ID H0V963_CAVPO Unreviewed; 456 AA.
AC H0V963;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=Glycosyltransferase-like domain-containing protein 1 {ECO:0000256|ARBA:ARBA00018379};
GN Name=GTDC1 {ECO:0000313|Ensembl:ENSCPOP00000006341.2};
OS Cavia porcellus (Guinea pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae;
OC Cavia.
OX NCBI_TaxID=10141 {ECO:0000313|Ensembl:ENSCPOP00000006341.2, ECO:0000313|Proteomes:UP000005447};
RN [1] {ECO:0000313|Proteomes:UP000005447}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2N {ECO:0000313|Proteomes:UP000005447};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSCPOP00000006341.2}
RP IDENTIFICATION.
RC STRAIN=2N {ECO:0000313|Ensembl:ENSCPOP00000006341.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the glycosyltransferase group 1 family.
CC Glycosyltransferase 4 subfamily. {ECO:0000256|ARBA:ARBA00009481}.
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DR EMBL; AAKN02006308; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAKN02006309; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAKN02006310; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAKN02006311; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAKN02006312; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAKN02006313; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAKN02006314; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAKN02006315; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAKN02006316; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAKN02006317; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003478757.1; XM_003478709.3.
DR RefSeq; XP_012998092.1; XM_013142638.1.
DR AlphaFoldDB; H0V963; -.
DR STRING; 10141.ENSCPOP00000006341; -.
DR Ensembl; ENSCPOT00000007099.3; ENSCPOP00000006341.2; ENSCPOG00000007030.4.
DR GeneID; 100728290; -.
DR KEGG; cpoc:100728290; -.
DR CTD; 79712; -.
DR VEuPathDB; HostDB:ENSCPOG00000007030; -.
DR eggNOG; ENOG502QQJ3; Eukaryota.
DR GeneTree; ENSGT00390000006631; -.
DR HOGENOM; CLU_033439_1_0_1; -.
DR InParanoid; H0V963; -.
DR OMA; HRWEYDK; -.
DR OrthoDB; 5399874at2759; -.
DR TreeFam; TF324818; -.
DR Proteomes; UP000005447; Unassembled WGS sequence.
DR Bgee; ENSCPOG00000007030; Expressed in ovary and 13 other cell types or tissues.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:InterPro.
DR CDD; cd01635; Glycosyltransferase_GTB-type; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 1.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR022701; GlycosylTrfase_1_N.
DR PANTHER; PTHR13615; GLYCOSYLTRANSFERASE-LIKE 1; 1.
DR PANTHER; PTHR13615:SF3; GLYCOSYLTRANSFERASE-LIKE DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF12038; DUF3524; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005447}.
FT DOMAIN 2..167
FT /note="Glycosyltransferase family 1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12038"
FT DOMAIN 284..419
FT /note="Glycosyl transferase family 1"
FT /evidence="ECO:0000259|Pfam:PF00534"
SQ SEQUENCE 456 AA; 52519 MW; 33AE7C025D23E562 CRC64;
MSILIIEAFY GGSHKELVDL LQNELQNCVL YTLPAKKWHW RARTAALYFS QNIPISEHYR
VLFASSVLNL TELVALRPDL GKLKKILYFH ENQLVYPVKK YQERDFQYGY NQILSCLVAD
VVVFNSVFNM ESFLTSIGKF MKLIPDHRPK DLESIIRPKC QVIYFPIMFP DVSRFMPEHK
ITHLKKMLSL KGNGSPALSM ALPSQPEQRT PEDLLENFNI VYNVHSDLHT AQENLDNSSI
QGSDLKHTNS SDNSRFLHGE NTHLTLSSFD SLGGVDDQQR PLHIVWPHRW EHDKDPESFF
KVLMHLKNLG LDFHVSVLGE TFTDVPGIFS EAKKALGSSI LHWGYLSCKD DYFQVLCMAD
VVISTAKHEF FGVAMLEAVY CGCYPLCPKD LVYPEIFPAE YLYSTPEQLS KKLQNFCKRP
DIIRKHLYKG EMAPFSWAAL RSKFRSLLTT EPREDL
//
