ID H0Z483_TAEGU Unreviewed; 570 AA.
AC H0Z483;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Ring finger and SPRY domain containing 1 {ECO:0000313|Ensembl:ENSTGUP00000005377.2};
GN Name=RSPRY1 {ECO:0000313|Ensembl:ENSTGUP00000005377.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000005377.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000005377.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000005377.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H0Z483; -.
DR STRING; 59729.ENSTGUP00000005377; -.
DR Ensembl; ENSTGUT00000005431.2; ENSTGUP00000005377.2; ENSTGUG00000005197.2.
DR GeneTree; ENSGT00940000157894; -.
DR HOGENOM; CLU_026400_0_0_1; -.
DR InParanoid; H0Z483; -.
DR OMA; KYSHDSV; -.
DR TreeFam; TF313546; -.
DR Proteomes; UP000007754; Chromosome 11.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR CDD; cd16566; RING-HC_RSPRY1; 1.
DR CDD; cd12883; SPRY_RING; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR045129; RNF123/RSPRY1-like.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR035774; SPRY_RSPRY1.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13363:SF6; RING FINGER AND SPRY DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR13363; RING FINGER AND SRY DOMAIN-CONTAINING; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF13920; zf-C3HC4_3; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000007754};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 294..477
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT DOMAIN 521..556
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 50..98
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..65
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 66..86
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 570 AA; 63959 MW; 2E3A6FD69EA55183 CRC64;
MIVVALVVFY ASRSLFQGLL LTLEHHIPHF LGALGAGSMG NSCVCRDDSG AEDNGNSQGR
QTENSRTHIP EARSHPRDPV RPPRRGRGPH EPRRKKQNVD GLVLDTLAVI RTLVDNDQEP
PYSMITLHEM AETDEGWLEV VQSLIRVIPL EDPLGPAVIT LLLDECPLPT KDALQKLTEI
LNLSGAAACQ DACHPAKHRN TTAVLGCLAE KLAGLLSPGI LEYLLHSLNF QSHPTVMLFA
LIALEKFAQT SENKMTVSES CISDQLILLE KWTDNPDYLK RQVGFCAQWS LDNLFLKEGR
QFTYEKVDLT NIRAMLNSND VSEYLKISPH GLEARCDASS FESVRCTFCV DSGVWYYEVT
VITSGVMQIG WATKDSKFLN HEGYGIGDDE YSCAYDGCRQ LIWYNARSKP HSHPCWKEGD
TIGFLLDLQE KQMIFYLNGN QLPAEKQVFS SAVSGFFAAA SFMSYQQCEF NFGAKPFKYP
PPMKFSTFND HAFLTAEEKI ILPRHRRLAL LKQVSIRENC CTLCCDEVAD TELRPCGHSD
LCMECALQLE TCPLCRQEIQ TRVRQISHIS
//
