ID H0Y731_HUMAN Unreviewed; 180 AA.
AC H0Y731;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Potassium channel tetramerization domain containing 17 {ECO:0000313|Ensembl:ENSP00000409638.1};
DE Flags: Fragment;
GN Name=KCTD17 {ECO:0000313|Ensembl:ENSP00000409638.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000409638.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000409638.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=10591208; DOI=10.1038/990031;
RA Dunham I., Hunt A.R., Collins J.E., Bruskiewich R., Beare D.M., Clamp M.,
RA Smink L.J., Ainscough R., Almeida J.P., Babbage A.K., Bagguley C.,
RA Bailey J., Barlow K.F., Bates K.N., Beasley O.P., Bird C.P., Blakey S.E.,
RA Bridgeman A.M., Buck D., Burgess J., Burrill W.D., Burton J., Carder C.,
RA Carter N.P., Chen Y., Clark G., Clegg S.M., Cobley V.E., Cole C.G.,
RA Collier R.E., Connor R., Conroy D., Corby N.R., Coville G.J., Cox A.V.,
RA Davis J., Dawson E., Dhami P.D., Dockree C., Dodsworth S.J., Durbin R.M.,
RA Ellington A.G., Evans K.L., Fey J.M., Fleming K., French L., Garner A.A.,
RA Gilbert J.G.R., Goward M.E., Grafham D.V., Griffiths M.N.D., Hall C.,
RA Hall R.E., Hall-Tamlyn G., Heathcott R.W., Ho S., Holmes S., Hunt S.E.,
RA Jones M.C., Kershaw J., Kimberley A.M., King A., Laird G.K., Langford C.F.,
RA Leversha M.A., Lloyd C., Lloyd D.M., Martyn I.D., Mashreghi-Mohammadi M.,
RA Matthews L.H., Mccann O.T., Mcclay J., Mclaren S., McMurray A.A.,
RA Milne S.A., Mortimore B.J., Odell C.N., Pavitt R., Pearce A.V., Pearson D.,
RA Phillimore B.J.C.T., Phillips S.H., Plumb R.W., Ramsay H., Ramsey Y.,
RA Rogers L., Ross M.T., Scott C.E., Sehra H.K., Skuce C.D., Smalley S.,
RA Smith M.L., Soderlund C., Spragon L., Steward C.A., Sulston J.E.,
RA Swann R.M., Vaudin M., Wall M., Wallis J.M., Whiteley M.N., Willey D.L.,
RA Williams L., Williams S.A., Williamson H., Wilmer T.E., Wilming L.,
RA Wright C.L., Hubbard T., Bentley D.R., Beck S., Rogers J., Shimizu N.,
RA Minoshima S., Kawasaki K., Sasaki T., Asakawa S., Kudoh J., Shintani A.,
RA Shibuya K., Yoshizaki Y., Aoki N., Mitsuyama S., Roe B.A., Chen F., Chu L.,
RA Crabtree J., Deschamps S., Do A., Do T., Dorman A., Fang F., Fu Y., Hu P.,
RA Hua A., Kenton S., Lai H., Lao H.I., Lewis J., Lewis S., Lin S.-P., Loh P.,
RA Malaj E., Nguyen T., Pan H., Phan S., Qi S., Qian Y., Ray L., Ren Q.,
RA Shaull S., Sloan D., Song L., Wang Q., Wang Y., Wang Z., White J.,
RA Willingham D., Wu H., Yao Z., Zhan M., Zhang G., Chissoe S., Murray J.,
RA Miller N., Minx P., Fulton R., Johnson D., Bemis G., Bentley D.,
RA Bradshaw H., Bourne S., Cordes M., Du Z., Fulton L., Goela D., Graves T.,
RA Hawkins J., Hinds K., Kemp K., Latreille P., Layman D., Ozersky P.,
RA Rohlfing T., Scheet P., Walker C., Wamsley A., Wohldmann P., Pepin K.,
RA Nelson J., Korf I., Bedell J.A., Hillier L.W., Mardis E., Waterston R.,
RA Wilson R., Emanuel B.S., Shaikh T., Kurahashi H., Saitta S., Budarf M.L.,
RA McDermid H.E., Johnson A., Wong A.C.C., Morrow B.E., Edelmann L., Kim U.J.,
RA Shizuya H., Simon M.I., Dumanski J.P., Peyrard M., Kedra D., Seroussi E.,
RA Fransson I., Tapia I., Bruder C.E., O'Brien K.P., Wilkinson P.,
RA Bodenteich A., Hartman K., Hu X., Khan A.S., Lane L., Tilahun Y.,
RA Wright H.;
RT "The DNA sequence of human chromosome 22.";
RL Nature 402:489-495(1999).
RN [2] {ECO:0000313|Ensembl:ENSP00000409638.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AL022314; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KF457441; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR IntAct; H0Y731; 1.
DR MassIVE; H0Y731; -.
DR PeptideAtlas; H0Y731; -.
DR ProteomicsDB; 35347; -.
DR Antibodypedia; 11878; 136 antibodies from 20 providers.
DR Ensembl; ENST00000456470.1; ENSP00000409638.1; ENSG00000100379.18.
DR UCSC; uc062dvw.1; human.
DR HGNC; HGNC:25705; KCTD17.
DR VEuPathDB; HostDB:ENSG00000100379; -.
DR GeneTree; ENSGT00940000161746; -.
DR HOGENOM; CLU_070830_1_0_1; -.
DR Proteomes; UP000005640; Chromosome 22.
DR Bgee; ENSG00000100379; Expressed in putamen and 163 other cell types or tissues.
DR ExpressionAtlas; H0Y731; baseline and differential.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR Gene3D; 3.30.70.2000; -; 1.
DR Gene3D; 6.10.140.750; -; 1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR PANTHER; PTHR14958:SF24; BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD17; 1.
DR PANTHER; PTHR14958; POTASSIUM CHANNEL TETRAMERISATION DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF02214; BTB_2; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:H0Y731,
KW ECO:0007829|MaxQB:H0Y731};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT DOMAIN 2..75
FT /note="Potassium channel tetramerisation-type BTB"
FT /evidence="ECO:0000259|Pfam:PF02214"
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSP00000409638.1"
SQ SEQUENCE 180 AA; 20714 MW; 993EBE1AF0F3EFC2 CRC64;
XQTLCREQKS FLSRLCQGEE LQSDRDETGA YLIDRDPTYF GPILNFLRHG KLVLDKDMAE
EGVLEEAEFY NIGPLIRIIK DRMEEKDYTV TQVPPKHVYR VLQCQEEELT QMVSTMSDGW
RFEQLVNIGS SYNYGSEDQA EFLCVVSKEL HSTPNGLSSE SSRKTKVPVR TLSDLRLSLQ
//
