ID H0XEQ7_OTOGA Unreviewed; 459 AA.
AC H0XEQ7;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Ceramide kinase like {ECO:0000313|Ensembl:ENSOGAP00000014445.2};
GN Name=CERKL {ECO:0000313|Ensembl:ENSOGAP00000014445.2};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000014445.2, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000014445.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAQR03082527; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03082528; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0XEQ7; -.
DR STRING; 30611.ENSOGAP00000014445; -.
DR Ensembl; ENSOGAT00000016141.2; ENSOGAP00000014445.2; ENSOGAG00000016136.2.
DR eggNOG; KOG1115; Eukaryota.
DR eggNOG; KOG1116; Eukaryota.
DR GeneTree; ENSGT00940000157578; -.
DR HOGENOM; CLU_013399_2_0_1; -.
DR InParanoid; H0XEQ7; -.
DR OMA; SEDYCDI; -.
DR TreeFam; TF314514; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:Ensembl.
DR GO; GO:0001917; C:photoreceptor inner segment; IEA:Ensembl.
DR GO; GO:0001750; C:photoreceptor outer segment; IEA:Ensembl.
DR GO; GO:0016301; F:kinase activity; IEA:InterPro.
DR GO; GO:0046625; F:sphingolipid binding; IEA:Ensembl.
DR GO; GO:0030148; P:sphingolipid biosynthetic process; IEA:Ensembl.
DR Gene3D; 2.60.200.40; -; 1.
DR InterPro; IPR017438; ATP-NAD_kinase_N.
DR InterPro; IPR045363; CERK_C.
DR InterPro; IPR001206; Diacylglycerol_kinase_cat_dom.
DR InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR PANTHER; PTHR12358:SF26; CERAMIDE KINASE-LIKE PROTEIN; 1.
DR PANTHER; PTHR12358; SPHINGOSINE KINASE; 1.
DR Pfam; PF19280; CERK_C; 1.
DR Pfam; PF00781; DAGK_cat; 1.
DR SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
DR PROSITE; PS50146; DAGK; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005225}.
FT DOMAIN 80..231
FT /note="DAGKc"
FT /evidence="ECO:0000259|PROSITE:PS50146"
FT REGION 390..416
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 390..409
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 459 AA; 51444 MW; 21DEA6C63AA9D113 CRC64;
DMLCKEEMIE LKDIFSVKLK RRCSVKQQGS GTLLGITLFI CLKREQNKLK DSTLDLINLS
EDHCDIWFQQ FRKILAGFPN RPKSLKILLN PQSHKKEAIQ VYYEKVEPLL KLAEIKTDVT
KIVTEYEGHA VSLLKECELQ GFDGVVCVGG DGSASEVAHA LLLRAQKKAG METDGILTPV
RAQLPLGLIP AGSTNVLAHS LHGISHVVTA TLHIIMGHIQ PVDVCTFSTA GKLLRFGFSA
MFGFGGRTLA VAEKYRWMSP NHRRDFAVIK ALAKLKPEDC EISFLPFNSS KDIQERKAQG
SPKCDCDDPW QMIQGQFLNV SIMAIPCLCS VAPRGLAPNT RLNNGSMALI IARDTSRPEF
IKHLKRYASV KNQFSFSFVE TYTVEEVKVH PRSNSSRYNP EREDTPHETA SENSFPWNVD
GDLMEVASEV HVRLHPRLIS LYGESMEEMH DFKVTCNCI
//
