ID G8SG95_ACTS5 Unreviewed; 420 AA.
AC G8SG95;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Esterase {ECO:0000313|EMBL:AEV84211.1};
DE EC=3.1.1.- {ECO:0000313|EMBL:AEV84211.1};
GN Name=estA {ECO:0000313|EMBL:AEV84211.1};
GN OrderedLocusNames=ACPL_3316 {ECO:0000313|EMBL:AEV84211.1};
OS Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110).
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=134676 {ECO:0000313|EMBL:AEV84211.1, ECO:0000313|Proteomes:UP000005440};
RN [1] {ECO:0000313|Proteomes:UP000005440}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 31044 / CBS 674.73 / SE50/110
RC {ECO:0000313|Proteomes:UP000005440};
RA Schwientek P., Szczepanowski R., Kalinowski J., Klein A., Selber K.,
RA Wehmeier U.F., Stoye J., Puehler A.;
RT "The complete genome sequence of the acarbose producer Actinoplanes sp.
RT SE50/110.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP003170; AEV84211.1; -; Genomic_DNA.
DR AlphaFoldDB; G8SG95; -.
DR STRING; 134676.ACPL_3316; -.
DR KEGG; ase:ACPL_3316; -.
DR PATRIC; fig|134676.3.peg.3231; -.
DR eggNOG; COG2755; Bacteria.
DR eggNOG; COG4833; Bacteria.
DR HOGENOM; CLU_653202_0_0_11; -.
DR OrthoDB; 227157at2; -.
DR Proteomes; UP000005440; Chromosome.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR CDD; cd00161; RICIN; 1.
DR CDD; cd01823; SEST_like; 1.
DR Gene3D; 2.80.10.50; -; 2.
DR Gene3D; 3.40.50.1110; SGNH hydrolase; 1.
DR InterPro; IPR035992; Ricin_B-like_lectins.
DR InterPro; IPR000772; Ricin_B_lectin.
DR InterPro; IPR037460; SEST-like.
DR InterPro; IPR013830; SGNH_hydro.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR PANTHER; PTHR37981; LIPASE 2; 1.
DR PANTHER; PTHR37981:SF1; SGNH_HYDRO DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13472; Lipase_GDSL_2; 1.
DR Pfam; PF00652; Ricin_B_lectin; 1.
DR SMART; SM00458; RICIN; 1.
DR SUPFAM; SSF50370; Ricin B-like lectins; 1.
DR SUPFAM; SSF52266; SGNH hydrolase; 1.
DR PROSITE; PS50231; RICIN_B_LECTIN; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR637460-2};
KW Hydrolase {ECO:0000313|EMBL:AEV84211.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000005440}.
FT DOMAIN 291..419
FT /note="Ricin B lectin"
FT /evidence="ECO:0000259|SMART:SM00458"
FT ACT_SITE 49
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR637460-1"
FT ACT_SITE 267
FT /evidence="ECO:0000256|PIRSR:PIRSR637460-1"
FT DISULFID 68..92
FT /evidence="ECO:0000256|PIRSR:PIRSR637460-2"
FT DISULFID 142..150
FT /evidence="ECO:0000256|PIRSR:PIRSR637460-2"
FT DISULFID 200..248
FT /evidence="ECO:0000256|PIRSR:PIRSR637460-2"
SQ SEQUENCE 420 AA; 42176 MW; 0C7538D341F83878 CRC64;
MLHGARSPGG RRLLYAVVTL AVAGAVAGVS SVADAAVVTG LHYVAIGSSF AAGPGISPVQ
SSTGAAACAR SSNNYASVVA RDLGADLTDV SCSGATTANV LTTSQNGLPP QIQAVTSATD
VVTITVGGND VDYLGSMGAY TCQNDGGSTC ASVDRAAIDK AFADEPARLQ NVVNAVHSAA
PQAQVYLVNY FTILPDSGTC SGVPLTADQV AYERSIATRL AAATATAASA AGATLVDVAA
ASHGHDACAA DPWVENGHPP TGRTQYHPNA TGMRNAAQVI EAALAARGQV RAAEFRSGIA
GKCVDVAGAG TADGTPVQLY TCNGTVAQRW TFTPGAGGSL RVLGKCLDIS NGGTANSTRV
QLWTCNGTGA QRWTLGAGSS LVNPQSGRCL DDPGGSTSDG NQLQIFDCNA TVAQQWTPTT
//
