ID H0EVA9_GLAL7 Unreviewed; 391 AA.
AC H0EVA9;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Putative Betaine aldehyde dehydrogenase, chloroplastic {ECO:0000313|EMBL:EHK97551.1};
GN ORFNames=M7I_6704 {ECO:0000313|EMBL:EHK97551.1};
OS Glarea lozoyensis (strain ATCC 74030 / MF5533).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Helotiaceae; Glarea.
OX NCBI_TaxID=1104152 {ECO:0000313|EMBL:EHK97551.1, ECO:0000313|Proteomes:UP000005446};
RN [1] {ECO:0000313|EMBL:EHK97551.1, ECO:0000313|Proteomes:UP000005446}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 74030 / MF5533 {ECO:0000313|Proteomes:UP000005446};
RX PubMed=22302591; DOI=10.1128/EC.05302-11;
RA Youssar L., Gruening B.A., Erxleben A., Guenther S., Huettel W.;
RT "Genome sequence of the fungus Glarea lozoyensis: the first genome sequence
RT of a species from the Helotiaceae family.";
RL Eukaryot. Cell 11:250-250(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=an aldehyde + H2O + NAD(+) = a carboxylate + 2 H(+) + NADH;
CC Xref=Rhea:RHEA:16185, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:17478, ChEBI:CHEBI:29067, ChEBI:CHEBI:57540,
CC ChEBI:CHEBI:57945; EC=1.2.1.3;
CC Evidence={ECO:0000256|ARBA:ARBA00024149};
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|RuleBase:RU003345}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHK97551.1}.
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DR EMBL; AGUE01000189; EHK97551.1; -; Genomic_DNA.
DR AlphaFoldDB; H0EVA9; -.
DR HOGENOM; CLU_005391_0_0_1; -.
DR InParanoid; H0EVA9; -.
DR Proteomes; UP000005446; Unassembled WGS sequence.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR11699:SF263; ALDEHYDE DEHYDROGENASE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00171; Aldedh; 2.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000005446}.
FT DOMAIN 30..102
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT DOMAIN 105..379
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 158
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 391 AA; 42956 MW; 63E885D4854A116F CRC64;
MNGTKETPIE FEKFHNIVDG LPRSSTNFHR GTNPSDGKEL WEVPIASEND LDDAVEAARK
AFKTWSKTKW EDRQEIIKNI AKEFMKYEAE MGKLVMLEGG KPKFLPPGVL QALNGDDKLG
PLMTEHPGIN MITFTGSTPT GKRVMASCAK TLKRVTLELG GNSAAIICPD VDVNKVAPKV
ALAAFFNSGQ ICVASKRLYV HKDIYADMLA AVKKVVEGWK TAPAVEEGTM LGPVQNKMQH
AIVKDFFEDC ASQGYDFALQ GEVGKGEGFV VQPAIIDNPP DDSRIVREEQ FGPIVPMLQW
EDEDEVIARV NDTTTGLGGA VYCADLDRAQ RLASRIEAGN IWINSNEKPL PNAFFSGWKE
SGIGGESGRL GLYNYMNTQV THLYKADVAK L
//
