ID H0Z6Q1_TAEGU Unreviewed; 1798 AA.
AC H0Z6Q1;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=AT-rich interaction domain 2 {ECO:0000313|Ensembl:ENSTGUP00000006250.2};
GN Name=ARID2 {ECO:0000313|Ensembl:ENSTGUP00000006250.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000006250.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000006250.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000006250.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR STRING; 59729.ENSTGUP00000006250; -.
DR Ensembl; ENSTGUT00000006313.2; ENSTGUP00000006250.2; ENSTGUG00000006070.2.
DR GeneTree; ENSGT00390000016138; -.
DR HOGENOM; CLU_003714_0_0_1; -.
DR InParanoid; H0Z6Q1; -.
DR OMA; NGQKCME; -.
DR TreeFam; TF106406; -.
DR Proteomes; UP000007754; Chromosome 1A.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0016514; C:SWI/SNF complex; IEA:Ensembl.
DR GO; GO:0003677; F:DNA binding; IEA:Ensembl.
DR GO; GO:0060038; P:cardiac muscle cell proliferation; IEA:Ensembl.
DR GO; GO:0060982; P:coronary artery morphogenesis; IEA:Ensembl.
DR GO; GO:0048568; P:embryonic organ development; IEA:Ensembl.
DR GO; GO:0003007; P:heart morphogenesis; IEA:Ensembl.
DR GO; GO:0042592; P:homeostatic process; IEA:Ensembl.
DR GO; GO:0030336; P:negative regulation of cell migration; IEA:Ensembl.
DR GO; GO:0008285; P:negative regulation of cell population proliferation; IEA:Ensembl.
DR GO; GO:0006337; P:nucleosome disassembly; IEA:Ensembl.
DR GO; GO:1905168; P:positive regulation of double-strand break repair via homologous recombination; IEA:Ensembl.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd16866; ARID_ARID2; 1.
DR Gene3D; 1.10.150.60; ARID DNA-binding domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001606; ARID_dom.
DR InterPro; IPR036431; ARID_dom_sf.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR003150; DNA-bd_RFX.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR22970; AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR22970:SF14; AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF01388; ARID; 1.
DR Pfam; PF02257; RFX_DNA_binding; 1.
DR SMART; SM01014; ARID; 1.
DR SMART; SM00501; BRIGHT; 1.
DR SUPFAM; SSF46774; ARID-like; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51011; ARID; 1.
DR PROSITE; PS51526; RFX_DBD; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007754}.
FT DOMAIN 13..105
FT /note="ARID"
FT /evidence="ECO:0000259|PROSITE:PS51011"
FT DOMAIN 495..574
FT /note="RFX-type winged-helix"
FT /evidence="ECO:0000259|PROSITE:PS51526"
FT REGION 784..807
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 855..893
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 928..1019
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1226..1300
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1364..1387
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1405..1427
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1454..1492
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1666..1690
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 866..880
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1232..1247
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1254..1289
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1454..1475
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1670..1690
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1798 AA; 193855 MW; 78574D3E6FE53D83 CRC64;
MANSTGKNHA DQRRKGLAFL DELRQFHHSR GSPFKKIPVV GGKELDLHAL YTRVTTLGGF
GKVSEKNQWG EIVEEFNFPR SCSNAAFALK QYYLRYLEKY EKVHHFGEED DEVQPGNPKP
QLPIGAIPTS YNYQQHSVSD YLRQSYGLSM DLNSPNDYNN KHVMQLEKDP KIITLLLANA
GVFDDTLGSF SAVFGDEWKE KTDRDFVKFW KDIVEDIEVR DLISDRSKSQ DIPSEEWIWE
SLFHPPRKLG INDIEGQRVL QIAVILRNLS FEEGNVKLLA ANRTCLRFLL LSAHSHFISL
RQLGLDTLGN IAAELLLDPV DFKTTHLMFH TVTKCLMSRD RFLKMRGMEI LANLCKAEDN
GVLICEYVDQ ESYKEIICHL TLPDVLLVIS ALEVLYMLTE MGEVACSKIA KVEKSIDTLV
CLVSMDIQMF GPDALTAVKL IEHQCVSQQG ILDVRPQVMD HGSSQAHATG VPASRTAPHV
VPPPGIVEID SEKFACQWLN AHFEVNLDCS VSRAEMYSEY LSTCSKLARG GILTSTGFYK
CLRTVFPNHT VKRVEDPSNN GQAHIHVVGV KRRAIPLPIQ MYYQQPPTSS TPVVRVDSIP
DVSSSPLPAG IPHGLPSVGN HYQRTPINQS STLTATQMSF PIQGVHTVAQ TVSRIPQNPS
IHTQQNAPMT VIQNKGPISC EVVKAAVIQS SVPQSAVPVP IAVGGASNQN HSTPGQQPSV
TVVSSQMLHH QPVIQQQSPL HAVVPGQIPS GTPVTVIQQA VPQGHIFGRV QNLPACSSAV
SQGQQLISTS SQPGQTSSQQ SSAGNQQQDT VIIAPQQYVT TSASNIVSAT TVQNFQVAAG
QVVTIAGVQN PPTSRVGFQN IAPKPLPSQQ GPPAVGQQPQ QQPPAPSQQS VVIVSQPAQQ
GQAYAPAIHQ IVLANPASIP AGQTVQLAGQ PSITPSSSPS PGPVTNNQVP TVMSSSSTTP
QSQGPPPTVS QMLSVKRQQQ QQHSPASSQQ QVQVQQSMQM QVQSQQANTG VGQPNSGESS
LIKQLLLPKR GPSTPGGKLI LPAPQIPPPN NARAPSPQVV YQMANNQTPG FGVQGQSPAQ
QLLVGQQNVQ LVPGAIPPQG AVQTVPISNL QILPGQLISN SPATIFQGTT GNQVTITVVP
NTSFATATVS QGNATQIIAP AGISVSGAQT GVGLQVQTLP ATQAPSAGQS PCTAAPPFKG
DKIICQKEEE AKEATGLHIH ERKIEVMENP SCRRGSANTS NGDAKENEMQ VGSLLNGRKY
SDSSLPPSNS GKIQNEANQC SQVSNGPSLE MGENGAPGKQ NFEQMDTQEI KSDLKKPLVN
GICDFDRGDC SHLSKNIPNH KTSNHVGNGE ISSVEQQGNL DATQQDTAKG DQGERISNGP
VLTLSSSPVV SGTQEAAKLL SQQLSGTNTD LPNGPLASSL NSDVPQQRPS VVVSPQSTAS
VIQGHQIIAV PHSGPRVSQS TLSSEVRSTN GTAECKTAKR PAEDNDRETV PGIPNKVGVR
IVTISDPNNA GCSATMVAVP AGADPSTVAK VAIESAVQQK QQHPTTYIQS MVTQSTPATS
IPTVQVQGQQ MNLQPPSYTA ASQHAEQMKK PGQNFMCLWQ SCKKWFQTPS QVFYHAATEH
GGKDVYPGQC LWEGCEPFQR QRFSFITHLQ DKHCSRDALL AGLKQDEHGQ AGNQKPSNKQ
PAAGATASTP RAQKAIVNHP SAALMALRRG SRNLVFRDFT DEKEGPITKH IRLTAALILK
NIGKYSECGR RLLKRHENHL SVLAISNMEA SSTLAKCLYE LNFTVQSKEH EKDSEMLQ
//
