ID H0C3Q0_9BURK Unreviewed; 302 AA.
AC H0C3Q0;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Pyruvate carboxyltransferase {ECO:0000313|EMBL:EHL20737.1};
GN ORFNames=KYG_21204 {ECO:0000313|EMBL:EHL20737.1};
OS Acidovorax sp. NO-1.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Acidovorax.
OX NCBI_TaxID=512030 {ECO:0000313|EMBL:EHL20737.1, ECO:0000313|Proteomes:UP000003485};
RN [1] {ECO:0000313|EMBL:EHL20737.1, ECO:0000313|Proteomes:UP000003485}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NO-1 {ECO:0000313|EMBL:EHL20737.1,
RC ECO:0000313|Proteomes:UP000003485};
RX PubMed=22374962; DOI=10.1128/JB.06814-11;
RA Huang Y., Li H., Rensing C., Zhao K., Johnstone L., Wang G.;
RT "Genome Sequence of the Facultative Anaerobic Arsenite-Oxidizing and
RT Nitrate-Reducing Bacterium Acidovorax sp. Strain NO1.";
RL J. Bacteriol. 194:1635-1636(2012).
CC -!- SIMILARITY: Belongs to the HMG-CoA lyase family.
CC {ECO:0000256|ARBA:ARBA00009405}.
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DR EMBL; AGTS01000145; EHL20737.1; -; Genomic_DNA.
DR AlphaFoldDB; H0C3Q0; -.
DR STRING; 512030.KYG_21204; -.
DR PATRIC; fig|512030.4.peg.4172; -.
DR Proteomes; UP000003485; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016833; F:oxo-acid-lyase activity; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR CDD; cd07938; DRE_TIM_HMGL; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR043594; HMGL.
DR InterPro; IPR000891; PYR_CT.
DR PANTHER; PTHR42738; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR PANTHER; PTHR42738:SF7; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR Pfam; PF00682; HMGL-like; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR PROSITE; PS50991; PYR_CT; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Pyruvate {ECO:0000313|EMBL:EHL20737.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000003485};
KW Transferase {ECO:0000313|EMBL:EHL20737.1}.
FT DOMAIN 1..268
FT /note="Pyruvate carboxyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS50991"
SQ SEQUENCE 302 AA; 32279 MW; 428FDE3B168BA4BF CRC64;
MKIVEVGPRD GLQNEGKIVP TAMKLDLIER LVKAGLKNIE ATSFVSPKWV PQMGDHLQIM
SGLPQYPGVF YSVLTPNLKG FEAAAQSGAT EVAVFAAASE AFSARNINCS IAESLERFEP
VMQSAQSLGI KVRGYVSCVV GCPYEGKVDP ERVADVAERL FNMGCYEVSL GDTIGIGTPV
DVQKVLESVA RRVPVHALAG HFHDTYGRAL MNIYASYQFG VRVFDSSVSG LGGCPYAKGA
SGNVATEDVV FLMNSLGAHT GVDLEKLVDV SAWISTLLHR TPNSKVIGPV LAKRASEVLC
IS
//
