ID   G9Y785_HAFAL            Unreviewed;       125 AA.
AC   G9Y785;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   RecName: Full=Dihydroneopterin triphosphate 2'-epimerase {ECO:0000256|ARBA:ARBA00044197};
DE            EC=5.1.99.7 {ECO:0000256|ARBA:ARBA00044039};
DE   AltName: Full=D-erythro-7,8-dihydroneopterin triphosphate epimerase {ECO:0000256|ARBA:ARBA00044306};
GN   ORFNames=HMPREF0454_02458 {ECO:0000313|EMBL:EHM42094.1};
OS   Hafnia alvei ATCC 51873.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Hafniaceae; Hafnia.
OX   NCBI_TaxID=1002364 {ECO:0000313|EMBL:EHM42094.1, ECO:0000313|Proteomes:UP000005959};
RN   [1] {ECO:0000313|EMBL:EHM42094.1, ECO:0000313|Proteomes:UP000005959}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51873 {ECO:0000313|EMBL:EHM42094.1,
RC   ECO:0000313|Proteomes:UP000005959};
RA   Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA   Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA   Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA   Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA   Chinwalla A., Mardis E.R., Wilson R.K.;
RL   Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=7,8-dihydroneopterin 3'-triphosphate = 7,8-dihydromonapterin
CC         3'-triphosphate; Xref=Rhea:RHEA:28346, ChEBI:CHEBI:58462,
CC         ChEBI:CHEBI:61186; EC=5.1.99.7;
CC         Evidence={ECO:0000256|ARBA:ARBA00043806};
CC   -!- SUBUNIT: Homooctamer. {ECO:0000256|ARBA:ARBA00011823}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EHM42094.1}.
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DR   EMBL; AGCI01000059; EHM42094.1; -; Genomic_DNA.
DR   RefSeq; WP_004092674.1; NZ_JH417527.1.
DR   AlphaFoldDB; G9Y785; -.
DR   GeneID; 69639285; -.
DR   PATRIC; fig|1002364.3.peg.2208; -.
DR   HOGENOM; CLU_112632_0_0_6; -.
DR   Proteomes; UP000005959; Unassembled WGS sequence.
DR   GO; GO:0004150; F:dihydroneopterin aldolase activity; IEA:InterPro.
DR   GO; GO:0006760; P:folic acid-containing compound metabolic process; IEA:InterPro.
DR   CDD; cd00534; DHNA_DHNTPE; 1.
DR   Gene3D; 3.30.1130.10; -; 1.
DR   InterPro; IPR006156; Dihydroneopterin_aldolase.
DR   InterPro; IPR006157; FolB_dom.
DR   InterPro; IPR043133; GTP-CH-I_C/QueF.
DR   NCBIfam; TIGR00526; folB_dom; 1.
DR   PANTHER; PTHR42844; DIHYDRONEOPTERIN ALDOLASE 1-RELATED; 1.
DR   PANTHER; PTHR42844:SF10; DIHYDRONEOPTERIN TRIPHOSPHATE 2'-EPIMERASE; 1.
DR   Pfam; PF02152; FolB; 1.
DR   SMART; SM00905; FolB; 1.
DR   SUPFAM; SSF55620; Tetrahydrobiopterin biosynthesis enzymes-like; 1.
PE   4: Predicted;
FT   DOMAIN          10..120
FT                   /note="Dihydroneopterin aldolase/epimerase"
FT                   /evidence="ECO:0000259|SMART:SM00905"
SQ   SEQUENCE   125 AA;  14742 MW;  25A30C88ECEDBA2C CRC64;
     MSFLQPDAII RIKNLRLRTF IGIKEEEINN KQDVVINVVI HYPAEQARRS ENIADALNYR
     TITKRIIAHV EEHRFALLEK LTQDVLDIAC EHHWVTYAEV EVDKLYALRY ADSVSMTMRY
     RKADK
//