ID H0ZSR3_TAEGU Unreviewed; 442 AA.
AC H0ZSR3;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Transcription factor AP-2 beta {ECO:0000313|Ensembl:ENSTGUP00000013659.2};
GN Name=TFAP2B {ECO:0000313|Ensembl:ENSTGUP00000013659.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000013659.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000013659.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000013659.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the AP-2 family.
CC {ECO:0000256|ARBA:ARBA00007770}.
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DR AlphaFoldDB; H0ZSR3; -.
DR STRING; 59729.ENSTGUP00000027782; -.
DR Ensembl; ENSTGUT00000013815.2; ENSTGUP00000013659.2; ENSTGUG00000022691.1.
DR GeneTree; ENSGT00950000182848; -.
DR HOGENOM; CLU_035175_4_1_1; -.
DR TreeFam; TF313718; -.
DR Proteomes; UP000007754; Chromosome 3.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR InterPro; IPR004979; TF_AP2.
DR InterPro; IPR008122; TF_AP2_beta.
DR InterPro; IPR013854; TF_AP2_C.
DR PANTHER; PTHR10812; TRANSCRIPTION FACTOR AP-2; 1.
DR PANTHER; PTHR10812:SF14; TRANSCRIPTION FACTOR AP-2-BETA; 1.
DR Pfam; PF03299; TF_AP-2; 1.
DR PRINTS; PR01750; AP2BTNSCPFCT.
DR PRINTS; PR01748; AP2TNSCPFCT.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000007754}.
FT DOMAIN 212..406
FT /note="Transcription factor AP-2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03299"
FT REGION 1..121
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..42
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 43..61
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 62..101
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 442 AA; 48344 MW; 9557A686313DDFAE CRC64;
MLVHTYSAMD RHDGVPSHSS RLSQLGSVSQ GPYSSAPPLS HTPSSDFQPP YFPPPYQPLP
YHQSQDPYSH VNDPYSLNPL HQPQQHPWGQ RQRQEVGSET GSLLPQPRAA LPQLSGLDPR
RDYHSVRRPD VLLHSAHHGL DSGMGDSLSL HGIGHPGMEE VQSVEDANNS GMNLLDQSVI
KKVPVPPKSV TSLMMNKDGF LGGISVNTGE VFCSVPGRLS LLSSTSKYKV TVGEVQRRLS
PPECLNASLL GGVLRRAKSK NGGRSLRERL EKIGLNLPAG RRKAANVTLL TSLVEGEAVH
LARDFGYICE TEFPAKAVSE YLNRQHTDPS DLHSRKNMLL ATKQLCKEFT DLLAQDRTPI
GNSRPTPILE PGIQSCLTHF SLITHGFGAP AICAALTALQ NYLTEALKGM DKMFLNNNTA
NRHTSGEGPA LPAWLMSFFK ED
//
