ID H0ZDV6_TAEGU Unreviewed; 1099 AA.
AC H0ZDV6;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 68.
DE RecName: Full=Myosin XVB {ECO:0008006|Google:ProtNLM};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000008768.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000008768.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000008768.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR AlphaFoldDB; H0ZDV6; -.
DR STRING; 59729.ENSTGUP00000008768; -.
DR Ensembl; ENSTGUT00000008861.2; ENSTGUP00000008768.2; ENSTGUG00000008499.2.
DR GeneTree; ENSGT00940000155335; -.
DR InParanoid; H0ZDV6; -.
DR OMA; RHIFAIA; -.
DR TreeFam; TF351254; -.
DR Proteomes; UP000007754; Chromosome 18.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.190; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 6.20.240.20; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR Gene3D; 1.25.40.530; MyTH4 domain; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR000857; MyTH4_dom.
DR InterPro; IPR038185; MyTH4_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR22692; MYOSIN VII, XV; 1.
DR PANTHER; PTHR22692:SF16; MYOSIN XVB; 1.
DR Pfam; PF00612; IQ; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF00784; MyTH4; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00015; IQ; 2.
DR SMART; SM00242; MYSc; 1.
DR SMART; SM00139; MyTH4; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50096; IQ; 2.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51016; MYTH4; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000007754}.
FT DOMAIN 1..676
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 841..992
FT /note="MyTH4"
FT /evidence="ECO:0000259|PROSITE:PS51016"
FT REGION 555..577
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT BINDING 92..99
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1099 AA; 125068 MW; EA69BB1C95188153 CRC64;
MSPFLCFREV SESSVLLCLK KRFHCNLIYT YIGQILISVN PFKDLRIYSE DVATMYQQGT
LSKNAPHIFA IAEMAYTLSQ SSGQEQCVLI SGHSGSGKTE AAKAIVQYLT TLYQGSDSHR
IRQPCSVLPI LESFGNARTI LNDNSSRFGK LLDIHLRHGI VVGTSISQYL LEKSRVVFQA
HGERNYHVFY ELLAGLPVEQ KEEMYLQEAE SYFYLNQGRA CEVLGKEDSQ DFLVLVQALE
GISLSDDQLN STWAVLAAIL QLGNICFTSY EKESFEHAAI ASDTEIQIVA NLLRVSAELL
QSAVTHRVTV TSYDRIFTPL SVEGAIDARD SIAKALYYLL FEWLLLRINE WLAPWESDCA
VGIVDIHGFE DLGVNSLEQL CINFANEHLQ WFFCQTVIAQ EEEEYSQEQL AWIPISKMCS
ELCLDFLTAK PHGILCILDD QTSLIQATDH TFLQKCHYHH GNSPWYTKPK LPLPEFTVQH
YAGPVTYQVH KFLNKNRDQL RPEVLDIFSQ SRLKVVSHIF QRAKAAYSQR RELGGRGRGL
RPQASTLVSK FQQSLQDLTA KLRGSHAFFI RCITPNPRKL SNVFDVEYVN CQLRHSGILE
AIHILKEGFP VHLPFQSFLA RYGLLAGSRP SSLQQREGCA AVLAHVLGNP SDLYQIGVTK
VFLKEKGRQL LERRWLQRQS WAVVTLQRKF RRLLQRRRLQ EKVTLIQAHF RGYQARKRYR
RLKKTLVQFK SMIIISRPLI QRRKRCQVTT EQGERPQMLW RQKSLLWLRC SIPDVGLLEI
PAELADLLHF IEGEKSSSFP PFPTQPPEVK VKDDLSLPPT INSYPFSSFI KSHFQKPDFP
APGQPLQHPL THLDAEHQES ALEINKLILR FIGDQSLRGW QEVLLGNYIA GRGLGDAALR
NEIFSQVVAQ TWRNPDTEHS QRGWVLMATL LSCFGPSPAL EKPLLKFVSD YGMEGYSAVC
QRKMLTAAQC TETEPAPSRA YPPTQLEWTA NQRRGKMVLD VHTFNGNSFS AEVESWMTGE
QYAAWILSAR GCDKKTRGWS VSMFTGNTWQ DLLGCDFVLD LIGEMEETSN FISSSQAPTE
YPITPERDRS ILHSSDLDM
//
