ID H0E2V8_9ACTN Unreviewed; 496 AA.
AC H0E2V8;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Aldehyde dehydrogenase {ECO:0000313|EMBL:EHN11975.1};
DE EC=1.2.1.3 {ECO:0000313|EMBL:EHN11975.1};
GN ORFNames=PAI11_11230 {ECO:0000313|EMBL:EHN11975.1};
OS Patulibacter medicamentivorans.
OC Bacteria; Actinomycetota; Thermoleophilia; Solirubrobacterales;
OC Patulibacteraceae; Patulibacter.
OX NCBI_TaxID=1097667 {ECO:0000313|EMBL:EHN11975.1, ECO:0000313|Proteomes:UP000005143};
RN [1] {ECO:0000313|EMBL:EHN11975.1, ECO:0000313|Proteomes:UP000005143}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=I11 {ECO:0000313|EMBL:EHN11975.1,
RC ECO:0000313|Proteomes:UP000005143};
RX PubMed=23212173; DOI=10.1007/s10532-012-9610-5;
RA Almeida B., Kjeldal H., Lolas I., Knudsen A.D., Carvalho G., Nielsen K.L.,
RA Barreto Crespo M.T., Stensballe A., Nielsen J.L.;
RT "Quantitative proteomic analysis of ibuprofen-degrading Patulibacter sp.
RT strain I11.";
RL Biodegradation 24:615-630(2013).
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHN11975.1}.
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DR EMBL; AGUD01000052; EHN11975.1; -; Genomic_DNA.
DR AlphaFoldDB; H0E2V8; -.
DR OrthoDB; 6882680at2; -.
DR Proteomes; UP000005143; Unassembled WGS sequence.
DR GO; GO:0004029; F:aldehyde dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0043878; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity; IEA:UniProtKB-EC.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000005143}.
FT DOMAIN 18..491
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 253
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 496 AA; 51829 MW; 62A8947FF46D06AD CRC64;
MSTTTEQAAA TLLIDGQWRD AAEHYERVDP ADPSRVTGRY AAATAADVGD AYAAAARAQV
AWAARPVTDR EAILRRAGDL LEQRVEAATA ALVDDIGKAH RDARGEVLRG AAILRFHAGA
VLQASGETYD GADPSTLLLT LSEPVGVVGA ITPWNFPVAI PLWKLAPALA YGNAVVWKPA
EAASGSAVLL ARLLSEAGLP DGVLNLVTGS GRALSEPLTK DPALAALTFT GSVGVGLRLR
AALADRTTKL QLELGGKNPA IVLADADLPD AIEQIARGAM LQAGQRCTAT SRVYVDRGIH
DAFVAGLVER VRAFAVGDPR DPATDIGPLA SREQRDTVEG YLAQARDGAA TIACGGSPIA
DGDGAAWKGD GRAAGGHWVQ PTVLTDVADD HPLVREEIFG PVVCVTAVDG FDDALARAND
SEFGLSSAVF TRDLATALRF ARGTRSGLVH VNRETAGVEP HLPFGGVKAS SSMNREQGMA
ARDFFSVTKT VYIRPR
//
