HIVNPRLTDE ACTTEVYYID PKDLVDKGVV YSEMEGIESA AYSITNLEVQ RLMFPEGNAY
     RSETGGLTKN LRKLSNEEIR KFHAEKYSPD NLCLIICGNV PEDELLDVIQ EFDAELPEFN
     KPKRKRPFLD SPSSQIPRKL SQTIESTVEF PELDESQGEV VISWIGFPYT DHLNDLAASL
     LFDYLTDSSL SPFNKYLVEI ENPLASRVRY HTSDYMRTII NLNVEGVPTE KLNDAKNKIL
     EILETHKIDL TRIRQVIENE KWDYVYGREV GGFQLLAESC ITDFLYGDEE GKILKESLSN
     LNDFETLLTW SVQQWQSFMT RLLNENKPVI VLGKPSSEMY YRLEKEQADL INERKATFSP
     EKIRELQKQL DDAQVANNRP IPRELLDRFA IEKPQESVDF LETRSISTIE HEDNDLKDEL
     TNRILNTRPK DFPLFMHFES FTSQFIELNF LVNSRVVKDT SLLPYYYIFC ELFNMPMKAE
     DDKIISFEDV VKNLKDETIS YNISLELLGQ FTDLIYFGIR CKSVNYGDAV KWIKHCLFDM
     VFDETRVRVL LEKFLNSIFE SKRDGYSMQA SLINRHLFTE RSMKKSTDVL YVEGILRKVL
     DDIDSGEFDS VVLPRLETFR DQLRSYFHKF HILILGDIGK LDDVYKPWEQ LVNKLPMDKS
     QVVIPPTPRS LETVSELGSC PMEVAYVITT PGSASSYMTC VTSIPINLDY QHPDFAAVAL
     ASEYLGCVEG PFWKGIRGSG FAYGAYISKQ YEHNCIGFSI YRGTDIIKCY QTAKHIVEGF
     ADGTTRFDPQ LINAAISSLV LMLASEGNSY FNAAVVKYID NFCKRRGPNF NTKFLTKLAT
     VTVDDLRRVM EKYFVNMFNS EGGAVFMSCH PSKLEPIQEY LESQGYQVNV EELADDPDDE
     FSDCEIVEDL DT
//