ID H1Y0E2_9SPHI Unreviewed; 380 AA.
AC H1Y0E2;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Efflux transporter, RND family, MFP subunit {ECO:0000313|EMBL:EHQ28191.1};
GN ORFNames=Mucpa_4100 {ECO:0000313|EMBL:EHQ28191.1};
OS Mucilaginibacter paludis DSM 18603.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Mucilaginibacter.
OX NCBI_TaxID=714943 {ECO:0000313|EMBL:EHQ28191.1, ECO:0000313|Proteomes:UP000002774};
RN [1] {ECO:0000313|EMBL:EHQ28191.1, ECO:0000313|Proteomes:UP000002774}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 18603 {ECO:0000313|EMBL:EHQ28191.1,
RC ECO:0000313|Proteomes:UP000002774};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Han J., Lapidus A., Bruce D., Goodwin L., Pitluck S., Peters L.,
RA Kyrpides N., Mavromatis K., Ivanova N., Mikhailova N., Held B.,
RA Detter J.C., Tapia R., Han C., Land M., Hauser L., Markowitz V.,
RA Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Tindall B., Brambilla E.,
RA Klenk H.-P., Eisen J.A.;
RT "The permanent draft genome of Mucilaginibacter paludis DSM 18603.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; CM001403; EHQ28191.1; -; Genomic_DNA.
DR RefSeq; WP_008508939.1; NZ_CM001403.1.
DR AlphaFoldDB; H1Y0E2; -.
DR STRING; 714943.Mucpa_4100; -.
DR eggNOG; COG0845; Bacteria.
DR HOGENOM; CLU_018816_2_1_10; -.
DR OrthoDB; 9801814at2; -.
DR Proteomes; UP000002774; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30158; ACRA/E-RELATED COMPONENT OF DRUG EFFLUX TRANSPORTER; 1.
DR PANTHER; PTHR30158:SF23; MULTIDRUG RESISTANCE PROTEIN MEXA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000002774};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..380
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003556944"
FT DOMAIN 58..282
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT COILED 134..161
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 380 AA; 41128 MW; 310BDE9816863532 CRC64;
MKTIFLAVIA LSLYSCSTKP QTQTAPPPPS LPVATVLAGN DTTYQEYPAS IEGAINVEIR
PQVSGSLDKV FVDEGAYVNA GEALFKINDQ PYRAQLNNAL AGQHAAESAL INSQLEIQKL
TPLVQNKVVS EYQLKTARAA YQIAKANIEQ AKANVATAQI NVGYTTIKAP VSGYIGRLVK
KQGSLVTPAD IEALTLLSDV HTVHVYFSLA EKDFVSFKEQ YPGETLTDKL KHLPAVGLLL
ADNSQYAKQG KIDMIDGQFD KNTGAITLRA TFPNTQGLLR SGNTGKIRLS LNHRDALIVP
ESATIEMQDK IFVFTVGDSS KVKKQPIYIV GKTHGHYLVK DNEGIKAGDQ IVLEGIDKLQ
EGMVIQPQKA ADKVAAVVKK
//
