ID H0R498_9ACTN Unreviewed; 920 AA.
AC H0R498;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE RecName: Full=VWFA domain-containing protein {ECO:0000259|PROSITE:PS50234};
GN ORFNames=GOEFS_096_00760 {ECO:0000313|EMBL:GAB19899.1};
OS Gordonia effusa NBRC 100432.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC Gordonia.
OX NCBI_TaxID=1077974 {ECO:0000313|EMBL:GAB19899.1, ECO:0000313|Proteomes:UP000035034};
RN [1] {ECO:0000313|EMBL:GAB19899.1, ECO:0000313|Proteomes:UP000035034}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 100432 {ECO:0000313|EMBL:GAB19899.1,
RC ECO:0000313|Proteomes:UP000035034};
RA Yoshida I., Takarada H., Hosoyama A., Tsuchikane K., Katsumata H.,
RA Yamazaki S., Fujita N.;
RT "Whole genome shotgun sequence of Gordonia effusa NBRC 100432.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAB19899.1}.
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DR EMBL; BAEH01000096; GAB19899.1; -; Genomic_DNA.
DR RefSeq; WP_007319234.1; NZ_BAEH01000096.1.
DR AlphaFoldDB; H0R498; -.
DR STRING; 1077974.GOEFS_096_00760; -.
DR eggNOG; ENOG502Z9PW; Bacteria.
DR OrthoDB; 4424690at2; -.
DR Proteomes; UP000035034; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR Pfam; PF13519; VWA_2; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000035034};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..33
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 34..920
FT /note="VWFA domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003538147"
FT TRANSMEM 667..690
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 54..290
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 850..920
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 872..908
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 920 AA; 94522 MW; 4B78A215A33F4FAE CRC64;
MTITHVARRV SALLAVLAVV ALASMPLLPT ANAATGDEGV DRFGACLAAN KSGQVLFLMD
ESFSLRESDP QAARVTASKY LAEQLQTFAA DTGAKLDVAV SSFAANYREL NDWQQLSSST
VTSITDTLGS LQNQNSGQDT DYWAALTGAQ KTLAKRKPAN GASGCQMVAW FTDGALDFNV
HNRTEDKTKE YAPGVELNGP DDAAKVSAAA KESICRSGGV ADQLRSSGVI TIGIGLDSAG
ASASTFDLMK SIATGQTTST GKCGDITSPV PGGFYPVSDI DDLLFAFDRL STPGQPPIPK
TAGACARTVC EKGKHKFVLD RSVGSVAILA SADRTGLVPV LVAPNGSQTR MVSGSPGSAD
VNGVKITYRD PSSKTVSVRM TNRDAAGWRG VWALVYIAPD GDAAAKTRSS IHITGDLLPA
WPAQNTTKLH SGDTSVDMTF AVKQTNGTTI DAADIPGKAA LSAQLVTAAG KTISITTSDL
DKAHITDKQT FSLAGVAPGN ATLRMTLKVT TAPARESNGT LVPGTVLSPQ NVDLPVTIAA
PVGYPQLSSS IDFGTVEAAG SKTAAVKITG PGCVWRNASS SPTILGSPDG AGTPTVDASA
NAKANCVTVA EGRSGELPLT LTVPNDANGT LNGTVSIMVA PTDGSAPPVE VRVPFTASLQ
KNLDVPLTVG VFIAALILGP LIPLLLLYLV KWFTARIPAK ALRSEQIRVQ VNGNAVLRDG
APFALRDTDL VRMVPGLDKP ARDLDLGGGV RLRARIGLAP FGTGFVVATA PGSAGAAGKT
GATHGKTPDA KLPLAVHNSW FVLHDPNGPA NAATVVVLAG ADATPAVRNR IDAEIASTLP
RILGELRTKA AGAQPNPPGT SGPDGGQSNP FGGGQPPPPL TNPFAGPPTT GNPFGPPQRP
PHGPYQGPPQ GGQYPRNPYQ
//
