ID   H0WQ30_OTOGA            Unreviewed;       783 AA.
AC   H0WQ30;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   SubName: Full=Death domain containing 1 {ECO:0000313|Ensembl:ENSOGAP00000004038.2};
GN   Name=DTHD1 {ECO:0000313|Ensembl:ENSOGAP00000004038.2};
OS   Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC   Galagidae; Otolemur.
OX   NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000004038.2, ECO:0000313|Proteomes:UP000005225};
RN   [1] {ECO:0000313|Proteomes:UP000005225}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Sequencing Platform;
RA   Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA   Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA   Walker B.J., Sharpe T., Hall G.;
RT   "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL   Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSOGAP00000004038.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AAQR03173573; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03173574; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03173575; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03173576; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03173577; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03173578; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03173579; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03173580; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03173581; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03173582; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; H0WQ30; -.
DR   STRING; 30611.ENSOGAP00000004038; -.
DR   Ensembl; ENSOGAT00000004524.2; ENSOGAP00000004038.2; ENSOGAG00000004522.2.
DR   eggNOG; ENOG502QTTM; Eukaryota.
DR   GeneTree; ENSGT00940000153404; -.
DR   HOGENOM; CLU_013631_0_0_1; -.
DR   InParanoid; H0WQ30; -.
DR   OMA; HYQLPIC; -.
DR   TreeFam; TF351910; -.
DR   Proteomes; UP000005225; Unassembled WGS sequence.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 2.60.220.30; -; 1.
DR   Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR000488; Death_domain.
DR   InterPro; IPR000906; ZU5_dom.
DR   PANTHER; PTHR28336; BA1-643; 1.
DR   PANTHER; PTHR28336:SF4; DEATH DOMAIN-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF00531; Death; 1.
DR   SUPFAM; SSF47986; DEATH domain; 1.
DR   PROSITE; PS50017; DEATH_DOMAIN; 1.
DR   PROSITE; PS51145; ZU5; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000005225}.
FT   DOMAIN          302..484
FT                   /note="ZU5"
FT                   /evidence="ECO:0000259|PROSITE:PS51145"
FT   DOMAIN          699..763
FT                   /note="Death"
FT                   /evidence="ECO:0000259|PROSITE:PS50017"
SQ   SEQUENCE   783 AA;  88174 MW;  23A4CA6AB985C88D CRC64;
     LHDESSLQQT MSTIQDTKPT DIAAKRELNV IETATVSATN AEESHQTHQV LLGKNTTRAS
     SELVGEGDQA PLSGSVMGQE ESQHKMFPDN TENEGDKQIK HVTAESISSN KEEIHGIIRT
     TEIEIEKTTE SPREEMTTST VTCSIGNTHV NSCLPNDSEN IKQKDNIMEK EYFDVLSDGT
     DPQVSCYITA PLYVLQQLKC RIINHMSSLI VSDYEELVSN VITIECSDGE NKIPFPICIA
     IPFTAHYRGN YREIMVKVCD VHLQSSYLNP NSLEGVTGSS QGNCAAVKIY KLGIFSVVSC
     LKKESFIVTK KGLTFKSNVD SRISLNYSPG VFSSPVLIQL KIQPVDPSLV AYLKAQQDTF
     YSVLSTSPLV HVQHPSTHPF QKPVTVFLPC SPHPDKKNLG SEIDQKRTTS TTTNRITPSY
     FNWTKSTSIR KTGKNASETL KLLGFRSQDS GWFGVDDVVV RAIQSGLISF ELNEHLERFI
     VVHLSSVVDN RHLVTFVRSL EEALLSTTAC IVLSHQKNEP HRIAVSVVPS KDLNQALKNL
     HLEGFGGPPE PSQHFQVREG EQLLLRFTGN IFASSNGKDY GKDYKLIFHL QRKPRLKLQI
     KEVDEFGNYS CPHYKGTIVV YKVPKEKIVP NLDQSLIIYE TSGLLICKLS LRLPKHKKLI
     NRPQSTKRIS TDPTEALWDN MLHWLAEELS EEEEQAEALS SSLPLRRSTI QLLKLKNPDD
     LTEQIHELLC FWKKSLPTST DKLRLLARHL RKIGRRDLAE VLRFKWENKV FTEPQQWLHP
     AAE
//