ID H0G7B9_RHIML Unreviewed; 181 AA.
AC H0G7B9;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Hydroxylysine kinase {ECO:0000256|ARBA:ARBA00040505};
DE EC=2.7.1.81 {ECO:0000256|ARBA:ARBA00038873};
GN ORFNames=SM0020_27006 {ECO:0000313|EMBL:EHK74760.1};
OS Sinorhizobium meliloti CCNWSX0020.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX NCBI_TaxID=1107881 {ECO:0000313|EMBL:EHK74760.1, ECO:0000313|Proteomes:UP000004038};
RN [1] {ECO:0000313|EMBL:EHK74760.1, ECO:0000313|Proteomes:UP000004038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCNWSX0020 {ECO:0000313|EMBL:EHK74760.1,
RC ECO:0000313|Proteomes:UP000004038};
RX PubMed=22328762; DOI=10.1128/JB.06682-11;
RA Li Z., Ma Z., Hao X., Wei G.;
RT "Draft Genome Sequence of Sinorhizobium meliloti CCNWSX0020, a Nitrogen-
RT Fixing Symbiont with Copper Tolerance Capability Isolated from Lead-Zinc
RT Mine Tailings.";
RL J. Bacteriol. 194:1267-1268(2012).
CC -!- FUNCTION: Catalyzes the GTP-dependent phosphorylation of 5-hydroxy-L-
CC lysine. {ECO:0000256|ARBA:ARBA00037368}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(5R)-5-hydroxy-L-lysine + GTP = (5R)-5-phosphooxy-L-lysine +
CC GDP + H(+); Xref=Rhea:RHEA:19049, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:37565, ChEBI:CHEBI:57882, ChEBI:CHEBI:58189,
CC ChEBI:CHEBI:58357; EC=2.7.1.81;
CC Evidence={ECO:0000256|ARBA:ARBA00036820};
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DR EMBL; AGVV01000077; EHK74760.1; -; Genomic_DNA.
DR AlphaFoldDB; H0G7B9; -.
DR PATRIC; fig|1107881.3.peg.5476; -.
DR Proteomes; UP000004038; Unassembled WGS sequence.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.90.1200.10; -; 1.
DR InterPro; IPR002575; Aminoglycoside_PTrfase.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR PANTHER; PTHR21064:SF1; HYDROXYLYSINE KINASE; 1.
DR PANTHER; PTHR21064; UNCHARACTERIZED; 1.
DR Pfam; PF01636; APH; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Transferase {ECO:0000313|EMBL:EHK74760.1}.
FT DOMAIN 12..107
FT /note="Aminoglycoside phosphotransferase"
FT /evidence="ECO:0000259|Pfam:PF01636"
SQ SEQUENCE 181 AA; 20000 MW; EFC72A81BB95DDE7 CRC64;
MSHTLDLAAV VDHVAPERRA QAEAVLAEFE RALPAITGLK RRQIIHNDFN PHNVLLDPAA
PTTVVGVIDF GDMVHAPLIN DLAVALSYHL ATANWAARTG AFLEGFLSAR ALEPDEIEVL
PVLTRARLAM SLIIAEWRSA RFPENRDYIM RNHATAWRGL QNISDLTPAG LKKLVPNLYE
V
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