ID H0X3L5_OTOGA Unreviewed; 1242 AA.
AC H0X3L5;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Cordon-bleu WH2 repeat protein {ECO:0000313|Ensembl:ENSOGAP00000009728.2};
GN Name=COBL {ECO:0000313|Ensembl:ENSOGAP00000009728.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000009728.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000009728.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAQR03138719; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03138720; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03138721; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03138722; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03138723; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03138724; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03138725; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0X3L5; -.
DR STRING; 30611.ENSOGAP00000009728; -.
DR Ensembl; ENSOGAT00000010873.2; ENSOGAP00000009728.2; ENSOGAG00000010869.2.
DR eggNOG; ENOG502QTAY; Eukaryota.
DR GeneTree; ENSGT00530000063608; -.
DR HOGENOM; CLU_006259_0_0_1; -.
DR InParanoid; H0X3L5; -.
DR OMA; MISELMM; -.
DR TreeFam; TF333490; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0003785; F:actin monomer binding; IEA:InterPro.
DR CDD; cd21799; WH2_Wa_Cobl; 1.
DR CDD; cd21800; WH2_Wb_Cobl; 1.
DR CDD; cd21801; WH2_Wc_Cobl; 1.
DR InterPro; IPR039895; COBL-like.
DR InterPro; IPR019025; Cordon-bleu_ubiquitin_domain.
DR InterPro; IPR003124; WH2_dom.
DR PANTHER; PTHR47008; PROTEIN CORDON-BLEU; 1.
DR PANTHER; PTHR47008:SF1; PROTEIN CORDON-BLEU; 1.
DR Pfam; PF09469; Cobl; 1.
DR Pfam; PF02205; WH2; 3.
DR SMART; SM00246; WH2; 3.
DR PROSITE; PS51082; WH2; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005225}.
FT DOMAIN 1097..1117
FT /note="WH2"
FT /evidence="ECO:0000259|PROSITE:PS51082"
FT DOMAIN 1137..1157
FT /note="WH2"
FT /evidence="ECO:0000259|PROSITE:PS51082"
FT DOMAIN 1218..1238
FT /note="WH2"
FT /evidence="ECO:0000259|PROSITE:PS51082"
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 257..461
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 501..531
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 544..696
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 768..824
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 882..957
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 980..1078
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1106..1133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1174..1214
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 257..290
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 335..349
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 366..380
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 387..420
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 421..437
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 507..531
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 552..567
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 632..657
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 894..926
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 980..998
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1027..1047
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1048..1062
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1108..1133
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1196..1214
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1242 AA; 133626 MW; FD313AEAAE3DCA52 CRC64;
NKIPRAHIKP CPYMKRMKAR APPPPGKPAA NTDSEQKPPR GVALSPQQNL VHMKEALRDS
TVDVTVVLPS GLEKRSVLNG SHAMMDLLVD LCLQNHLNPS HHALEIRSSE TQQPLSFKPN
TLVGTLNVHT VFLKEKVPEE KVKPGPPKMP EKSVRLVVNY LRTQKAVVRV SPEVPLQNIL
PVICAKCEVT PEHVVLLRDN IAGEELELSK SLSELGIKEL YAWDNRRETF RKSSLGNDET
DKEKKKFLGF FKVNKRSSSK GCLTTPNSPS LHSHSLTLGP SLSLGSISGA SVKSEMKKRR
APPPPGSGLP VQDKASEKVC LGSQVDLQKK KRRAPAPPSP QPPPPSPLVP RRLEDKEEHR
KSTVVSLPLG PSSHSSPDGA PQVPSEAEET VSVSSCFASE DTTEDSGVMS SPSDIVSLDS
QHDSVKSKDK WATDQEDCSD QDLTGTPELG PHKSPSWERN GCEDLHLRTE KAATASKDDE
DLFTGQFHET LAELDGDLEE MEENYETDTS SLTSSTPGIS SLCSQDAMSP KSDIDTIPVT
FIGEVSDDPV DLGSFSNKNN NAGSSDTEDP VGRRAHLVPP QAEPSQRHGT REDTAARCPP
SHDVGRGAHS GSSTTCMDRN SMEMGPKVTV FASDTHKEDL ADTKRRDPWR GCPSREKTQA
VEKANTQSRN EKGDRDKGAV SAPPSWCQRG QNPAGSYGLK YGLTTYKIVP PKSEMRCYDR
GVSLSTGAIE IDELGNLVSP PVSRTIALPS ASLEAETQPI ETVKEFWRRS SVEKPSARGP
PITPTPARTQ QVETEPYADP TPAPTPHLSA HQESGGHLEE GSSWPPMAVA SHSKVPTAHA
TEISFLKPHR RTSSQYVASA IAKRIGLPKA YPNMVGYDHA QKGYVGRTPT PTGQPLGGKG
SMASSLHSET QGRNNSAQQP CTTHPNSHGE EPAVGAHPGG EVSGPRGKLS TQDCPAGVHK
SSNFPLFTSS QRGHVSVGQS CGFSGKQSTV NQETGSACDP KCPLNRTDPH PAHSADARAP
GRVLVNGSTW TPGSSKPPHS PEESGTNSHV ILEKEEKPSL FSIDGHGAES TLSSSIFGPK
KKFRPVVQRP VPKDTSLHTS LMEAIHSAGG KDRLRKTSEH ALEGRPKKPS YVEAESERSA
LLAAIRGHSG ACSLRKVSSF AAEELRSFRN ATLSAQSTEN PQQKEDVPPS PPPASQALST
SRTASRFSTG TLGNPVDARQ ALMDAIRSGT GAARLRKVMV PV
//
