ID H1PXM5_9FUSO Unreviewed; 375 AA.
AC H1PXM5;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 24-JAN-2024, entry version 58.
DE RecName: Full=DNA replication and repair protein RecF {ECO:0000256|HAMAP-Rule:MF_00365};
GN Name=recF {ECO:0000256|HAMAP-Rule:MF_00365};
GN ORFNames=HMPREF0402_03168 {ECO:0000313|EMBL:EHO78063.1};
OS Fusobacterium ulcerans 12-1B.
OC Bacteria; Fusobacteriota; Fusobacteriia; Fusobacteriales; Fusobacteriaceae;
OC Fusobacterium.
OX NCBI_TaxID=457404 {ECO:0000313|EMBL:EHO78063.1, ECO:0000313|Proteomes:UP000003233};
RN [1] {ECO:0000313|EMBL:EHO78063.1, ECO:0000313|Proteomes:UP000003233}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=12_1B {ECO:0000313|EMBL:EHO78063.1,
RC ECO:0000313|Proteomes:UP000003233};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Strauss J., Ambrose C.E.,
RA Allen-Vercoe E., Walker B., Young S.K., Zeng Q., Gargeya S., Fitzgerald M.,
RA Haas B., Abouelleil A., Alvarado L., Arachchi H.M., Berlin A.M.,
RA Chapman S.B., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Larimer J., McCowen C., Montmayeur A., Murphy C., Neiman D.,
RA Pearson M., Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Fusobacterium ulcerans 12_1B.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: The RecF protein is involved in DNA metabolism; it is
CC required for DNA replication and normal SOS inducibility. RecF binds
CC preferentially to single-stranded, linear DNA. It also seems to bind
CC ATP. {ECO:0000256|HAMAP-Rule:MF_00365}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00365}.
CC -!- SIMILARITY: Belongs to the RecF family. {ECO:0000256|HAMAP-
CC Rule:MF_00365}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHO78063.1}.
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DR EMBL; AGWJ02000027; EHO78063.1; -; Genomic_DNA.
DR RefSeq; WP_005978551.1; NZ_KE161010.1.
DR AlphaFoldDB; H1PXM5; -.
DR GeneID; 78454390; -.
DR PATRIC; fig|457404.5.peg.2945; -.
DR HOGENOM; CLU_040267_0_1_0; -.
DR Proteomes; UP000003233; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003697; F:single-stranded DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.20.1050.90; RecF/RecN/SMC, N-terminal domain; 1.
DR HAMAP; MF_00365; RecF; 1.
DR InterPro; IPR001238; DNA-binding_RecF.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR InterPro; IPR042174; RecF_2.
DR NCBIfam; TIGR00611; recf; 1.
DR PANTHER; PTHR32182; DNA REPLICATION AND REPAIR PROTEIN RECF; 1.
DR PANTHER; PTHR32182:SF0; DNA REPLICATION AND REPAIR PROTEIN RECF; 1.
DR Pfam; PF02463; SMC_N; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP-
KW Rule:MF_00365};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_00365};
KW DNA damage {ECO:0000256|HAMAP-Rule:MF_00365};
KW DNA repair {ECO:0000256|HAMAP-Rule:MF_00365};
KW DNA replication {ECO:0000256|HAMAP-Rule:MF_00365};
KW DNA-binding {ECO:0000256|HAMAP-Rule:MF_00365};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP-
KW Rule:MF_00365}; SOS response {ECO:0000256|HAMAP-Rule:MF_00365}.
FT DOMAIN 5..341
FT /note="RecF/RecN/SMC N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02463"
FT BINDING 30..37
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00365"
SQ SEQUENCE 375 AA; 44160 MW; C1563A8504C95223 CRC64;
MEILEINYVN FRNLQDGNVK FFPKLNLFYG KNGQGKTSLL EALYFNSTGK SFRTNKSSEM
MKYGYKRTGV YVVYKDNIGE KTLTVKFNNE DKKEYSYNGK KVQYDEFYGK LNVVTYIPED
IVLITGSPSV RRNFFDGEIA QTSSEYFQEL KNFNKILKIR NKYLKEKKHK EPEFAIYQDE
FVKYGAKVIE KRMEYVKKIS IILNLNYRKL FDDKKELSLQ YQCHLGNVKK MTLKEIEDAL
RKRIEEKLGQ ELRYGFSLSG PQKDDFLFFL NSYEAKSTAS QGEKKSIIFS LKLSEIDMVL
REKKESPILI IDDISSYFDS NRKDSILNYL EKRNIQVFIS STGGLGIDTK DFYVEKGEIS
YDRDREYREN DRKGN
//
