ID H0XSA0_OTOGA Unreviewed; 411 AA.
AC H0XSA0;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=IF rod domain-containing protein {ECO:0000259|PROSITE:PS51842};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000018992.1, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000018992.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR EMBL; AAQR03078295; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0XSA0; -.
DR STRING; 30611.ENSOGAP00000018992; -.
DR Ensembl; ENSOGAT00000025867.1; ENSOGAP00000018992.1; ENSOGAG00000032154.1.
DR eggNOG; ENOG502QUS8; Eukaryota.
DR GeneTree; ENSGT00940000153309; -.
DR HOGENOM; CLU_012560_8_1_1; -.
DR InParanoid; H0XSA0; -.
DR OMA; WAQEYET; -.
DR TreeFam; TF332742; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR002957; Keratin_I.
DR PANTHER; PTHR23239; INTERMEDIATE FILAMENT; 1.
DR PANTHER; PTHR23239:SF349; KERATIN, TYPE I CYTOSKELETAL 18; 1.
DR Pfam; PF00038; Filament; 1.
DR PRINTS; PR01248; TYPE1KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225}.
FT DOMAIN 80..372
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT COILED 77..118
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 180..218
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 316..371
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 411 AA; 45995 MW; 6F45B90CE4258CBF CRC64;
MSFTTHSTTF SSNYQSLGSV QTSSYSVTAS SAASVYACAR GWGSWISVSH STSFQGGWGC
GGLATGMAGG LAGIGGIQTE KETMQELNNH LASYLDRVRN LETDNRRLES KIREHVEKKG
LQVRDWAHYF KTIEDLRAQI FANTVDNARH AADDFRVKYE TELAIYQSVE SDIHGFCKVI
DDTDITRLQL ESEMEALKEE LLFMRKNQEE EVKVLQAQIA SGLTVEVDAP KSQNLSKIMA
DMRAQCDELA WKNQEELAKT WSQQIQESTS GVTSQFSEVG AAKTMLTELT RTILGNRTRL
HEKSEVQVEA HYAMQMEQLN GVLLHLESEL AQTRADGQCQ AQEYEALLNI KVKLEAEIAT
YRRLLEDEEN FNRGDALDSG NSVQTIQKTT TCRIVDGKVV SETNNTKVLR H
//
