ID G8S8I8_ACTS5 Unreviewed; 344 AA.
AC G8S8I8;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Transcriptional regulator, LuxR family {ECO:0000313|EMBL:AEV85085.1};
DE EC=3.4.11.5 {ECO:0000313|EMBL:AEV85085.1};
GN OrderedLocusNames=ACPL_4190 {ECO:0000313|EMBL:AEV85085.1};
OS Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110).
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=134676 {ECO:0000313|EMBL:AEV85085.1, ECO:0000313|Proteomes:UP000005440};
RN [1] {ECO:0000313|Proteomes:UP000005440}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 31044 / CBS 674.73 / SE50/110
RC {ECO:0000313|Proteomes:UP000005440};
RA Schwientek P., Szczepanowski R., Kalinowski J., Klein A., Selber K.,
RA Wehmeier U.F., Stoye J., Puehler A.;
RT "The complete genome sequence of the acarbose producer Actinoplanes sp.
RT SE50/110.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP003170; AEV85085.1; -; Genomic_DNA.
DR RefSeq; WP_014691157.1; NZ_LT827010.1.
DR AlphaFoldDB; G8S8I8; -.
DR STRING; 134676.ACPL_4190; -.
DR KEGG; ase:ACPL_4190; -.
DR PATRIC; fig|134676.3.peg.4106; -.
DR eggNOG; COG2197; Bacteria.
DR eggNOG; COG2267; Bacteria.
DR HOGENOM; CLU_020336_14_0_11; -.
DR OrthoDB; 27092at2; -.
DR Proteomes; UP000005440; Chromosome.
DR GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd06170; LuxR_C_like; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000073; AB_hydrolase_1.
DR InterPro; IPR013595; Pept_S33_TAP-like_C.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR43433:SF8; BLL8011 PROTEIN; 1.
DR PANTHER; PTHR43433; HYDROLASE, ALPHA/BETA FOLD FAMILY PROTEIN; 1.
DR Pfam; PF00561; Abhydrolase_1; 1.
DR Pfam; PF08386; Abhydrolase_4; 1.
DR Pfam; PF00196; GerE; 1.
DR PRINTS; PR00111; ABHYDROLASE.
DR PRINTS; PR00038; HTHLUXR.
DR SMART; SM00421; HTH_LUXR; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR PROSITE; PS50043; HTH_LUXR_2; 1.
PE 4: Predicted;
KW Aminopeptidase {ECO:0000313|EMBL:AEV85085.1};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Hydrolase {ECO:0000313|EMBL:AEV85085.1};
KW Protease {ECO:0000313|EMBL:AEV85085.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000005440}.
FT DOMAIN 276..341
FT /note="HTH luxR-type"
FT /evidence="ECO:0000259|PROSITE:PS50043"
SQ SEQUENCE 344 AA; 36912 MW; 7D2718BA859F0668 CRC64;
MSGPGQRIAS TTSPGGARIG YATVGSGPPL VFVTGWLSHL ELSWALPAER GFFQALADGR
RLIRYDKPGC GLSTAAGDGP HTMEREVDAL RAVVDATGLE RFDLVGISTG AAVAAAWAAR
EPRSVSRLVL YGGWPYGPDV ASPEIRTHVL GLIREHWGLA SDLLGGVFAP DADPGTRAAF
VRYQREAATA EVAGAMLLMA YRIDVLDLLP SISAPTLVVH RERDRAAPIE QGRRLADGIP
GARLEVVPGR SHLPYIGDYR PITRAIRQFL GLPAAHRGAA PGLTERQREV AALIAQGRTN
REIGERLGIT ERSAEAHVER IRTRMDFRSR AQIAAWYVAT AGPA
//
