ID   H1S3Z7_9BURK            Unreviewed;       519 AA.
AC   H1S3Z7;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   24-JAN-2024, entry version 30.
DE   SubName: Full=AMP-dependent synthetase and ligase {ECO:0000313|EMBL:EHP42744.1};
GN   ORFNames=OR16_12955 {ECO:0000313|EMBL:EHP42744.1};
OS   Cupriavidus basilensis OR16.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Cupriavidus.
OX   NCBI_TaxID=1127483 {ECO:0000313|EMBL:EHP42744.1, ECO:0000313|Proteomes:UP000005808};
RN   [1] {ECO:0000313|EMBL:EHP42744.1, ECO:0000313|Proteomes:UP000005808}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OR16 {ECO:0000313|EMBL:EHP42744.1,
RC   ECO:0000313|Proteomes:UP000005808};
RX   PubMed=22461549; DOI=10.1128/JB.06752-11;
RA   Cserhati M., Kriszt B., Szoboszlay S., Toth A., Szabo I., Tancsics A.,
RA   Nagy I., Horvath B., Nagy I., Kukolya J.;
RT   "De Novo Genome Project of Cupriavidus basilensis OR16.";
RL   J. Bacteriol. 194:2109-2110(2012).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EHP42744.1}.
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DR   EMBL; AHJE01000029; EHP42744.1; -; Genomic_DNA.
DR   RefSeq; WP_006158219.1; NZ_AHJE01000029.1.
DR   AlphaFoldDB; H1S3Z7; -.
DR   PATRIC; fig|1127483.3.peg.2600; -.
DR   OrthoDB; 9766486at2; -.
DR   Proteomes; UP000005808; Unassembled WGS sequence.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   CDD; cd17631; FACL_FadD13-like; 1.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR   PANTHER; PTHR43767:SF1; NONRIBOSOMAL PEPTIDE SYNTHASE PES1 (EUROFUNG)-RELATED; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   Ligase {ECO:0000313|EMBL:EHP42744.1}.
FT   DOMAIN          8..375
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          425..500
FT                   /note="AMP-binding enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13193"
SQ   SEQUENCE   519 AA;  56075 MW;  D7F32F6C6272A97F CRC64;
     MYLTQALHRA VQQHPERIAV RYGERQRSFR QLAERVARLA GGLRKLGMQS GDRVAMLSLN
     SDRFLEYQMA VPWAGGVLNP CNTRWSAAEI LYSLDDSGST ILLVDETFRA LAVQLRRDAA
     TLRELIYCGD GEVPSGMHGY EALLANAAPV PDAVRRDEDL AGIFYTGGTT GFPKGVMLSH
     ANLCASGLAL RAEGLATPGG TYLHAAPMFH LADMGLAMPQ WMEGNTHAII PAFNPELVLD
     TLERDRVTHM LLVPTMIQMM VDHPAMKKPR DLSALQAIIY GASPISEAVL ERAMAALPGV
     GFVQAYGMTE LSPLATINPA WYHTAEGRAQ GKLRAAGRAS YTSEVRIVDG EGCEVPRGTV
     GEVAVRGPTV MQGYWNKPAE NAAAVRDGWM HTGDGGYMDE DGFIFIVDRL KDMIVSGGEN
     VYSAEVENAL AQHPAVVASA VIGVPSAEWG EAVHAVVVGR PGTSATAGEL IDHCKTLIAG
     YKCPRSVEFR DALPLSGAGK ILKIELRKPF WEGQQRQVS
//