ID G9YBN1_HAFAL Unreviewed; 757 AA.
AC G9YBN1;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=DNA internalization competence protein ComEC/Rec2-like protein {ECO:0000313|EMBL:EHM38925.1};
GN ORFNames=HMPREF0454_04060 {ECO:0000313|EMBL:EHM38925.1};
OS Hafnia alvei ATCC 51873.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Hafniaceae; Hafnia.
OX NCBI_TaxID=1002364 {ECO:0000313|EMBL:EHM38925.1, ECO:0000313|Proteomes:UP000005959};
RN [1] {ECO:0000313|EMBL:EHM38925.1, ECO:0000313|Proteomes:UP000005959}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51873 {ECO:0000313|EMBL:EHM38925.1,
RC ECO:0000313|Proteomes:UP000005959};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA Chinwalla A., Mardis E.R., Wilson R.K.;
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHM38925.1}.
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DR EMBL; AGCI01000099; EHM38925.1; -; Genomic_DNA.
DR RefSeq; WP_004095739.1; NZ_JH417552.1.
DR AlphaFoldDB; G9YBN1; -.
DR PATRIC; fig|1002364.3.peg.3652; -.
DR HOGENOM; CLU_010363_3_0_6; -.
DR Proteomes; UP000005959; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 37..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 230..250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 262..281
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 287..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 316..349
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 369..387
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 399..422
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 480..496
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 513..690
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 757 AA; 85345 MW; 5C02EDD4F20DEFE7 CRC64;
MRITLDESLQ YLAFGCVSLM FLPSIPAWPL AYGMLPVAVI IVFHHSAMVL KAALIMLGVV
WGISCAQRAL EPLQYPISHA ANYTGEVISV ALDSVSLQEK VVFRVAAING TSVRHEFDTT
LFWDSVHNPF CSGQRWSLIA NLRPVHGRLN QGGYDAQRNS VSHHIVLQGA PTAYEKLSNE
CSWRQRMISQ TLSVVPDTPS KSIIIALAFG ERALLTDSQN SLFRMSGLSH LLAISGLHIA
LAAMLGWYGA RALQLCFPLR WIHPYFPLFM MVSVGWIYVW LAGANPPAVR VGVAMVIIAG
YRCFGRFISP RKSLFNVVCL MVICEPLLLL SDSFWLSVIA VTSLLFWYWF APLPARFAIA
KRYIGLRLLH LQLGIALCLM PVQIYLFHGI SGGALWANFI AVPLVTYLVV PMILLGLVTL
WAADPFGAWY VAGFLLDRMQ WLLAYLPTLW VDMSERDIWI SLSVLMLFIA VRSFSKRGLL
FWGLVQISVF LAFVSMQKTS EDEWRVHMFD VGHGLSIAIE RQGRALLYDT GNKWERGDVA
SSEIIPYLRW HGLALDGIII SHSDSDHSGG RASLQKAFPS AWIRSPDFND FACYIGSRWQ
WQGINFTVLW PPRAISEPKN NDSCVILVER SGRKLLLTGD IEKEAEMKIV QRWREQLVAD
VLQVPHHGSN TSSSSLLLRT IKPENALSSS ARYSPWHFPS SKVVERYRRQ QVKWHDTAHS
GEVIMTAKPS GWRISELKTQ LNPRWYHGWF GVRGHNE
//
