ID G8TKK4_NIAKG Unreviewed; 3654 AA.
AC G8TKK4;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Amino acid adenylation domain protein {ECO:0000313|EMBL:AEV98678.1};
DE EC=5.1.1.3 {ECO:0000313|EMBL:AEV98678.1};
GN OrderedLocusNames=Niako_2334 {ECO:0000313|EMBL:AEV98678.1};
OS Niastella koreensis (strain DSM 17620 / KACC 11465 / NBRC 106392 /
OS GR20-10).
OC Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC Niastella.
OX NCBI_TaxID=700598 {ECO:0000313|EMBL:AEV98678.1, ECO:0000313|Proteomes:UP000005438};
RN [1] {ECO:0000313|EMBL:AEV98678.1, ECO:0000313|Proteomes:UP000005438}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17620 / KACC 11465 / NBRC 106392 / GR20-10
RC {ECO:0000313|Proteomes:UP000005438};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Han J., Lapidus A., Bruce D., Goodwin L., Pitluck S., Peters L.,
RA Kyrpides N., Mavromatis K., Ivanova N., Mikhailova N., Davenport K.,
RA Saunders E., Detter J.C., Tapia R., Han C., Land M., Hauser L.,
RA Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Tindall B.,
RA Pomrenke H., Brambilla E., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Niastella koreensis GR20-10.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
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DR EMBL; CP003178; AEV98678.1; -; Genomic_DNA.
DR RefSeq; WP_014218592.1; NC_016609.1.
DR STRING; 700598.Niako_2334; -.
DR KEGG; nko:Niako_2334; -.
DR PATRIC; fig|700598.3.peg.2403; -.
DR eggNOG; COG1020; Bacteria.
DR HOGENOM; CLU_000022_0_0_10; -.
DR OrthoDB; 9778383at2; -.
DR Proteomes; UP000005438; Chromosome.
DR GO; GO:0008881; F:glutamate racemase activity; IEA:UniProtKB-EC.
DR CDD; cd05930; A_NRPS; 2.
DR CDD; cd12117; A_NRPS_Srf_like; 1.
DR CDD; cd19531; LCL_NRPS-like; 3.
DR Gene3D; 3.30.300.30; -; 3.
DR Gene3D; 3.40.50.980; -; 6.
DR Gene3D; 1.10.1200.10; ACP-like; 3.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 4.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 4.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 3.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 3.
DR Pfam; PF13193; AMP-binding_C; 3.
DR Pfam; PF00668; Condensation; 4.
DR Pfam; PF00550; PP-binding; 3.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 3.
DR SUPFAM; SSF47336; ACP-like; 3.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 8.
DR PROSITE; PS00455; AMP_BINDING; 3.
DR PROSITE; PS50075; CARRIER; 3.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 3.
PE 4: Predicted;
KW Isomerase {ECO:0000313|EMBL:AEV98678.1};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT DOMAIN 1037..1112
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 2096..2171
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 3156..3231
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 3654 AA; 409038 MW; BABE4DBEB559F4C9 CRC64;
MKKLLADIRD NNILLEVVNG ELKVFAESNP DPLLLAEIKK RKSDLLQILS GNSSVNPGGV
PDLFIPLVAQ SRDYVLSSAQ RRLWVLNQLE PESSAYNLRG SHVFEGELNV AGLEFAFNSL
IARHEILRTV FKINDHGEVR QYVLTPEASG TAIMYVDLCN YADQETQLNV SIHQAERTSF
NLAEGPLLKA TLYKMSDGKW VFSYVMHHII GDAWSTGVLV RELMTIYNAR IRNEVVPLTP
LRIQYKDFAA WQQQQLAGSM AETNKTYWLK QFEGDIPVFN LATGKTRPAV KSNQGGVVRA
TINSRLTAAI KKLGGEEGAT LFMTMLALVK TLLYRYTGQE DIVIGTSIAS REHIELENQI
GFYVNTLALR TRFNGQQNFK ELLNKVGEVT MGAFAHQDFP FDELVDSLEP DRDRSRHPLF
DVMVVLQNIN LASNKTTEPR QLNKINVKEH RSIEHVVNKF DLTFFITDTG EQLLLRIVYD
KDMYDAGLIQ RMAGHLEQLI DAIITEPAAP LTGLDLLDAA ETKQLLDDFG TSAVSYPAQH
NIITIFEEQV AKTPDAIALV AGKAVLSYAG FNEKVNRLAN FLKKEHGIGA NDRVGIVLDR
SEKLIIAMFG VLKAGGSYVV IEPDNPASRQ AYITRDAGVK LLITQTDHLF NVSYYNGPVF
AIDVQLDTLE TSPHCETRIQ PEHLAYLVYT SGTTGEPKGV MVTHSNVTDY HYGILNATNI
GDCKTFGLVS TAAADLGNTV IYTSLLLGGM LQVYSADEVT NGKKMRQQKP DCIKIVPSHW
KALQDSNDFF LPQKCLVFGG ETLTGDIIEM VRAGQGACDV YNHYGPSETT IGKLIKKVAV
HDKIERVPLG KPFGNTAIYV LDEHASLLPA GVAGEICISG RGLAQGYLNQ PALTAQKFVA
NPFKKGELIY KTGDLGIWLP DGDMLFLGRK DSQVKIRGYR VELGEIEQAL LACEGVTSVI
VLARMIAESE NVLVAYYTGK QAIDPDLLRT HLTNTLPAYM APQHYQQIDH FPLTRNGKID
RKRLPAPEEP AVTNFIGPRN KTEEKLVEIW KEVLDRESVS VTDNFFAVGG HSLRAIRLVN
LIHKTFQVTI GLKDIFATLV LEDQAKMIAN SPRSLWAPIE PAAVSSSGYP LSSAQYRLWL
LSQFEQANIG YVVPSSQVFE GPLDRNALEY AFKNVIERHE ILRTVFREDQ AGEVKQFVLA
PEDASLNITF HDLRNEPQQE QKAQELVNAA YRRPFNLATG PLITACLIGL TDHKWVFSCV
MHHLISDGWS RNILTKELLL FYNSYRNAGS ASLPPLRIQY KDFAVWQRSQ LSGEQMKAHK
AYWLNAFEGE LPVLDILTDR PRPARKTYNG AYSAKIISRQ HADRLKALGK EGDSTLFISL
LAAVNVLLYR HTGQEDIITG TLIAGRQHAD LEDQIGFYVN TLPVRARFTG NDSFIDIQEQ
LRQHSLNAFE YEAYPFDELI QQLELQHDLS RNPLFDVCVS MQTPRKTAAH TGESQKGLSV
SDYSLQNATS SRFDLSFEFV ESGDELRAGL VYNTDLFNKS TAVRLLNHLE QLIIAVIKEP
AKPVRLIEYI SEAEKSQLLY EFNNTGVTYP GDKTVAALFR EQTALTPGKT ALIAGDISID
YKELDKQSDK LAVYLREKYG IKRGDFAGIM ISRSEKLIIA ILGILKAGAA YVPIDPAFPD
ERKDFILKDT GCKVLITQME YAPDLHYFGG RLLEMDIEAL MIAESDTIQY EDPCSTDVAY
VMYTSGSSGT PKGVLVEHRS IVRLLKPDNF AGITQKDVLI STSAIAFDGT TFEYWSMLLN
GGTLVLCEAD ELLDSKRLSA LIKKQGVTVS WFTAGLLNQL VDENIAVFDG LHTIVAGGDK
LSETHVRTLQ QHYPALRIIN GYGPTENTTF STTYTLNPGD NVIPVGRPIN NSFAYILDHY
GQLCPVGVKG EIHVAGDGLA RGYLNNEVLT AEKFIEDPFR KDGRMYRTGD LGCWLPDGNI
LFMGRKDDQV KINGFRVEPG EIENTVQRFP GIQSAVVIAK KIINEEKELT AYFVGEGEID
ITELRTYLAK KLPAFMIPAY FIQLTEMPLT VNGKIDRKNL PEPEGIVLYG AENFVAPRNE
TEEKLAIIWQ EITGRQRIGV KDNFFEVGGH SLRATRLVNL IHKTFEVSIA LKDVFEMPVL
EEQAALIQKA RKNLFIPISP ASMSASGYPL SASQYRLWIL CQLGEVNIAY NVKDVRVFKG
DLNSEALAYA FRSLIQRHEV LRTVFRTDEN GEIKQFILSP DDVGFNMALH DVRGDSTAEN
RIKQLVKDNF TSSFDLAAGP LIRAGLIQRA NQEWVFTCVT HHIISDAWSR SIQMQELMAF
YNSYITGTAP ALKPLRIQYK DFSVWQKEQL GTDLLREHKA YWLKHFEGVL PVLDIPTDKV
RPVVKTYNGS SIKMVFSKEL TDAISSLAKE QEATLFMALL AAVNGLLYIY TSQEDIIIGS
PIAGREHADL EDQVGFYVNT LALRTRFEGT DTFRELLTNV RQVALGAYEH QIYPFDQLVT
DLNLKHDRSR NPLFDVQVIV QNAGNAQKGA GKGKEPFTVG SYGEIGTISC VFDLVFNFEE
SPEGLQVRIA YDPDIYSEWL IKQLGNHLEQ ILDLIITHPD VPINRFDLLN EKDKQQLLSD
FNKTATATDV IKEKTIISLF EEQVLRTPEL TALVFGTTRL TYRQLNEKAG QLARFLKKNY
HVEKNELMGV LLNRSEHMII SILGILKAGA AYVPVNPDYP RSRKDFVLKD TRIKVLITET
TYLFDLDYYQ GNVLAIDIPM PAAEDISPEL QTGSNPEDLV YVIYTSGSSG EPKGVMVENR
GLANTIQASQ RVIAIPPGYK TLQLTSFSFD ASAFEIFLSL ASGAELHIVD DETRNDPAKL
GQFITDHKID WALIPPAYLR VLEIDRIKTL KKLVTAGEAA LANKAREFLR YGEYYNAYGP
TETSICATIM HVRDANLLKN DNIPIGCPIA NSPVYIVNEG NKLAPVGVVG EICVGGAGLA
RGYLHKQSQT VEKFIPNPFV PGERMYKTGD LGRWLPDGVI EYIGRKDEQV KINGNRIEPG
EIESVLMRFP QIEAAVVVPV QDKEGRNELV AYLVSFEPLS TADLVNHITR SLPAFMLPAK
FVQVPHLPIT SNGKIDKKAL PDPYKSALSM GDNYIAPANE TQRKLAMVWE QVLGLEQISV
HDDYFELGGN SLKAMEIIKK IQDTMGCSIP LKVLFEEKTI ESIARQITPG VLTAPSYNQL
AYFSSWNRKG DHLIVLPYES DDIQIDVLTT AINQLVYRHE VLRTEFVRIK EDIKQRILPP
GELSIQVEGP IPVGKEETLD TIILAEHDWE PDLFKAPLFR VRLYRFNNHR FAVLITIHHI
ISDGYSAAVI KNELTALYSA AARNKPMPEA LTFQYRDFSE WQRSFVDSSA GLEHKKYWLQ
KLHDCIISTP FPNFTANNEG NKEDVNKLSL VLDGAFFESI DTFCKKNALT RTSLLLGVLM
LLIHRITNKR DVAICTAVSG RNSRYYGEMD VTGLIGFFAN LLIVRNEIKD AADILQHLKN
VQSGFLDDLQ HDAYPFDKLI DELANGRVED LLKSAVFFNY HNFSDHTNAV YSGEAAESKK
NGDIVTHFGL LFVAKEYKNC LKLNFIFNTT IFPYNQRTAI RNSFTALLQQ ALSA
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