ID H0C229_9BURK Unreviewed; 389 AA.
AC H0C229;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=glycerophosphodiester phosphodiesterase {ECO:0000256|ARBA:ARBA00012247};
DE EC=3.1.4.46 {ECO:0000256|ARBA:ARBA00012247};
GN ORFNames=KYG_18656 {ECO:0000313|EMBL:EHL21354.1};
OS Acidovorax sp. NO-1.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Acidovorax.
OX NCBI_TaxID=512030 {ECO:0000313|EMBL:EHL21354.1, ECO:0000313|Proteomes:UP000003485};
RN [1] {ECO:0000313|EMBL:EHL21354.1, ECO:0000313|Proteomes:UP000003485}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NO-1 {ECO:0000313|EMBL:EHL21354.1,
RC ECO:0000313|Proteomes:UP000003485};
RX PubMed=22374962; DOI=10.1128/JB.06814-11;
RA Huang Y., Li H., Rensing C., Zhao K., Johnstone L., Wang G.;
RT "Genome Sequence of the Facultative Anaerobic Arsenite-Oxidizing and
RT Nitrate-Reducing Bacterium Acidovorax sp. Strain NO1.";
RL J. Bacteriol. 194:1635-1636(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a sn-glycero-3-phosphodiester + H2O = an alcohol + H(+) + sn-
CC glycerol 3-phosphate; Xref=Rhea:RHEA:12969, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:30879, ChEBI:CHEBI:57597,
CC ChEBI:CHEBI:83408; EC=3.1.4.46;
CC Evidence={ECO:0000256|ARBA:ARBA00029315};
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DR EMBL; AGTS01000105; EHL21354.1; -; Genomic_DNA.
DR RefSeq; WP_008906374.1; NZ_AGTS01000105.1.
DR AlphaFoldDB; H0C229; -.
DR STRING; 512030.KYG_18656; -.
DR PATRIC; fig|512030.4.peg.3688; -.
DR OrthoDB; 9795622at2; -.
DR Proteomes; UP000003485; Unassembled WGS sequence.
DR GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd08602; GDPD_ScGlpQ1_like; 1.
DR Gene3D; 3.20.20.190; Phosphatidylinositol (PI) phosphodiesterase; 1.
DR InterPro; IPR030395; GP_PDE_dom.
DR InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR PANTHER; PTHR43620:SF7; GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE GDPD6; 1.
DR PANTHER; PTHR43620; GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE; 1.
DR Pfam; PF03009; GDPD; 1.
DR SUPFAM; SSF51695; PLC-like phosphodiesterases; 1.
DR PROSITE; PS51704; GP_PDE; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000003485};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 38..387
FT /note="GP-PDE"
FT /evidence="ECO:0000259|PROSITE:PS51704"
FT REGION 297..316
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 302..316
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 389 AA; 42552 MW; DCAE6542A723008C CRC64;
MHLSGAKLGV LAVAVGLVAC GGNDDDSSRY STLNGDKPLV IGHRGASGYL PEHTLESYKR
AIELGADFIE PDLVATKDGV LVARHEPNIT GTTDVSTRPE FADRKTKKVV DGVEEEGWFA
SDFTLAEIKT LRAIQPMAER DQSYNGKFQI PTLDEVLDLA KSEGAKTNRT VGVYPETKHP
TYHVNLGLQL EDRLLAALAK YGYTSKASPV IVQSFEVSNL KYLRTKTQIR LVQLVDANDV
NPNGTVDLTA PYDKPYDFAV AGDARTFASL LTPAGLKEVK TYADGIGPWK PYLIPSRQVD
ANNDGKPDDL NNDGKIDDRD RVMMPATDVV KNAHAVGLMV HPYTFRSEAR RLASDFKGDP
KAEYKLFYEL GVDGVFSDFP DAAKAARDN
//
