ID G9FJV4_KLEPN Unreviewed; 322 AA.
AC G9FJV4;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=AAA family ATPase {ECO:0000313|EMBL:AEU09832.1};
DE SubName: Full=ATPase AAA family protein {ECO:0000313|EMBL:AHG97140.1};
DE SubName: Full=ATPase associated with various cellular activities (AAA) family protein {ECO:0000313|EMBL:AJM90329.1};
DE SubName: Full=Porphyrin biosynthetic protein {ECO:0000313|EMBL:STS99840.1};
DE EC=6.6.1.2 {ECO:0000313|EMBL:STS99840.1};
GN Name=cobS {ECO:0000313|EMBL:STS99840.1};
GN ORFNames=D647_p47072 {ECO:0000313|EMBL:AHL30390.1}, NCTC13443_00083
GN {ECO:0000313|EMBL:STS99840.1}, p2146_00106
GN {ECO:0000313|EMBL:AJM90329.1}, pCRE114_087
GN {ECO:0000313|EMBL:AGZ05536.1}, pNDM10469_101
GN {ECO:0000313|EMBL:AFC34706.1};
OS Klebsiella pneumoniae.
OG Plasmid IncA/C-LS6 {ECO:0000313|EMBL:AGO62658.1},
OG Plasmid pIMP-PH114 {ECO:0000313|EMBL:AGZ05536.1},
OG Plasmid pKP1-NDM1 {ECO:0000313|EMBL:AHL30390.1},
OG Plasmid pKp55 {ECO:0000313|EMBL:ASF80502.1},
OG Plasmid pNDM-KN {ECO:0000313|EMBL:AEU09832.1},
OG Plasmid pNDM-US-2 {ECO:0000313|EMBL:AJM90329.1},
OG Plasmid pNDM10469 {ECO:0000313|EMBL:AFC34706.1}, and
OG Plasmid pRMH760 {ECO:0000313|EMBL:AHG97140.1}.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX NCBI_TaxID=573 {ECO:0000313|EMBL:AEU09832.1};
RN [1] {ECO:0000313|EMBL:AFC34706.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=N10-0469 {ECO:0000313|EMBL:AFC34706.1};
RC PLASMID=pNDM10469 {ECO:0000313|EMBL:AFC34706.1};
RA Boyd D.A., Mataseje L.F., Mulvey M.R.;
RT "Inc A/C plasmids harbouring the NDM-1 metallo-beta-lactamase.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AEU09832.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Kp7 {ECO:0000313|EMBL:AEU09832.1};
RC PLASMID=pNDM-KN {ECO:0000313|EMBL:AEU09832.1};
RX PubMed=22123704; DOI=10.1128/AAC.05116-11;
RA Carattoli A., Villa L., Poirel L., Bonnin R.A., Nordmann P.;
RT "Evolution of IncA/C blaCMY-2-Carrying Plasmids by Acquisition of the
RT blaNDM-1 Carbapenemase Gene.";
RL Antimicrob. Agents Chemother. 56:783-786(2012).
RN [3] {ECO:0000313|EMBL:AGO62658.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=LS6 {ECO:0000313|EMBL:AGO62658.1};
RC PLASMID=IncA/C-LS6 {ECO:0000313|EMBL:AGO62658.1};
RA c a.;
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:AGO62658.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=LS6 {ECO:0000313|EMBL:AGO62658.1};
RC PLASMID=IncA/C-LS6 {ECO:0000313|EMBL:AGO62658.1};
RX PubMed=23800906; DOI=10.1093/jac/dkt235;
RA Villa L., Capone A., Fortini D., Dolejska M., Rodriguez I., Taglietti F.,
RA De Paolis P., Petrosillo N., Carattoli A.;
RT "Reversion to susceptibility of a carbapenem-resistant clinical isolate of
RT Klebsiella pneumoniae producing KPC-3.";
RL J. Antimicrob. Chemother. 68:2482-2486(2013).
RN [5] {ECO:0000313|EMBL:AGZ05536.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CRE114 {ECO:0000313|EMBL:AGZ05536.1};
RC PLASMID=pIMP-PH114 {ECO:0000313|EMBL:AGZ05536.1};
RX PubMed=24121549; DOI=10.1007/s00284-013-0471-x;
RA Ho P.L., Lo W.U., Chan J., Cheung Y.Y., Chow K.H., Yam W.C., Lin C.H.,
RA Que T.L.;
RT "pIMP-PH114 carrying bla IMP-4 in a Klebsiella pneumoniae strain is closely
RT related to other multidrug-resistant IncA/C2 plasmids.";
RL Curr. Microbiol. 68:227-232(2014).
RN [6] {ECO:0000313|EMBL:AHG97140.1}
RP NUCLEOTIDE SEQUENCE.
RC PLASMID=pRMH760 {ECO:0000313|EMBL:AHG97140.1};
RX PubMed=24841670; DOI=10.1089/mdr.2014.0012;
RA Harmer C.J., Hall R.M.;
RT "pRMH760, a Precursor of A/C2 Plasmids Carrying blaCMY and blaNDM Genes.";
RL Microb. Drug Resist. 20:416-423(2014).
RN [7] {ECO:0000313|EMBL:AJM90329.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC BAA-2146 {ECO:0000313|EMBL:AJM90329.1};
RC PLASMID=pNDM-US-2 {ECO:0000313|EMBL:AJM90329.1};
RA Zhou D., Chen Z., Wang L., Ying Z., Yang H., Liu C., Wang J.;
RT "Production of plasmid-encoding metallo-beta-lactamase NDM-1 in Klebsiella
RT pneumoniae ATCC BAA-2146.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [8] {ECO:0000313|EMBL:AHL30390.1}
RP NUCLEOTIDE SEQUENCE.
RC PLASMID=pKP1-NDM1 {ECO:0000313|EMBL:AHL30390.1};
RA Wailan A.M., Sidjabat H.E., Yam W.K., Alikhan N.N., Petty N.K.,
RA Sartor A.L., Williamson D.A., Forde B.M., Schembri M.A., Beatson S.A.,
RA Paterson D.L., Walsh T.R., Partridge S.R.;
RT "Mechanisms involved in acquisition of blaNDM genes by IncA/C2 and IncFIIY
RT plasmids.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN [9] {ECO:0000313|EMBL:ASF80502.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Kp55 {ECO:0000313|EMBL:ASF80502.1};
RC PLASMID=pKp55 {ECO:0000313|EMBL:ASF80502.1};
RA Papagiannitsis C.C., Dolejska M.;
RT "Characterization of IncA/C2 plasmids, encoding IMP-like metallo-beta-
RT lactamases, recovered from silver gulls in Australia.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
RN [10] {ECO:0000313|EMBL:STS99840.1, ECO:0000313|Proteomes:UP000255518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC13443 {ECO:0000313|EMBL:STS99840.1,
RC ECO:0000313|Proteomes:UP000255518};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the CbbQ/NirQ/NorQ/GpvN family.
CC {ECO:0000256|ARBA:ARBA00009417}.
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DR EMBL; JN157804; AEU09832.1; -; Genomic_DNA.
DR EMBL; JN861072; AFC34706.1; -; Genomic_DNA.
DR EMBL; JX442976; AGO62658.1; -; Genomic_DNA.
DR EMBL; KF250428; AGZ05536.1; -; Genomic_DNA.
DR EMBL; KF976462; AHG97140.1; -; Genomic_DNA.
DR EMBL; KF992018; AHL30390.1; -; Genomic_DNA.
DR EMBL; KJ588779; AJM90329.1; -; Genomic_DNA.
DR EMBL; KY887594; ASF80502.1; -; Genomic_DNA.
DR EMBL; UGKT01000001; STS99840.1; -; Genomic_DNA.
DR RefSeq; WP_000085160.1; NZ_WTDD01000048.1.
DR RefSeq; YP_006958763.1; NC_019153.1.
DR RefSeq; YP_006959115.1; NC_019158.1.
DR RefSeq; YP_008167080.1; NC_021667.1.
DR RefSeq; YP_008725204.1; NC_022652.1.
DR RefSeq; YP_009022225.1; NC_023898.1.
DR RefSeq; YP_009023034.1; NC_023908.1.
DR GeneID; 84238971; -.
DR PATRIC; fig|573.1476.peg.17; -.
DR Proteomes; UP000255518; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0051116; F:cobaltochelatase activity; IEA:UniProtKB-EC.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR011704; ATPase_dyneun-rel_AAA.
DR InterPro; IPR013615; CbbQ_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR42759:SF1; MAGNESIUM-CHELATASE SUBUNIT CHLD; 1.
DR PANTHER; PTHR42759; MOXR FAMILY PROTEIN; 1.
DR Pfam; PF07728; AAA_5; 1.
DR Pfam; PF08406; CbbQ_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:STS99840.1};
KW Plasmid {ECO:0000313|EMBL:AEU09832.1}.
FT DOMAIN 64..188
FT /note="ATPase dynein-related AAA"
FT /evidence="ECO:0000259|Pfam:PF07728"
FT DOMAIN 223..315
FT /note="CbbQ/NirQ/NorQ C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08406"
SQ SEQUENCE 322 AA; 35158 MW; 2D90DD35A46FF9D3 CRC64;
MSQYSQFSVS KVFGMPSIPE KVTAIGYADG SNPFIPATDT NYVFRKEFLR EVLAYLKEPG
GDALFVTGPT GSGKTSGITE IAGRLNWPVQ QITAHGRMEL TDLIGHHALV AEKPGQPPVM
KFMYGPLAVA MREGHLLLIN EVDLADPAEL AGLNDVLEGR PLVIAQNGGE IIKPHPMFRV
VVTGNSTGSG DASGLYQGVM MQNLAAMDRY RFTKVGYADE EAELSILGRA TPKLPENVRK
GMVRIANQVR KLFLGENGED GQISVTMSTR TLVRWAKLSL AFRGAPNALE YALDQALLIR
AAKEEREAIL RVAKDVFGDQ WR
//
