ID H0WUZ3_OTOGA Unreviewed; 437 AA.
AC H0WUZ3;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Ring finger protein 150 {ECO:0000313|Ensembl:ENSOGAP00000006099.2};
GN Name=RNF150 {ECO:0000313|Ensembl:ENSOGAP00000006099.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000006099.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000006099.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAQR03074158; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03074159; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03074160; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03074161; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03074162; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03074163; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03074164; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03074165; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03074166; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03074167; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003790231.1; XM_003790183.2.
DR AlphaFoldDB; H0WUZ3; -.
DR STRING; 30611.ENSOGAP00000006099; -.
DR Ensembl; ENSOGAT00000006819.2; ENSOGAP00000006099.2; ENSOGAG00000006816.2.
DR GeneID; 100947457; -.
DR KEGG; oga:100947457; -.
DR CTD; 57484; -.
DR eggNOG; KOG0800; Eukaryota.
DR GeneTree; ENSGT00940000156171; -.
DR HOGENOM; CLU_049885_2_1_1; -.
DR InParanoid; H0WUZ3; -.
DR OMA; VNITYMD; -.
DR OrthoDB; 5474929at2759; -.
DR TreeFam; TF317486; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd02122; PA_GRAIL_like; 1.
DR CDD; cd16805; RING-H2_RNF150; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46539; E3 UBIQUITIN-PROTEIN LIGASE ATL42; 1.
DR PANTHER; PTHR46539:SF25; RING FINGER PROTEIN 150; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF13639; zf-RING_2; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT SIGNAL 1..34
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 35..437
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003544017"
FT TRANSMEM 208..231
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 277..318
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
SQ SEQUENCE 437 AA; 48013 MW; E7788FAA46D5A6D6 CRC64;
MAMSLIRACR SLALSTWLLS FCFVHLLCLD FTVAEKEEWY TAFVNITYAE SAPDPGAGGT
GGGAELHTEK TECGRYGEHS PKQDARGEVV MASSVHDRLA CDPNTKFAAP THSKNWIALI
PKGNCTYRDK IRNAFLQNAS AVVIFNVGSN TNETITMPHA GVEDIVAIMI PEPKGREIVS
LLERNITVTM SITIGTRNLQ KYVSRTSVVF VSISFIVLMI ISLAWLVFYY IQRFRYANAR
DRNQRRLGDA AKKAISKLQV RTIKKGDKET ESDFDNCAVC IEGYKPNDVV RILPCRHLFH
KSCVDPWLLD HRTCPMCKMN ILKALGIPPN ADCMDDLPTD FEGSLGGPPT NQITGASDTT
VNESSVTLDP AVRTVGALQV VQDTDSTPQE GAVIFTTNSE QEPAVSSDSD ISLIMAMEVG
LSDVELSTDQ DCEEVKS
//
