ID G8LS53_9FLAO Unreviewed; 416 AA.
AC G8LS53;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 22-FEB-2023, entry version 57.
DE RecName: Full=3-phosphoshikimate 1-carboxyvinyltransferase {ECO:0000256|ARBA:ARBA00012450};
DE EC=2.5.1.19 {ECO:0000256|ARBA:ARBA00012450};
DE AltName: Full=5-enolpyruvylshikimate-3-phosphate synthase {ECO:0000256|ARBA:ARBA00030046};
GN Name=aroA {ECO:0000313|EMBL:AEU09426.1};
GN ORFNames=BLBCPU_383 {ECO:0000313|EMBL:AEU09426.1};
OS Blattabacterium sp. (Cryptocercus punctulatus) str. Cpu.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Blattabacteriaceae; Blattabacterium.
OX NCBI_TaxID=1075399 {ECO:0000313|EMBL:AEU09426.1, ECO:0000313|Proteomes:UP000007112};
RN [1] {ECO:0000313|EMBL:AEU09426.1, ECO:0000313|Proteomes:UP000007112}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Cpu {ECO:0000313|EMBL:AEU09426.1,
RC ECO:0000313|Proteomes:UP000007112};
RX PubMed=22094859;
RA Neef A., Latorre A., Pereto J., Silva F.J., Pignatelli M., Moya A.;
RT "Genome economization in the endosymbiont of the wood roach Cryptocercus
RT punctulatus due to drastic loss of amino acid synthesis capabilities.";
RL Genome Biol. Evol. 3:1437-1448(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-
CC carboxyvinyl)-3-phosphoshikimate + phosphate; Xref=Rhea:RHEA:21256,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:57701, ChEBI:CHEBI:58702,
CC ChEBI:CHEBI:145989; EC=2.5.1.19;
CC Evidence={ECO:0000256|ARBA:ARBA00001901};
CC -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate biosynthesis;
CC chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step
CC 6/7. {ECO:0000256|ARBA:ARBA00004811}.
CC -!- SIMILARITY: Belongs to the EPSP synthase family.
CC {ECO:0000256|ARBA:ARBA00009948}.
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DR EMBL; CP003015; AEU09426.1; -; Genomic_DNA.
DR RefSeq; WP_014246314.1; NC_016621.1.
DR AlphaFoldDB; G8LS53; -.
DR STRING; 1075399.BLBCPU_383; -.
DR KEGG; bcp:BLBCPU_383; -.
DR eggNOG; COG0128; Bacteria.
DR HOGENOM; CLU_024321_0_0_10; -.
DR UniPathway; UPA00053; UER00089.
DR Proteomes; UP000007112; Chromosome.
DR GO; GO:0003866; F:3-phosphoshikimate 1-carboxyvinyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0008652; P:amino acid biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.65.10.10; Enolpyruvate transferase domain; 3.
DR InterPro; IPR001986; Enolpyruvate_Tfrase_dom.
DR InterPro; IPR036968; Enolpyruvate_Tfrase_sf.
DR InterPro; IPR006264; EPSP_synthase.
DR InterPro; IPR023193; EPSP_synthase_CS.
DR InterPro; IPR013792; RNA3'P_cycl/enolpyr_Trfase_a/b.
DR PANTHER; PTHR21090; AROM/DEHYDROQUINATE SYNTHASE; 1.
DR PANTHER; PTHR21090:SF5; PENTAFUNCTIONAL AROM POLYPEPTIDE; 1.
DR Pfam; PF00275; EPSP_synthase; 1.
DR PIRSF; PIRSF000505; EPSPS; 2.
DR SUPFAM; SSF55205; EPT/RTPC-like; 1.
DR PROSITE; PS00885; EPSP_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Aromatic amino acid biosynthesis {ECO:0000256|ARBA:ARBA00023141};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:AEU09426.1}.
FT DOMAIN 61..404
FT /note="Enolpyruvate transferase"
FT /evidence="ECO:0000259|Pfam:PF00275"
SQ SEQUENCE 416 AA; 47840 MW; E8066AA7348787E7 CRC64;
MPSYIKINKK WKSLYGSISI TGSKSISNRL LILKAIYKDD IYIENISNCE DTKVLEKSLY
STSNILNIHH AGTAMRFLTS YLSIQEGKKF ILTGSNRMKE RPISILVDAL KKLGSEIIYL
EKIGYPPIKI IGKKIIGGKI DINARISSQY ISSLMLIASK FKIGLKIYLK EDITSIPYIK
MTFDLLTRAG IKISWKEKII HIYPGKKTGK KYFSIESDWS SASYYYSMAS IVKTSNLTLS
YYQNKSLQGD REITSIYEKY FGVYTIFEKN KIILNKKLNF TLPRFINLDL NKTPDLAQTI
VVTCSSLGIK CYLKGLETLK IKETDRLKAL KNELLKLGVK IKITSSCLEI IDFFPKKMDS
SIRIKTYQDH RMAMAFSSFG LFYSLQIEEP KVVEKSYPNF WMDLQYLGFL INYYEG
//
