ID   G9WK73_9FIRM            Unreviewed;       299 AA.
AC   G9WK73;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   13-SEP-2023, entry version 41.
DE   RecName: Full=Exonuclease domain-containing protein {ECO:0000259|SMART:SM00479};
GN   ORFNames=HMPREF9625_01780 {ECO:0000313|EMBL:EHL13715.1};
OS   Oribacterium parvum ACB1.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Oribacterium.
OX   NCBI_TaxID=796943 {ECO:0000313|EMBL:EHL13715.1, ECO:0000313|Proteomes:UP000018461};
RN   [1] {ECO:0000313|Proteomes:UP000018461}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ACB1 {ECO:0000313|Proteomes:UP000018461};
RG   The Broad Institute Genome Sequencing Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Cuomo C., Becnel J., Sanscrainte N., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA   Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA   Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA   Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA   Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA   Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RL   Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000018461}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ACB1 {ECO:0000313|Proteomes:UP000018461};
RG   The Broad Institute Genomics Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Sizova M., Hazen A.,
RA   Epstein S., Walker B., Young S., Zeng Q., Gargeya S., Fitzgerald M.,
RA   Haas B., Abouelleil A., Allen A.W., Alvarado L., Arachchi H.M.,
RA   Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A.,
RA   Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A., Larimer J.,
RA   McCowan C., Murphy C., Pearson M., Poon T.W., Priest M., Roberts A.,
RA   Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Oribacterium sp. ACB1.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EHL13715.1}.
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DR   EMBL; AFZC01000002; EHL13715.1; -; Genomic_DNA.
DR   AlphaFoldDB; G9WK73; -.
DR   STRING; 796943.HMPREF9625_01780; -.
DR   PATRIC; fig|796943.3.peg.122; -.
DR   HOGENOM; CLU_047806_3_0_9; -.
DR   Proteomes; UP000018461; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR   GO; GO:0004527; F:exonuclease activity; IEA:UniProt.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR   CDD; cd09755; Cas2_I-E; 1.
DR   CDD; cd06127; DEDDh; 1.
DR   Gene3D; 3.30.70.240; -; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR010152; CRISPR-assoc_prot_Cas2_sub.
DR   InterPro; IPR006054; DnaQ.
DR   InterPro; IPR013520; Exonuclease_RNaseT/DNA_pol3.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   NCBIfam; TIGR01873; cas_CT1978; 1.
DR   NCBIfam; TIGR00573; dnaq; 1.
DR   PANTHER; PTHR30231; DNA POLYMERASE III SUBUNIT EPSILON; 1.
DR   PANTHER; PTHR30231:SF4; PROTEIN NEN2; 1.
DR   Pfam; PF09707; Cas_Cas2CT1978; 1.
DR   Pfam; PF00929; RNase_T; 1.
DR   SMART; SM00479; EXOIII; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000018461}.
FT   DOMAIN          130..297
FT                   /note="Exonuclease"
FT                   /evidence="ECO:0000259|SMART:SM00479"
SQ   SEQUENCE   299 AA;  33874 MW;  B50EADFDF1C154A7 CRC64;
     MPMTVITLSK VSNSLKGDLS KWMQEIATGV YIGNFNSKVR DKLWERIQDA VGNGEATISY
     PMRNEIGYTF NTLNTRREIY DSDGIPLICF PLETEPEGDN EGIKEGFSNA SKYYKARKFA
     NNHSGEKKEC FAFLDLETDG LNEQCNSIIE IGAVKVMQDS GILEYHSLLE YEGELPNEIT
     GLTGITTDLL KREGRKVEIV LKEILDFLEG AIIVGYNIAF DLRFLNAILQ RNGMGILHIP
     SVDLMRIIKK EKPFQKNYKL ETSLKSYGIK KEQLHRALED AKLTYELATK VNGFCQHLP
//