ID H0G6R9_RHIML Unreviewed; 1092 AA.
AC H0G6R9;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Adenylate/guanylate cyclase {ECO:0000313|EMBL:EHK75033.1};
GN ORFNames=SM0020_25986 {ECO:0000313|EMBL:EHK75033.1};
OS Sinorhizobium meliloti CCNWSX0020.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX NCBI_TaxID=1107881 {ECO:0000313|EMBL:EHK75033.1, ECO:0000313|Proteomes:UP000004038};
RN [1] {ECO:0000313|EMBL:EHK75033.1, ECO:0000313|Proteomes:UP000004038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCNWSX0020 {ECO:0000313|EMBL:EHK75033.1,
RC ECO:0000313|Proteomes:UP000004038};
RX PubMed=22328762; DOI=10.1128/JB.06682-11;
RA Li Z., Ma Z., Hao X., Wei G.;
RT "Draft Genome Sequence of Sinorhizobium meliloti CCNWSX0020, a Nitrogen-
RT Fixing Symbiont with Copper Tolerance Capability Isolated from Lead-Zinc
RT Mine Tailings.";
RL J. Bacteriol. 194:1267-1268(2012).
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DR EMBL; AGVV01000070; EHK75033.1; -; Genomic_DNA.
DR RefSeq; WP_003533774.1; NZ_AGVV01000070.1.
DR AlphaFoldDB; H0G6R9; -.
DR PATRIC; fig|1107881.3.peg.5262; -.
DR Proteomes; UP000004038; Unassembled WGS sequence.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR CDD; cd09487; SAM_superfamily; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR16305:SF28; ADENYLATE CYCLASE 10; 1.
DR PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR Pfam; PF00536; SAM_1; 1.
DR SMART; SM00044; CYCc; 1.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
PE 4: Predicted;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 1..61
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 71..200
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
SQ SEQUENCE 1092 AA; 121175 MW; 9585EBA61CB06E37 CRC64;
MDDVAKWLGG LGLQQFVSTF ALFQLDFDAL RSLSDQELQE MQIPPGPRKK ILAAIKLLNE
ADRPPERRQI TLLFCDLVNS TEYAVRLEPE DFQILTETYL QRCTNIVRSR SGMIVNYSGD
ALLALFGYPF TEEDDADRAV QAALDIVQIA PSIDVSGGPP VQVRIGVASG LAVVAKLLGA
SKGGPPVPYG PLPSLAQRLQ ALALPQTVLT DQHTYNATTG AFEFTDIGLH SLKGLPELRV
WRVERPRILE SRFAKKTRLF RLVARSAQLR KLVTHWDKVV AERRGRVVFL SGEPGIGKSR
LAFEVQQRIA RCTHLSLQCS ATFSNSAFYP FLNLLKRYAG IRDGDPPHVT RSRLETILAT
SSVSKEVSLP IFERLLSIPQ VPVPQPGPAP VELSSGRQQA ISRRVLVDWL HHVAQLNPVL
ATFEDEQWID PSSRDVLDVL INEAFSHPML ILVTSRGKSA ETGRKARHVF EMQLKRLSRR
ESQTLVHDVA AGANLPEEVR ARVLNKAEGV PLYVEELTRA AMETGLPHDP QEQEAPKSDI
RVPRVLQLSL LSRLDKLGSG KVISQVAAVI GREFDLKLLA HLCGLSRRAL GSAIVRLTEA
GLVAPQLFAN RSSYAFTHAL LQEAARSTLV RERRQELHRL VAQAIESLDP KNAAEHPELL
AQHFAEAGMF ERAADCWLSA GRNVAKTWAK VEAANMFAMG LACLERLPVS RMRSEKALRF
ELERGDVLYA TFGYVTREGS TAYRNAMRLS EELGDSEALI SALDGLFGTA FNSARFTDAE
WASDQLIEIG RKSDSLRARV LGLQFKGMSI FCGGNFRGAR RYLERSLGYE AQAKLIGSDF
PSMAYLYLSW TMHLLGHPRQ ALEQYSKAEA VTRRQAAARV ERWEYRLSAC LGNGCILLAL
QNNTAKLKEA TEELVPLAHD HGLNLWENMG NFFTAWAMES ASHDPAGLQS MQTVCDRLGE
QKIDKSCYLG LLASAYIQSG NLGKAVAAIE QGLEHAASTG EYYFAAELTR LRGEVQLQLK
DDPVGAEASF REAINIAREQ GAKTWEIKAT QSLASLWDTL GRQFKIDSDL ELVPAELKRR
PRGRRPFTSR LA
//
