ID H0XNJ0_OTOGA Unreviewed; 1545 AA.
AC H0XNJ0;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE RecName: Full=ABC transporter domain-containing protein {ECO:0000259|PROSITE:PS50893};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000017681.1, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000017681.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAQR03077352; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03077353; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03077354; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03077355; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03077356; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03077357; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03077358; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03077359; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03077360; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03077361; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 30611.ENSOGAP00000017681; -.
DR Ensembl; ENSOGAT00000024814.1; ENSOGAP00000017681.1; ENSOGAG00000027104.1.
DR eggNOG; KOG0059; Eukaryota.
DR GeneTree; ENSGT00940000164007; -.
DR HOGENOM; CLU_000604_19_1_1; -.
DR InParanoid; H0XNJ0; -.
DR OMA; NFGMSIS; -.
DR TreeFam; TF105191; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03263; ABC_subfamily_A; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR PANTHER; PTHR19229:SF139; ATP-BINDING CASSETTE, SUB-FAMILY A (ABC1), MEMBER 14; 1.
DR Pfam; PF12698; ABC2_membrane_3; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 104..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 148..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 193..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 219..238
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 759..782
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 934..954
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 984..1007
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1016..1037
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1043..1066
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1141..1162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 368..604
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1222..1455
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 1545 AA; 176056 MW; 71BC2A571F4716E1 CRC64;
VKYHLRFRNL NALNNSLHPL IGSHNIDWDT SILFPIIPSI GPRNPLEADG GYPGYIREGF
LAVQHSLDKA IMIYHNGRAA ERMFDNVIIL AQRFPYPAHY QDKYLMLFLV IFPWLAVFIF
SLSELPLIRN ITSEKQKKLK DYQLITGLTN FMIWAAYFIA GLLMFIIIVC AICMTLCLKI
VRDRILQYSD PILIVIFFLS FVIASILFGF MISTFFNRAA FAVAAGSFLY FLKFPVTFTS
KNSASLSVKL FSCLSLNTAL TMGIETLVKM EMKRDGVQWN NAFSPVNQDD NITFAHITGM
LLIDAILYGL LAWYVDAVFP GKYGVPKPWY FFLQSVDWFH SRSLLSTQSQ VKSLLLSPCM
DAKKLSLVHY LAVRQHLYYE FTLHNTKIIA ADLSLNLYEG QITVLLGPNG AGKTTTLSIL
TSLLPFTRGK VCINGYDIST NTIQARKIMG FCPQDNLLFK KLTPSEHLYF YSVVKGVPPE
KRSIEIKKVL TDFGLLHVCN VLSMNLSGGT KRKLSLSIAL LGDSKVVILD EPTAGMDPVS
RRATWDILQQ YKESRTILLT TQQMDEADIL GDRIAIMVKG TLRCCGSPVF LKRKYGVGYH
VIMVKKPDCD IENIVQLINQ HIPTASLESN VASELSFILP KEYTQRFEAL FIELEKRQKE
LDIAGFGVSI TTMEEVFLKV SYLSEFKEDK QSLLKSPSLM DQNTGEDKNR DMNVPGGERI
YHHTLNEDSN VMLNTGCTLY IQQFYAMLVK KAIFTRRNWF VVLIQVLGLL GMSYITIGNF
NLDMNIFKRK YNDEPARKMD LEQYGQTIVP VSISGHSDLT QNFTKHLKIM LKAKKQKLQE
VQGDLQKYLV ESQECFYSCI IALSIEVTRN KKKFTFWFNN EAYHSPSLSL AVLDNIIFMS
LSGPDASITV SNKPQPQFTT LVKDKEKKMK GISISFNLLT GISILVSGFC FLTVTERVNN
VKHMQFLRGI YVLNFWLSTL LWDLFIYFIA CCLLLVVFIF IGLHILIEDY HFLDTLFIFL
LFGWSNIPIV YLISFLFSSS TTAFVKIFLI NQFLGILTLL PYSMLLKNGV ILYSTKKSIM
NALLPFPIFN FGVSISKYYN FQEEKISCFS SKNVSNSTRP KSLCLSSVIK LNTYSLEESA
IGQNVIAMAA LGLIFMFLIY LLETTLWRVK TFVLRYIFFG IYKRFYKDKV SLELPEVSKD
EDVQNERGRV LEQRQELLNS PVFIDELTKI YFTFPPIVAI RNISLAIQKE DCFGLLGLNG
AGKTTTFKIL TGVETPTSGD LFMEGLSITK NILKVRSKIG YCPQYDALLH HMTARETMIM
YARLRGISET KINLYVNNFL KMVNLEFHAD KVINTYSTGT KRKLSAAIAL IGNSPIVLLD
EPSTGMDPIA RRLLWNTVIQ ARESGKIIII TSQSMEECDV LCTRLAIMVQ GKFVCLGSPQ
YLKNKFGNIY SLKVKFNTDT IENIIEDFKT FIVHVFPGSV LKHKNQRILN YYIPRKDNGW
GKVFGILEKA KNQFGIEDYS FSQITLEQVF LSFANQDKTA RDYER
//
