ID H1B4F7_9FIRM Unreviewed; 472 AA.
AC H1B4F7;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Iron-only hydrogenase maturation rSAM protein HydG {ECO:0000313|EMBL:EHO32615.1};
GN ORFNames=HMPREF0981_00090 {ECO:0000313|EMBL:EHO32615.1};
OS Erysipelotrichaceae bacterium 6_1_45.
OC Bacteria; Bacillota; Erysipelotrichia; Erysipelotrichales;
OC Erysipelotrichaceae.
OX NCBI_TaxID=469614 {ECO:0000313|EMBL:EHO32615.1, ECO:0000313|Proteomes:UP000003818};
RN [1] {ECO:0000313|EMBL:EHO32615.1, ECO:0000313|Proteomes:UP000003818}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=6_1_45 {ECO:0000313|EMBL:EHO32615.1,
RC ECO:0000313|Proteomes:UP000003818};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Strauss J.,
RA Allen-Vercoe E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Brown A.,
RA Chapman S.B., Chen Z., Dunbar C., Freedman E., Gearin G., Goldberg J.,
RA Griggs A., Gujja S., Heiman D., Howarth C., Larson L., Lui A.,
RA MacDonald P.J.P., Montmayeur A., Murphy C., Neiman D., Pearson M.,
RA Priest M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C.,
RA Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Erysipelotrichaceae bacterium 6_1_45.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHO32615.1}.
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DR EMBL; ACTK01000002; EHO32615.1; -; Genomic_DNA.
DR AlphaFoldDB; H1B4F7; -.
DR PATRIC; fig|469614.3.peg.88; -.
DR HOGENOM; CLU_046249_0_0_9; -.
DR BioCyc; EBAC469614-HMP:GMFG-90-MONOMER; -.
DR Proteomes; UP000003818; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0044271; P:cellular nitrogen compound biosynthetic process; IEA:UniProt.
DR GO; GO:0018130; P:heterocycle biosynthetic process; IEA:UniProt.
DR GO; GO:1901362; P:organic cyclic compound biosynthetic process; IEA:UniProt.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR GO; GO:0044272; P:sulfur compound biosynthetic process; IEA:UniProt.
DR GO; GO:0042364; P:water-soluble vitamin biosynthetic process; IEA:UniProt.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR010722; BATS_dom.
DR InterPro; IPR024007; FeFe-hyd_mat_HydG.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR034428; ThiH/NoCL/HydG-like.
DR NCBIfam; TIGR03955; rSAM_HydG; 1.
DR PANTHER; PTHR43583; 2-IMINOACETATE SYNTHASE; 1.
DR PANTHER; PTHR43583:SF2; BIOTIN AND THIAMIN SYNTHESIS ASSOCIATED DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF06968; BATS; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDF00319; Fe_hydrogenase_maturase_(HydG; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00876; BATS; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 82..312
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 472 AA; 53704 MW; B8DF67F1AE9C9EB2 CRC64;
MYNKHSLKAS EFIDDEEIKE TLRFAQENKR NKELISSLIE RAKDCKGLTH REAAVLLECE
LPEENEKMFT LAKQIKQKLY GNRIVMFAPL YLSNYCVNGC VYCPYHHKNK HIRRKKLTQE
EIRQEVIALQ DMGHKRLALE TGEDPVHSPI DYVLESIKTI YGIKHKNGAI RRVNVNIAAT
TVENYKKLKD AGIGTYILFQ ETYHKESYEQ LHPNGPKSNY AYHTEAMDRA MEGGIDDVGC
GVLFGLNMYR YDFVGLLMHA EHLEAVHGVG PHTISVPRIC PADDINPDEF TNVISDEIFT
KIVAVLRIAV PYTGMIISTR ESQKTREKVL DLGISQISGA SSTSVGGYAV PEKEEENSAQ
FDVSDNRTLD EVVNWLLKLG YIPSFCTACY REGRTGDRFM SLVKSGQIAN CCHPNALLTL
REYLDDYAKE DTKKLGSARI EQELLNIPNE KARETCTSYL HSIDEGKRDF RF
//
