ID H1VGF9_COLHI Unreviewed; 1009 AA.
AC H1VGF9;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=alpha-glucosidase {ECO:0000256|ARBA:ARBA00012741};
DE EC=3.2.1.20 {ECO:0000256|ARBA:ARBA00012741};
GN ORFNames=CH063_10175 {ECO:0000313|EMBL:CCF39312.1};
OS Colletotrichum higginsianum (strain IMI 349063) (Crucifer anthracnose
OS fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC Colletotrichum destructivum species complex.
OX NCBI_TaxID=759273 {ECO:0000313|EMBL:CCF39312.1, ECO:0000313|Proteomes:UP000007174};
RN [1] {ECO:0000313|Proteomes:UP000007174}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IMI 349063 {ECO:0000313|Proteomes:UP000007174};
RX PubMed=22885923; DOI=10.1038/ng.2372;
RA O'Connell R.J., Thon M.R., Hacquard S., Amyotte S.G., Kleemann J.,
RA Torres M.F., Damm U., Buiate E.A., Epstein L., Alkan N., Altmueller J.,
RA Alvarado-Balderrama L., Bauser C.A., Becker C., Birren B.W., Chen Z.,
RA Choi J., Crouch J.A., Duvick J.P., Farman M.A., Gan P., Heiman D.,
RA Henrissat B., Howard R.J., Kabbage M., Koch C., Kracher B., Kubo Y.,
RA Law A.D., Lebrun M.-H., Lee Y.-H., Miyara I., Moore N., Neumann U.,
RA Nordstroem K., Panaccione D.G., Panstruga R., Place M., Proctor R.H.,
RA Prusky D., Rech G., Reinhardt R., Rollins J.A., Rounsley S., Schardl C.L.,
RA Schwartz D.C., Shenoy N., Shirasu K., Sikhakolli U.R., Stueber K.,
RA Sukno S.A., Sweigard J.A., Takano Y., Takahara H., Trail F.,
RA van der Does H.C., Voll L.M., Will I., Young S., Zeng Q., Zhang J.,
RA Zhou S., Dickman M.B., Schulze-Lefert P., Ver Loren van Themaat E.,
RA Ma L.-J., Vaillancourt L.J.;
RT "Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered
RT by genome and transcriptome analyses.";
RL Nat. Genet. 44:1060-1065(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing (1->4)-linked alpha-D-
CC glucose residues with release of alpha-D-glucose.; EC=3.2.1.20;
CC Evidence={ECO:0000256|ARBA:ARBA00001657};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 31 family.
CC {ECO:0000256|ARBA:ARBA00007806, ECO:0000256|RuleBase:RU361185}.
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DR EMBL; CACQ02003427; CCF39312.1; -; Genomic_DNA.
DR AlphaFoldDB; H1VGF9; -.
DR STRING; 759273.H1VGF9; -.
DR EnsemblFungi; CCF39312; CCF39312; CH063_10175.
DR VEuPathDB; FungiDB:CH63R_06054; -.
DR eggNOG; KOG1065; Eukaryota.
DR HOGENOM; CLU_000631_11_0_1; -.
DR Proteomes; UP000007174; Unassembled WGS sequence.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0032450; F:maltose alpha-glucosidase activity; IEA:UniProtKB-EC.
DR CDD; cd06602; GH31_MGAM_SI_GAA; 1.
DR CDD; cd14752; GH31_N; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 2.
DR Gene3D; 2.60.40.1760; glycosyl hydrolase (family 31); 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 2.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR030458; Glyco_hydro_31_AS.
DR InterPro; IPR048395; Glyco_hydro_31_C.
DR InterPro; IPR030459; Glyco_hydro_31_CS.
DR InterPro; IPR000322; Glyco_hydro_31_TIM.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR22762; ALPHA-GLUCOSIDASE; 1.
DR PANTHER; PTHR22762:SF133; ALPHA-GLUCOSIDASE; 1.
DR Pfam; PF01055; Glyco_hydro_31_2nd; 1.
DR Pfam; PF21365; Glyco_hydro_31_3rd; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
DR PROSITE; PS00129; GLYCOSYL_HYDROL_F31_1; 1.
DR PROSITE; PS00707; GLYCOSYL_HYDROL_F31_2; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Glycosidase {ECO:0000256|RuleBase:RU361185};
KW Hydrolase {ECO:0000256|RuleBase:RU361185, ECO:0000313|EMBL:CCF39312.1};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..1009
FT /note="alpha-glucosidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003555986"
FT DOMAIN 341..777
FT /note="Glycoside hydrolase family 31 TIM barrel"
FT /evidence="ECO:0000259|Pfam:PF01055"
FT DOMAIN 785..878
FT /note="Glycosyl hydrolase family 31 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21365"
SQ SEQUENCE 1009 AA; 110096 MW; AED6075C1974BF68 CRC64;
MFARAPLLLP AAAVMALCTM ARVADLGRPS APQYLASTSI ASSTSQFTVP ASANEGALLI
PNIEDPESTD PQSVCPGYTA SHIQTTSYGF TADLDLAGSA CNVYGNDVEA LSLVVEYLAT
DRLHVQVLPR YIGTRNSTWF ILPGELIPKP AADGKASSDG SNSDLEFKWA NEPTFGFNVS
RKSTGDVLFT TAGTKLVFED QFFEFASPLP KNYNLYGLGE VIHGFKLNNN LTRTLYAADV
GDPIDGNIYG SHPVYLDTRY YQVNSDTKEA VYVANATDKN AEYTSYTHGV FLRNSHAQEV
LLRESNITWR GLGGTIDLYF YAGPTADAVM KSYQKTTVGL PAMQQYWTFG FHQCRWGYTS
WDNLQEVTDD FAKFKIPLET IWADIDYMNQ YRDFENDANS WSYEDAARVL GSLHKNGQHF
VPIVDSAIYS PNSENASDAY PTYDRGADAD AFMLNPDGSL YIGAVWPGYT VFPDWIGAVL
NGSRTFEWWK TELVTWFDKV AFDGIWIDMS EVSSFCVGSC GSDNLTLNPA HPPFLLPGEP
GNEVLEYPEG FDRTNGTEAA SVSSLSSSLA AARTATAAIP SSSLYTTTSY LRTTPTPGVR
NVNYPPYVIN NIQGDLAVHA VSPNATHHGG TQEYDFHNLF GHQILNATYQ ALLSVLPGKR
PFIIGRSTFA GSGKWAGHWG GDNASLWAYM FFSIPQALAF SIFGVPMFGV DTCGFSGNTD
MELCARWMQL SAFFPFYRNH NVIGAIPQEP YRWAAVADAS RAAMAIRYAL LPYVYTAFYR
AHKQGDTVMK ALAWEFADEP WLAGADRQFL LGPAVMVTPC LEQGASTVDG VFPGVGQGTV
WYDWYNQSAI TGVSTGQNVT IDAPLGHIPV YVRGGYVIPT QEPGLTTAES RSNPWGLLVA
LDDKGTAKGS LYVDDGESVE QEATLTVELS ASENSLKATP SGEFRDSNSL GTVTVMGVQG
DVSAVTLDGR DLDSASWTFN STTRALHIHG LKSRTSEGAW SSARELVWS
//
