ID   H1SCQ3_9BURK            Unreviewed;       517 AA.
AC   H1SCQ3;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   24-JAN-2024, entry version 30.
DE   SubName: Full=Amp-dependent synthetase and ligase {ECO:0000313|EMBL:EHP39708.1};
GN   ORFNames=OR16_30029 {ECO:0000313|EMBL:EHP39708.1};
OS   Cupriavidus basilensis OR16.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Cupriavidus.
OX   NCBI_TaxID=1127483 {ECO:0000313|EMBL:EHP39708.1, ECO:0000313|Proteomes:UP000005808};
RN   [1] {ECO:0000313|EMBL:EHP39708.1, ECO:0000313|Proteomes:UP000005808}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OR16 {ECO:0000313|EMBL:EHP39708.1,
RC   ECO:0000313|Proteomes:UP000005808};
RX   PubMed=22461549; DOI=10.1128/JB.06752-11;
RA   Cserhati M., Kriszt B., Szoboszlay S., Toth A., Szabo I., Tancsics A.,
RA   Nagy I., Horvath B., Nagy I., Kukolya J.;
RT   "De Novo Genome Project of Cupriavidus basilensis OR16.";
RL   J. Bacteriol. 194:2109-2110(2012).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EHP39708.1}.
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DR   EMBL; AHJE01000084; EHP39708.1; -; Genomic_DNA.
DR   RefSeq; WP_006161650.1; NZ_AHJE01000084.1.
DR   AlphaFoldDB; H1SCQ3; -.
DR   PATRIC; fig|1127483.3.peg.6001; -.
DR   OrthoDB; 9766486at2; -.
DR   Proteomes; UP000005808; Unassembled WGS sequence.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR   PANTHER; PTHR43767:SF1; NONRIBOSOMAL PEPTIDE SYNTHASE PES1 (EUROFUNG)-RELATED; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   Ligase {ECO:0000313|EMBL:EHP39708.1}.
FT   DOMAIN          16..373
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          429..503
FT                   /note="AMP-binding enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13193"
SQ   SEQUENCE   517 AA;  55796 MW;  4FF07F012DFDC93B CRC64;
     MSPTSTDFTP LAALVDAQAE LRPHHPAVVL DERSVDFASL NRLADRVAAA LQRDGVPAQG
     AVAICAATSI EYVCAFLGCL RAGVAVAPLS PSLNPETLRG MVQDSGARRL LIDASTRQAL
     HGLEAELGIP CIALDDSHAG IAFSHWLAPE HARPAPVDVQ PDWAFNLIYS SGTTGVPKGI
     IQPFGMRASH VQRATQGGYG PDSVALLSTP LYSNTTLVSL FPTLSLGGTV VLMRKFDAGQ
     YLALAARHHV THTMLVPVQY QRILAHPDFA STDLSSFRYK FCTSAPFAAA LKAQVLQRWP
     GALVEYYGMT EGGGRCELRA HEHPDKLHTV GRPSPDTDMR LLDDQGRELP ADAPRDTPGE
     IVGHSPAMMS GYHNHPEKTA EAEWFDATGK RFIRTGDVGY FDADGFLILM DRKKDMVISG
     GFNIYPSDIE TVLLGHPAIA DAAVVGVPSE RWGETPVAFV VLRPGATAQA AALLDWANDR
     LEKMQRLAAL ELSPELPRNA IGKVLKRDLR DQYGRAP
//