ID H1YYS2_9EURY Unreviewed; 851 AA.
AC H1YYS2;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=Metlim_2961 {ECO:0000313|EMBL:EHQ36994.1};
OS Methanoplanus limicola DSM 2279.
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanomicrobiales; Methanomicrobiaceae; Methanoplanus.
OX NCBI_TaxID=937775 {ECO:0000313|EMBL:EHQ36994.1, ECO:0000313|Proteomes:UP000005741};
RN [1] {ECO:0000313|EMBL:EHQ36994.1, ECO:0000313|Proteomes:UP000005741}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 2279 {ECO:0000313|EMBL:EHQ36994.1,
RC ECO:0000313|Proteomes:UP000005741};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Peters L., Mikhailova N., Lu M.,
RA Kyrpides N., Mavromatis K., Ivanova N., Markowitz V., Cheng J.-F.,
RA Hugenholtz P., Woyke T., Wu D., Wirth R., Brambilla E.-M., Klenk H.-P.,
RA Eisen J.A.;
RT "The Improved High-Quality Draft genome of Methanoplanus limicola DSM
RT 2279.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CM001436; EHQ36994.1; -; Genomic_DNA.
DR AlphaFoldDB; H1YYS2; -.
DR STRING; 937775.Metlim_2961; -.
DR PATRIC; fig|937775.9.peg.3311; -.
DR HOGENOM; CLU_000445_114_58_2; -.
DR InParanoid; H1YYS2; -.
DR OrthoDB; 3369at2157; -.
DR Proteomes; UP000005741; Chromosome.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00130; PAS; 4.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 4.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR013655; PAS_fold_3.
DR NCBIfam; TIGR00229; sensory_box; 4.
DR PANTHER; PTHR43304:SF1; PAC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43304; PHYTOCHROME-LIKE PROTEIN CPH1; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF13426; PAS_9; 2.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00086; PAC; 3.
DR SMART; SM00091; PAS; 4.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 4.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 3.
DR PROSITE; PS50112; PAS; 4.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:EHQ36994.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000005741};
KW Transferase {ECO:0000313|EMBL:EHQ36994.1}.
FT DOMAIN 173..212
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 216..268
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 269..339
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 393..447
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 463..513
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 514..570
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 587..639
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 650..847
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 851 AA; 94736 MW; 941C3274D6CCF1DF CRC64;
MSDDSNCSIS AGKKCLDKLS ELISLEVSGD EIYGIMAEII SSVFREPENT GAVISVGDEV
WHSSSYDSSK ECPVFLKRNL ELSGISYGYI NVVYYGSSYS GDEYFTDADE LFLDAVSCRI
LIICLKDSSR AELNRCNADA GAYRQILNNS PVIAFLWETG EGWPVRFVSD NVSVLGYSPD
DFYSGKILYA DLIHPDDLKR VEDEISGHLS AGADDYSQEY RVFNRDGELR NIYDRTIVRR
DEEGSPVLFE GIIIDITERV VTEEELKLAN EKYSTVFSLN PDVIILSTLD EGVVLEVNDR
WESFSGIQRD DVIGRKILDL NFYLCHEDRE RYVRELEESG SVLNFELDLN IQDMVRTVFM
SGRIIELEDA KCLITIIHDM TGQKIIEEKL KESEEKFRAV SETATDAICI MDDSGAVVFW
NKAAGEMFGY SSGDVSGRNF VDVFVPEGGN IGAGDGLYPY INKIFESELL TRDSVRVPVE
ISSSVLESGG EKFIVSIIRD ISERKKYEDE LKDAAIKIRT VFDSIGDAMY VIDRDYSIVD
VNKGIYDAFG FKPEDLTGRK CYSVFHGADK PCELCAAGGV FKTGTSGRVE KSVINPDGSV
AYYDTFGSPI TDLSGNVIQA VISARNITDM NNYRSSLEEA NKKLNLLSGI TRHDILNSIT
IATGYLGLMK ENIPAEDRDY ASKLEISIKN IQRQIEFTRD YQDMGVKPPE WQVIEPIILE
CLSEGGGVPS GVHVTLEIKP VVVYADVMLR KAFCNIITNA YKHAFGMKNL SVISGNENGN
LLIRIYDDGS GVPEDKKESI FRPAFGRKHG YGLFLVREIL SITGITIKEM GGEGEGACFE
ITVPSGKWQS V
//
