ID H0WSV2_OTOGA Unreviewed; 852 AA.
AC H0WSV2;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Integrator complex subunit 6 {ECO:0000313|Ensembl:ENSOGAP00000005183.2};
GN Name=INTS6 {ECO:0000313|Ensembl:ENSOGAP00000005183.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000005183.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000005183.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAQR03165134; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03165135; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03165136; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0WSV2; -.
DR STRING; 30611.ENSOGAP00000005183; -.
DR Ensembl; ENSOGAT00000005798.2; ENSOGAP00000005183.2; ENSOGAG00000005794.2.
DR eggNOG; KOG3768; Eukaryota.
DR GeneTree; ENSGT00390000016655; -.
DR HOGENOM; CLU_006789_0_0_1; -.
DR InParanoid; H0WSV2; -.
DR OMA; DFTLPMH; -.
DR TreeFam; TF323386; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0015629; C:actin cytoskeleton; IEA:Ensembl.
DR GO; GO:0032039; C:integrator complex; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0016180; P:snRNA processing; IEA:Ensembl.
DR CDD; cd00198; vWFA; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR029307; INT_SG_DDX_CT_C.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR12957; DEAD/H BOX POLYPEPTIDE 26/DICE1-RELATED; 1.
DR PANTHER; PTHR12957:SF23; INTEGRATOR COMPLEX SUBUNIT 6; 1.
DR Pfam; PF15300; INT_SG_DDX_CT_C; 1.
DR Pfam; PF13519; VWA_2; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005225}.
FT DOMAIN 3..227
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 633..666
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 736..768
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 852 AA; 96154 MW; FC2EF0E5E73A8A05 CRC64;
MPILLFLIDT SASMNQRSHL GTTYLDTAKG AVETFMKLRA RDPASRGDRY MLVTFEEPPY
AIKAGWKENH ATFMNELKNL QAEGLTTLGQ SLRTAFDLLN LNRLVTGIDN YGQGRNPFFL
EPAIIITITD GSKLTTTSGV QDELHLPLNS PLPGSELTKE PFRWDQRLFA LVLRLPGTMS
VESEQLTGVP LDDSAITPMC EVTGGRSYSV CSPRMLNQCL ESLVQKVQSG VVINFEKAGP
DPSPVEDGQP DISRPFGSQP WHSCHKLIYV RPNPKTGVPI GHWPVPESFW PDQNSPTLPP
RTSHPVVKFS CTDCEPMVID KLPFDKYELE PSPLTQFILE RKSPQTCWQV YVSNSAKYSE
LGHPFGYLKA STALNCVNLF VMPYNYPVLL PLLDDLFKVH KAKPTLKWRQ SFESYLKTMP
PYYLGAKIES DRVIGSVGKK VVQETGIKVR SRSHGLSMAY RKDFQQLLQG ISEDVPHRLL
DLNMKEYTGF QVALLNKDLK PQTFRNAYDI PRRNLLDHLT RMRSNLLKST RRFLKGQDED
QVHSVPIAQM GNYQEYLKQV PSPLRELDPD QPRRLHTFGN PFKLDKKGMM IDEADEFVAG
PQNKHKRPGE PNMQGIPKRR RCMSPLLRGR QQNPVVNNHI GGKGPPAPGA QAQPDLSKPL
PLHKKTTNDS TIIDDVVENH VVDQLSSDIA PNAMGAEFST SSPASLLERP TNHTEALGHD
HLGTNDLHVS GFLENHEEPR GKEQCVEESM PAASLSKGKK STHCRSHEEV NTELKAQIMK
EIRKPGRKYE RIFTLLKHVQ GSLQTRLIFL QNVIKEASRF KKRMLIEQLE NFLDEIHRRA
SQINHVNSNI SC
//
