ID   H0XPA9_OTOGA            Unreviewed;       406 AA.
AC   H0XPA9;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   RecName: Full=5-azacytidine-induced protein 2 {ECO:0000256|ARBA:ARBA00040858};
GN   Name=AZI2 {ECO:0000313|Ensembl:ENSOGAP00000017950.1};
OS   Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC   Galagidae; Otolemur.
OX   NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000017950.1, ECO:0000313|Proteomes:UP000005225};
RN   [1] {ECO:0000313|Proteomes:UP000005225}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Sequencing Platform;
RA   Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA   Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA   Walker B.J., Sharpe T., Hall G.;
RT   "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL   Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSOGAP00000017950.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR   EMBL; AAQR03005208; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; H0XPA9; -.
DR   STRING; 30611.ENSOGAP00000017950; -.
DR   Ensembl; ENSOGAT00000032572.1; ENSOGAP00000017950.1; ENSOGAG00000005896.2.
DR   eggNOG; ENOG502QV07; Eukaryota.
DR   GeneTree; ENSGT00940000153704; -.
DR   InParanoid; H0XPA9; -.
DR   OMA; PWPSQSC; -.
DR   TreeFam; TF331289; -.
DR   Proteomes; UP000005225; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0097028; P:dendritic cell differentiation; IEA:Ensembl.
DR   GO; GO:0044565; P:dendritic cell proliferation; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0043124; P:negative regulation of canonical NF-kappaB signal transduction; IEA:Ensembl.
DR   GO; GO:0042110; P:T cell activation; IEA:Ensembl.
DR   InterPro; IPR024581; TBD.
DR   PANTHER; PTHR14432:SF6; 5-AZACYTIDINE-INDUCED PROTEIN 2; 1.
DR   PANTHER; PTHR14432; PROSAPIP2 PROTEIN/5-AZACYTIDINE INDUCED GENE 2; 1.
DR   Pfam; PF12845; TBD; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005225}.
FT   DOMAIN          231..279
FT                   /note="Tbk1/Ikki binding"
FT                   /evidence="ECO:0000259|Pfam:PF12845"
FT   REGION          364..391
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          45..72
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          170..197
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        364..378
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   406 AA;  46656 MW;  5AEAEC1D3D92C463 CRC64;
     MDTLVEDDIC ILNHEKANRR DTVTPISVYS GDESVASHFA LVTAYEDIKK RLKDSEKENS
     LLKKRIRFLE EKLIGARLDE ETSSVGREQV NKAYHAYREV CIDRDNLKSK LDKMNKDNSE
     SLKVLNEQLQ SKEVELLQLR TEVETQQVMR NLNPPSANWE VEKLSCDLKI HGLEQELELI
     RKECSDLKIE LQKAKQTDPY QEDNVKSRDL QRLSISRYEH SKHSMLHFSI DNMQHAYWEL
     KREMSNLHLV TQVQAELLRK LKTPTSIKKA CAPGGCFEDL GKDSTRLHLT NFTATYTRHP
     HLSPNGKAVC HTTSSPLPGD VKILSEKAIL QSWTDNERSI PNDGTYFQEH NSYGRNSLED
     NSWVFPSPPK SSETAFGETK SKGLPLPNLP PLHYLDQHNQ NCLYKS
//