ID G9KRJ0_MUSPF Unreviewed; 252 AA.
AC G9KRJ0;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Signal transducer and activator of transcription 4 {ECO:0000313|EMBL:AES07519.1};
DE Flags: Fragment;
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|EMBL:AES07519.1};
RN [1] {ECO:0000313|EMBL:AES07519.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Lungs {ECO:0000313|EMBL:AES07519.1};
RX PubMed=23236062; DOI=10.1128/JVI.02476-12;
RA Leon A.J., Banner D., Xu L., Ran L., Peng Z., Yi K., Chen C., Xu F.,
RA Huang J., Zhao Z., Lin Z., Huang S.H., Fang Y., Kelvin A.A., Ross T.M.,
RA Farooqui A., Kelvin D.J.;
RT "Sequencing, annotation, and characterization of the influenza ferret
RT infectome.";
RL J. Virol. 87:1957-1966(2013).
CC -!- SIMILARITY: Belongs to the transcription factor STAT family.
CC {ECO:0000256|ARBA:ARBA00005586}.
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DR EMBL; JP018921; AES07519.1; -; mRNA.
DR AlphaFoldDB; G9KRJ0; -.
DR HOGENOM; CLU_014189_3_0_1; -.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0010033; P:response to organic substance; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd10375; SH2_STAT4; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR InterPro; IPR001217; STAT.
DR InterPro; IPR035856; STAT4_SH2.
DR InterPro; IPR048988; STAT_linker.
DR PANTHER; PTHR11801; SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION; 1.
DR PANTHER; PTHR11801:SF19; SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 4; 1.
DR Pfam; PF00017; SH2; 1.
DR Pfam; PF21354; STAT_linker; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR PROSITE; PS50001; SH2; 1.
PE 2: Evidence at transcript level;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW SH2 domain {ECO:0000256|ARBA:ARBA00022999, ECO:0000256|PROSITE-
KW ProRule:PRU00191}.
FT DOMAIN 74..152
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AES07519.1"
FT NON_TER 252
FT /evidence="ECO:0000313|EMBL:AES07519.1"
SQ SEQUENCE 252 AA; 28712 MW; 638B8BADA1F1B40A CRC64;
EVMSWQFSSY VGRGLNSDQL NMLAEKLTVQ PSYNDGNLTW AKFCKEHLPG KSFTFWTWLE
AILDLIKKHI LPLWIDGYVM GFVSKEKERL LLKDKMPGTF LLRFSESHLG GITFTWVDHS
ENGEVRFHSV EPYNKGRLSA LPFADILRDY KVIMAENIPE NPLKYLYPDI PKDKAFGKHY
SSQPCEVSRP TERGDKGYVP SVFIPISTIR SDSTEPHSPS DLLPMSPSVY AVLRENLSPT
TIETAMKSPY SA
//
