ID H0FTP9_RHIML Unreviewed; 337 AA.
AC H0FTP9;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=RND family efflux transporter MFP subunit {ECO:0008006|Google:ProtNLM};
GN ORFNames=SM0020_02590 {ECO:0000313|EMBL:EHK79587.1};
OS Sinorhizobium meliloti CCNWSX0020.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX NCBI_TaxID=1107881 {ECO:0000313|EMBL:EHK79587.1, ECO:0000313|Proteomes:UP000004038};
RN [1] {ECO:0000313|EMBL:EHK79587.1, ECO:0000313|Proteomes:UP000004038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCNWSX0020 {ECO:0000313|EMBL:EHK79587.1,
RC ECO:0000313|Proteomes:UP000004038};
RX PubMed=22328762; DOI=10.1128/JB.06682-11;
RA Li Z., Ma Z., Hao X., Wei G.;
RT "Draft Genome Sequence of Sinorhizobium meliloti CCNWSX0020, a Nitrogen-
RT Fixing Symbiont with Copper Tolerance Capability Isolated from Lead-Zinc
RT Mine Tailings.";
RL J. Bacteriol. 194:1267-1268(2012).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AGVV01000003; EHK79587.1; -; Genomic_DNA.
DR AlphaFoldDB; H0FTP9; -.
DR PATRIC; fig|1107881.3.peg.530; -.
DR Proteomes; UP000004038; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0042221; P:response to chemical; IEA:UniProt.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR043602; CusB_dom_1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF33; EFFLUX PROTEIN; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF00529; CusB_dom_1; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}.
FT DOMAIN 18..261
FT /note="Cation efflux system protein CusB"
FT /evidence="ECO:0000259|Pfam:PF00529"
FT DOMAIN 58..253
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT COILED 96..147
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 337 AA; 36507 MW; 8EA4B08D363EA1B2 CRC64;
MQQMRRYAAG IAIAAAVGAV AFWHATRAVP VSIVTPKRGD AAEIVYASGV VEPRVWAKVT
STVRERIVEQ CNCEGERVEK GAVLARLDDT EARAILSELQ ARLSLAQEEY RRKLALAERN
TISEQTVDRA RTDVAQLEAL IAGQEARLAA YVLRAPSDGR VLRQDGEIGE VAEPGTVLFW
VGEPRPLIVE AEVNEEDIPR VEVGQNAYLR SDAFPERALE AVVDSITPKG DPVTKTYRVR
LRLPEDTPLR IGMSTDVNVV VRLSRNALVI PAAAVSGTRV AVVEGGTAKL REIETGIRGT
DGVEVLSGLE ETARIISPLS PDFADGTRVD VVQTATN
//
