ID   H2CDK3_9LEPT            Unreviewed;       128 AA.
AC   H2CDK3;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=HNH endonuclease {ECO:0000313|EMBL:EHQ06536.1};
GN   ORFNames=Lepil_1853 {ECO:0000313|EMBL:EHQ06536.1};
OS   Leptonema illini DSM 21528.
OC   Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC   Leptonema.
OX   NCBI_TaxID=929563 {ECO:0000313|EMBL:EHQ06536.1, ECO:0000313|Proteomes:UP000005737};
RN   [1] {ECO:0000313|EMBL:EHQ06536.1, ECO:0000313|Proteomes:UP000005737}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 21528 {ECO:0000313|EMBL:EHQ06536.1,
RC   ECO:0000313|Proteomes:UP000005737};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Peters L., Mikhailova N., Held B.,
RA   Kyrpides N., Mavromatis K., Ivanova N., Markowitz V., Cheng J.-F.,
RA   Hugenholtz P., Woyke T., Wu D., Gronow S., Wellnitz S., Brambilla E.-M.,
RA   Klenk H.-P., Eisen J.A.;
RT   "The Improved High-Quality Draft genome of Leptonema illini DSM 21528.";
RL   Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; JH597773; EHQ06536.1; -; Genomic_DNA.
DR   AlphaFoldDB; H2CDK3; -.
DR   STRING; 183.GCA_002009735_02830; -.
DR   HOGENOM; CLU_1956879_0_0_12; -.
DR   Proteomes; UP000005737; Unassembled WGS sequence.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   CDD; cd00085; HNHc; 1.
DR   Gene3D; 1.10.30.50; -; 1.
DR   InterPro; IPR029471; HNH_5.
DR   InterPro; IPR003615; HNH_nuc.
DR   PANTHER; PTHR33877; SLL1193 PROTEIN; 1.
DR   PANTHER; PTHR33877:SF1; TYPE IV METHYL-DIRECTED RESTRICTION ENZYME ECOKMCRA; 1.
DR   Pfam; PF14279; HNH_5; 1.
DR   SMART; SM00507; HNHc; 1.
PE   4: Predicted;
KW   Endonuclease {ECO:0000313|EMBL:EHQ06536.1};
KW   Hydrolase {ECO:0000313|EMBL:EHQ06536.1};
KW   Nuclease {ECO:0000313|EMBL:EHQ06536.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005737}.
FT   DOMAIN          32..83
FT                   /note="HNH nuclease"
FT                   /evidence="ECO:0000259|SMART:SM00507"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          102..128
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   128 AA;  14653 MW;  8A7954A73A76CE70 CRC64;
     MNAEPGFDPF FAPDAKHVQR EKEKAKKLRD SGWWNRKRSD GICYYCRRKF KPNELTMDHL
     IPLSRGGSST KENIVPCCKE CNNRKKYLMP AEFADLIAKE RAEREKAQSV NAADDGEGPS
     TRSDGEQK
//