ID H2CAR2_9LEPT Unreviewed; 692 AA.
AC H2CAR2;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Tetratricopeptide TPR_2 repeat-containing protein {ECO:0000313|EMBL:EHQ08440.1};
GN ORFNames=Lepil_3787 {ECO:0000313|EMBL:EHQ08440.1};
OS Leptonema illini DSM 21528.
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptonema.
OX NCBI_TaxID=929563 {ECO:0000313|EMBL:EHQ08440.1, ECO:0000313|Proteomes:UP000005737};
RN [1] {ECO:0000313|EMBL:EHQ08440.1, ECO:0000313|Proteomes:UP000005737}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21528 {ECO:0000313|EMBL:EHQ08440.1,
RC ECO:0000313|Proteomes:UP000005737};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Peters L., Mikhailova N., Held B.,
RA Kyrpides N., Mavromatis K., Ivanova N., Markowitz V., Cheng J.-F.,
RA Hugenholtz P., Woyke T., Wu D., Gronow S., Wellnitz S., Brambilla E.-M.,
RA Klenk H.-P., Eisen J.A.;
RT "The Improved High-Quality Draft genome of Leptonema illini DSM 21528.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JH597773; EHQ08440.1; -; Genomic_DNA.
DR AlphaFoldDB; H2CAR2; -.
DR STRING; 183.GCA_002009735_02158; -.
DR HOGENOM; CLU_025125_0_0_12; -.
DR Proteomes; UP000005737; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 4.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR013105; TPR_2.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR45586:SF1; SLR0626 PROTEIN; 1.
DR PANTHER; PTHR45586; TPR REPEAT-CONTAINING PROTEIN PA4667; 1.
DR Pfam; PF13432; TPR_16; 4.
DR Pfam; PF14559; TPR_19; 1.
DR Pfam; PF07719; TPR_2; 1.
DR SMART; SM00028; TPR; 13.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS50005; TPR; 9.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005737};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 48..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 168..201
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 236..269
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 273..306
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 307..340
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 341..374
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 375..408
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 412..445
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 525..558
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 640..673
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ SEQUENCE 692 AA; 77820 MW; 0DC2379C9AA60D36 CRC64;
MAKNRLMFEP DGPETIRPAP EKENETIEYG DPVYLDGTAR SVRSFRTLII SGVILILLLV
IGAGAFYLWR SAPEGSPEGR ISLDGARDRY YIPESDLTDA LKKGRQQYLQ LARDDARRTF
QKILDESTSD KERSIAHIFL GVMALEEDRP GQAKHHFLSA LKLDESSVGA LINLAIVERK
LGNREEAQRY AEQAKELAPN DPAVAMILAN LLLESSDPEK AEEIYREGMS RSPDDTIMRY
NLGLALIRQN KLDEAELEFN RLVEMFPSDP LAVRALAYLG QIAFLKNRPE QAVQYYRRAI
GLAPDEARYH YNLGVVLLRM RDNQGALEAF DNALKAGGSD ADVFQNLALA YERLNEPTLA
AKALERALLI NPQSVEGLFQ LGDLYHRQKD LLRAAENYRK IVNITPGDTN TKEALIRLGR
VYREMERYQD SADVLGRAVT LSPNEGQVLY ELGLTYRMGN RFDDAVAVWR KALQNGVKLE
RADERTIRLA LGDSYRAKGA YDLAINEYRQ VEGRNREAPV VEDDAELHLR LGALYRDLKD
AGKASEYYRR VYEGASSSPA QRRDAAKDMA SLYLKDADRA SLDEAGSWAY KAARLDQSDA
ETQLLRAEIL LRNESGVDRE KAIEILMAVA HSRLPSGLEA KTYLLLGDAY YKNGEYRRAV
EALETASEYD PGNSEILKKK RLAVSALRSE GR
//
