ID H0XDM8_OTOGA Unreviewed; 430 AA.
AC H0XDM8;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Chordin like 2 {ECO:0000313|Ensembl:ENSOGAP00000013981.2};
GN Name=CHRDL2 {ECO:0000313|Ensembl:ENSOGAP00000013981.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000013981.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000013981.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR EMBL; AAQR03001100; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03001101; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03001102; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003780950.1; XM_003780902.1.
DR AlphaFoldDB; H0XDM8; -.
DR STRING; 30611.ENSOGAP00000013981; -.
DR Ensembl; ENSOGAT00000015613.2; ENSOGAP00000013981.2; ENSOGAG00000015608.2.
DR GeneID; 100959475; -.
DR KEGG; oga:100959475; -.
DR CTD; 25884; -.
DR eggNOG; ENOG502QQFQ; Eukaryota.
DR GeneTree; ENSGT00940000161241; -.
DR HOGENOM; CLU_048288_1_0_1; -.
DR InParanoid; H0XDM8; -.
DR OMA; TEPQRCC; -.
DR OrthoDB; 3670395at2759; -.
DR TreeFam; TF106451; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR Gene3D; 6.20.200.20; -; 1.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 2.
DR InterPro; IPR045717; CHRDL1/2.
DR InterPro; IPR045716; CHRDL_1/2_C.
DR InterPro; IPR001007; VWF_dom.
DR PANTHER; PTHR46303:SF3; CHORDIN-LIKE PROTEIN 2; 1.
DR PANTHER; PTHR46303; VWFC DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF19548; CHRDL_1_2_C; 1.
DR Pfam; PF00093; VWC; 3.
DR SMART; SM00214; VWC; 3.
DR SUPFAM; SSF57603; FnI-like domain; 3.
DR PROSITE; PS01208; VWFC_1; 2.
DR PROSITE; PS50184; VWFC_2; 3.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..430
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003545504"
FT DOMAIN 31..96
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 109..175
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 250..315
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT REGION 182..230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 182..203
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 430 AA; 47652 MW; D27765A0F8FE432A CRC64;
MVPEVRVLSF LLGLALLWFP LDSHARARPG MFCLFHGKRY SPGESWHPYL EPQGLMYCLR
CTCAENAHVS CYRLHCPPVH CPQPVTEPQQ CCPRCVEPHT PSGLRAPPKS CQHNGTMYQH
GEIFSAHELF PSRLPNQCVL CSCTEGQIYC GLTNCPEPGC PSPLPLPDSC CQACKDGASE
KSAEEDTTQS RHGVRHSQDL CVGDGGRKRS PGTPAPTGLS TPLGFIPRHF RPKGAGSTTV
KIVLKEKHKK ACVHGGKTYS HGEVWHPAFR SFGPLPCILC TCHDGRQDCQ RVNCPTEYPC
RHPEKVAGKC CKICPEDKAD PGHTEISSTR CPKAPGRVLV HTSVSPSPDN LHRFALEHET
SDQVEIYLWK LVKGIFHLIQ IKKVRKQDFQ KEAQNFQLLA GTHKGHWNVF LAQTPELKVT
ASPDKATKTL
//
