ID H0YWI5_TAEGU Unreviewed; 604 AA.
AC H0YWI5;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Kelch like family member 21 {ECO:0000313|Ensembl:ENSTGUP00000002658.2};
GN Name=KLHL21 {ECO:0000313|Ensembl:ENSTGUP00000002658.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000002658.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000002658.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000002658.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_012425835.1; XM_012570381.1.
DR AlphaFoldDB; H0YWI5; -.
DR STRING; 59729.ENSTGUP00000002658; -.
DR Ensembl; ENSTGUT00000002686.2; ENSTGUP00000002658.2; ENSTGUG00000002586.2.
DR GeneTree; ENSGT00940000158631; -.
DR HOGENOM; CLU_004253_14_6_1; -.
DR InParanoid; H0YWI5; -.
DR OMA; TWSVVGQ; -.
DR OrthoDB; 5472491at2759; -.
DR TreeFam; TF329218; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000007754; Chromosome 21.
DR GO; GO:0031463; C:Cul3-RING ubiquitin ligase complex; IEA:Ensembl.
DR GO; GO:0005827; C:polar microtubule; IEA:Ensembl.
DR GO; GO:0097602; F:cullin family protein binding; IEA:Ensembl.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:Ensembl.
DR GO; GO:0035853; P:chromosome passenger complex localization to spindle midzone; IEA:Ensembl.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR GO; GO:0032465; P:regulation of cytokinesis; IEA:Ensembl.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR24412:SF35; ACTIN-BINDING PROTEIN IPP; 1.
DR PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 2.
DR Pfam; PF13964; Kelch_6; 1.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 5.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000007754};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 43..106
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
SQ SEQUENCE 604 AA; 66575 MW; D517EFFEB70C3BDF CRC64;
MATSTGGTAA GASTAAAAAA GEPAHAVSLL RGLSALRAER SLLDVTVVAG GREFGAHRAV
LAAASGYFRA MFGGALRESR AERVRLHGVE PECLGRLLDF AYTGRVGRLG PDIAERLLRA
ADLLQFPAVK EACGAWLARQ LEPANALDMQ DFAEAFACPE LAAAAHRFVL RHVGELGAQL
ERLPLQRLLS YLRDDGLCIP KEEAAFQLAL RWVRADPATR APLLPQLLAH VRLPFVRRFY
LLAHVESEPL VARCPPCLRL LREARDFQAA RLDRHDRGPC ARMRPRPSTG LAEILVLVGG
CDRDCDELVT VDCYNPRTGH WRYLAEFPEH LGGGYSVAAL GNDIYVTGGS DGSRLYDCVW
RYNSSVNEWT EVSPMLKARE YHSSTVLDGL LYVVASDSTE RYDHTLDSWE ALQPMLYPMD
NCSTTSCRGK LFAIGSLAGK ESMVMQCYDP DSDLWSLVNC GHLPSWSFAP KTVTLNGLMY
FIRDDSAEVD VYNPSKNEWD KIPAMLQVHV GGSVAVLGGK LYVSGGYDNT FELSDVLEAY
DPETRTWSVV GQLPEPIFWH GSVSIFRQFM PETTQEDDSI TLDNTISLSR QNQNLHNQNL
NELP
//
