ID G9NTB4_HYPAI Unreviewed; 493 AA.
AC G9NTB4;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Homoserine O-acetyltransferase {ECO:0000313|EMBL:EHK45960.1};
GN ORFNames=TRIATDRAFT_299508 {ECO:0000313|EMBL:EHK45960.1};
OS Hypocrea atroviridis (strain ATCC 20476 / IMI 206040) (Trichoderma
OS atroviride).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=452589 {ECO:0000313|EMBL:EHK45960.1, ECO:0000313|Proteomes:UP000005426};
RN [1] {ECO:0000313|EMBL:EHK45960.1, ECO:0000313|Proteomes:UP000005426}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 20476 / IMI 206040 {ECO:0000313|Proteomes:UP000005426};
RX PubMed=21501500; DOI=10.1186/gb-2011-12-4-r40;
RA Kubicek C.P., Herrera-Estrella A., Seidl-Seiboth V., Martinez D.A.,
RA Druzhinina I.S., Thon M., Zeilinger S., Casas-Flores S., Horwitz B.A.,
RA Mukherjee P.K., Mukherjee M., Kredics L., Alcaraz L.D., Aerts A., Antal Z.,
RA Atanasova L., Cervantes-Badillo M.G., Challacombe J., Chertkov O.,
RA McCluskey K., Coulpier F., Deshpande N., von Doehren H., Ebbole D.J.,
RA Esquivel-Naranjo E.U., Fekete E., Flipphi M., Glaser F.,
RA Gomez-Rodriguez E.Y., Gruber S., Han C., Henrissat B., Hermosa R.,
RA Hernandez-Onate M., Karaffa L., Kosti I., Le Crom S., Lindquist E.,
RA Lucas S., Luebeck M., Luebeck P.S., Margeot A., Metz B., Misra M.,
RA Nevalainen H., Omann M., Packer N., Perrone G., Uresti-Rivera E.E.,
RA Salamov A., Schmoll M., Seiboth B., Shapiro H., Sukno S.,
RA Tamayo-Ramos J.A., Tisch D., Wiest A., Wilkinson H.H., Zhang M.,
RA Coutinho P.M., Kenerley C.M., Monte E., Baker S.E., Grigoriev I.V.;
RT "Comparative genome sequence analysis underscores mycoparasitism as the
RT ancestral life style of Trichoderma.";
RL Genome Biol. 12:R40.1-R40.15(2011).
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. MetX family.
CC {ECO:0000256|ARBA:ARBA00006886}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHK45960.1}.
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DR EMBL; ABDG02000023; EHK45960.1; -; Genomic_DNA.
DR RefSeq; XP_013944170.1; XM_014088695.1.
DR AlphaFoldDB; G9NTB4; -.
DR STRING; 452589.G9NTB4; -.
DR GeneID; 25781405; -.
DR eggNOG; ENOG502QRIX; Eukaryota.
DR HOGENOM; CLU_028760_5_0_1; -.
DR OMA; SYLHYQG; -.
DR OrthoDB; 2600616at2759; -.
DR Proteomes; UP000005426; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR HAMAP; MF_00296; MetX_acyltransf; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000073; AB_hydrolase_1.
DR InterPro; IPR008220; HAT_MetX-like.
DR NCBIfam; TIGR01392; homoserO_Ac_trn; 1.
DR PANTHER; PTHR32268; HOMOSERINE O-ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR32268:SF11; HOMOSERINE O-ACETYLTRANSFERASE; 1.
DR Pfam; PF00561; Abhydrolase_1; 1.
DR PIRSF; PIRSF000443; Homoser_Ac_trans; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005426};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EHK45960.1}.
FT DOMAIN 69..439
FT /note="AB hydrolase-1"
FT /evidence="ECO:0000259|Pfam:PF00561"
FT REGION 251..340
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 293..314
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 167
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR000443-1"
FT ACT_SITE 406
FT /evidence="ECO:0000256|PIRSR:PIRSR000443-1"
FT ACT_SITE 435
FT /evidence="ECO:0000256|PIRSR:PIRSR000443-1"
SQ SEQUENCE 493 AA; 53862 MW; 352757777132872C CRC64;
MSEKNGINGD AKTIYERTQS QPENPFAALI PDQQIAIVPE FTLESGVTLY NVPVAYTTRG
KLSASGDNAM VICHALTGSA DVSDWWGPLL GGPGRAFDTS RFFIVCMNSL GSPYGSASPV
TAKDGDAKNG YYGPEFPLTT IRDDVNLHKL ILDDLGVKQV AAVIGGSLGG MFVLEWAYFG
KDYVRCVVPI ATSSRHSAWG ISWGEAQRQS IYADPKYDDG YYPFDDPPVT GLGAARMSAL
LTYRSRNSFE SRFGRNIPDP SKVQSIRERP SPSTPSEAHF HIHNDGHNVK RASTSRKNSQ
AGSGTSSPGS RSAENADPQF HGPGNDRDQG ESLTGGDKLP TSTYFSAQSY LRYQGKKFVK
RFDSNCYIAM TRKLDTHDVS RDRASSIAEA LALIEQPLLV LGIESDGLFT FAEQEEIAQY
VKNARLERID SPEGHDAFLL QFEQVNRYVL GFLKEILPDI MSVEGGAQEE EGVGQLTKSS
TFGEAEVDDI TAW
//
